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pro vyhledávání: '"Robert R. Friis"'
Macroautophagy is a process in which cytoplasmic components, including whole organelles, are degraded within lysosomes. Basally, this process is essential for homeostasis and is constitutively functional in most cells, but it can also be implemented
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e67373d742f0072558cf1b3c5415cb
https://eprints.gla.ac.uk/155491/1/155491.pdf
https://eprints.gla.ac.uk/155491/1/155491.pdf
Autor:
Robert R. Friis, Rajagopala Sridaran, Ricky R. Lareu, Markus D. Lacher, Arun Dharmarajan, Cara K. Bradley
Publikováno v:
Biology of Reproduction. 68:2232-2240
We sought to investigate the role inhibitor of apoptosis proteins (IAPs) play in the life cycle of the corpus luteum (CL) of the rat. We isolated two clones with amino acid homology to rat IAP2 (BIRC 3) and three to rat IAP3 (rIAP3; BIRC 4). The expr
Publikováno v:
APOPTOSIS. 8:389-397
Ovulation is a complex, multi-factorial event that involves the degeneration of a specific area of the follicular and ovarian surface via apoptosis. Many apoptosis related genes have been identified in the ovary. Secreted Frizzled Related Protein 4 (
Publikováno v:
Journal of Dairy Research. 68:699-703
Milk ejection and milk removal is considerably influenced by the sympathetic nervous system. Stimulation of α-adrenergic receptors by administration of α-adrenergic agonists inhibits alveolar milk ejection and milk removal in dairy cows due to smoo
Autor:
Anu Srinivasan, Anna Baltzer, Robert R. Friis, Claudio Vallan, Arunasalam Dharmarajan, Andreas Marti, Rolf Jaggi, Philipp M. Ritter
Publikováno v:
Cell Death & Differentiation. 6:1190-1200
Physiological apoptosis in mammals is a type of programmed cell death, an important element in the developmental repertoire ensuring tissue homeostasis and proper disposal of cells that are no longer needed, such as milk-producing epithelial cells in
Autor:
Ke Guo, Susanne Saurer, Zhiwei Feng, Wolfgang Bielke, Vladimir Wolf, Robert R. Friis, Arun Dharmarajan
Publikováno v:
Biology of Reproduction. 58:739-746
The involution of the corpus luteum (CL) at parturition is an example of physiological apoptosis, a complex process involving massive vascular regression while luteal cells undergo apoptosis. In the present study, changes in gene expression associate
Publikováno v:
Cell Death & Differentiation. 4:114-124
Apoptosis plays a striking role in the hormone-dependent involution of the mammary gland, but it has proved difficult to distinguish between the 'cell death' associated genes and the 'tissue remodelling' genes which are expressed concurrently. To ide
Autor:
Robert R. Friis, Hans-Uwe Simon
Publikováno v:
Autophagy
Both apoptotic and autophagic pathways are activated in cells during anticancer treatment using DNA-damaging agents. Thus, the outcome is balanced between apoptotic cell death and enhanced autophagy, with the possibility of prolonged cell survival. I
Autor:
Dipak Maskey, Robert R. Friis, Inès Schmid, Inti Zlobec, Aurel Perren, Hans-Uwe Simon, Shida Yousefi
Publikováno v:
Nature Communications
Maskey, Dipak; Yousefi, Shida; Schmid, Ines; Zlobec, Inti; Perren, Aurel; Friis, Robert; Simon, Hans-Uwe (2013). ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy. Nature communications, 4(1), p. 2130. Nature Publishing Group 10.1038/ncomms3130
Maskey, Dipak; Yousefi, Shida; Schmid, Ines; Zlobec, Inti; Perren, Aurel; Friis, Robert; Simon, Hans-Uwe (2013). ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy. Nature communications, 4(1), p. 2130. Nature Publishing Group 10.1038/ncomms3130
Anticancer drug therapy activates both molecular cell death and autophagy pathways. Here we show that even sublethal concentrations of DNA-damaging drugs, such as etoposide and cisplatin, induce the expression of autophagy-related protein 5 (ATG5), w
Autor:
Kristen Sejrsen, Carlos Wotzkow, Orlando Mani, Meike Körner, Robert R. Friis, Christiane Albrecht, C.E. Ontsouka, Martin Tang Sørensen, Rupert M. Bruckmaier
Publikováno v:
Mani, O, Koerner, M, Sørensen, M T, Sejrsen, K, Wotzkow, C, Ontsouka, E C, Friis, R R, Bruckmaier, R M & Albrecht, C 2010, ' Expression, localization and functional model of cholesterol transporters in lactating and nonlactating mammary tissues of murine, bovine, and human origin ', American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, vol. 299, no. 2, pp. R642-R654 . https://doi.org/10.1152/ajpregu.00723.2009
Members of the ATP-binding cassette (ABC) transporters play a pivotal role in cellular lipid efflux. To identify candidate cholesterol transporters implicated in lipid homeostasis and mammary gland (MG) physiology, we compared expression and localiza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e088f716fe0e948bbdb2e9000d1293
https://pure.au.dk/portal/da/publications/expression-localization-and-functional-model-of-cholesterol-transporters-in-lactating-and-nonlactating-mammary-tissues-of-murine-bovine-and-human-origin(9455a230-7d2b-11df-a7a3-000ea68e967b).html
https://pure.au.dk/portal/da/publications/expression-localization-and-functional-model-of-cholesterol-transporters-in-lactating-and-nonlactating-mammary-tissues-of-murine-bovine-and-human-origin(9455a230-7d2b-11df-a7a3-000ea68e967b).html