Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Robert R. Eady"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Quinol-dependent nitric oxide reductases (qNORs) are considered members of the respiratory heme-copper oxidase superfamily, are unique to bacteria, and are commonly found in pathogenic bacteria where they play a role in combating the host im
Externí odkaz:
https://doaj.org/article/1afe9520cdcc4df4bab359b25a8721a7
Autor:
Daisuke Sasaki, Tatiana F. Watanabe, Robert R. Eady, Richard C. Garratt, Svetlana V. Antonyuk, S. Samar Hasnain
Publikováno v:
IUCrJ, Vol 7, Iss 3, Pp 557-565 (2020)
Copper-containing nitrite reductases (CuNiRs) are found in all three kingdoms of life and play a major role in the denitrification branch of the global nitrogen cycle where nitrate is used in place of dioxygen as an electron acceptor in respiratory e
Externí odkaz:
https://doaj.org/article/b1d7021082c14458bbf1e939a9e3911c
Autor:
Thomas P. Halsted, Keitaro Yamashita, Chai C. Gopalasingam, Rajesh T. Shenoy, Kunio Hirata, Hideo Ago, Go Ueno, Matthew P. Blakeley, Robert R. Eady, Svetlana V. Antonyuk, Masaki Yamamoto, S. Samar Hasnain
Publikováno v:
IUCrJ, Vol 6, Iss 4, Pp 761-772 (2019)
Copper-containing nitrite reductases (CuNiRs) that convert NO2− to NO via a CuCAT–His–Cys–CuET proton-coupled redox system are of central importance in nitrogen-based energy metabolism. These metalloenzymes, like all redox enzymes, are very s
Externí odkaz:
https://doaj.org/article/75b697a700aa49f6a796474d45d8a635
Publikováno v:
IUCrJ, Vol 5, Iss 4, Pp 510-518 (2018)
There are few cases where tyrosine has been shown to be involved in catalysis or the control of catalysis despite its ability to carry out chemistry at much higher potentials (1 V versus NHE). Here, it is shown that a tyrosine that blocks the hydroph
Externí odkaz:
https://doaj.org/article/bfe1f00e94a241d9b3dca6bb287d5b78
Autor:
Sam Horrell, Demet Kekilli, Kakali Sen, Robin L. Owen, Florian S. N. Dworkowski, Svetlana V. Antonyuk, Thomas W. Keal, Chin W. Yong, Robert R. Eady, S. Samar Hasnain, Richard W. Strange, Michael A. Hough
Publikováno v:
IUCrJ, Vol 5, Iss 3, Pp 283-292 (2018)
High-resolution crystal structures of enzymes in relevant redox states have transformed our understanding of enzyme catalysis. Recent developments have demonstrated that X-rays can be used, via the generation of solvated electrons, to drive reactions
Externí odkaz:
https://doaj.org/article/85e6dbab74a14cc1ad0ccf5a3383c86d
Autor:
Thomas P. Halsted, Keitaro Yamashita, Kunio Hirata, Hideo Ago, Go Ueno, Takehiko Tosha, Robert R. Eady, Svetlana V. Antonyuk, Masaki Yamamoto, S. Samar Hasnain
Publikováno v:
IUCrJ, Vol 5, Iss 1, Pp 22-31 (2018)
Synchrotron-based X-ray structural studies of ligand-bound enzymes are powerful tools to further our understanding of reaction mechanisms. For redox enzymes, it is necessary to study both the oxidized and reduced active sites to fully elucidate the r
Externí odkaz:
https://doaj.org/article/87c9109de0cd4a60a6e1fd9c06147529
Autor:
Sam Horrell, Svetlana V. Antonyuk, Robert R. Eady, S. Samar Hasnain, Michael A. Hough, Richard W. Strange
Publikováno v:
IUCrJ, Vol 3, Iss 4, Pp 271-281 (2016)
Relating individual protein crystal structures to an enzyme mechanism remains a major and challenging goal for structural biology. Serial crystallography using multiple crystals has recently been reported in both synchrotron-radiation and X-ray free-
Externí odkaz:
https://doaj.org/article/434ddd5033b24b76b98c35d07d3ccdb2
Publikováno v:
Encyclopedia of Inorganic and Bioinorganic Chemistry. :1-14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c7e33eaed5fb3d3505f34b2c6ef87d
https://doi.org/10.1002/9781119951438.eibc2821
https://doi.org/10.1002/9781119951438.eibc2821
Autor:
Samuel L. Rose, Seiki Baba, Hideo Okumura, Svetlana V. Antonyuk, Daisuke Sasaki, Tobias M. Hedison, Muralidharan Shanmugam, Derren J. Heyes, Nigel S. Scrutton, Takashi Kumasaka, Takehiko Tosha, Robert R. Eady, Masaki Yamamoto, S. Samar Hasnain
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(30)
Many enzymes utilize redox-coupled centers for performing catalysis where these centers are used to control and regulate the transfer of electrons required for catalysis, whose untimely delivery can lead to a state incapable of binding the substrate,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5caf10cd1217cfbe0b0123230e0bec71
https://pubmed.ncbi.nlm.nih.gov/35862453
https://pubmed.ncbi.nlm.nih.gov/35862453
Autor:
Robert R. Eady, S. Samar Hasnain
Publikováno v:
COORDINATION CHEMISTRY REVIEWS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca5b6735d78713491f3a55b015bedf09
