Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Robert R. Becklin"'
Autor:
Linda S Kaltenbach, Eliana Romero, Robert R Becklin, Rakesh Chettier, Russell Bell, Amit Phansalkar, Andrew Strand, Cameron Torcassi, Justin Savage, Anthony Hurlburt, Guang-Ho Cha, Lubna Ukani, Cindy Lou Chepanoske, Yuejun Zhen, Sudhir Sahasrabudhe, James Olson, Cornelia Kurschner, Lisa M Ellerby, John M Peltier, Juan Botas, Robert E Hughes
Publikováno v:
PLoS Genetics, Vol 3, Iss 5, p e82 (2007)
Huntington's disease (HD) is a fatal neurodegenerative condition caused by expansion of the polyglutamine tract in the huntingtin (Htt) protein. Neuronal toxicity in HD is thought to be, at least in part, a consequence of protein interactions involvi
Externí odkaz:
https://doaj.org/article/13bd083a8da44dd192d10530abf31c3c
Autor:
Mike Pyne, Paul B. Robbins, Robert R. Becklin, Kartika Widjaja, Shuping Lai, Sam Thompson, Lawrence Weir, J. Jay Boniface, Yew-Seng J. Ho, John M. Peltier, Moritz von Rechenberg, Cindy Lou Chepanoske, Peter J. Sheffield, Srdjan Askovic, Yuejun Zhen, Justin Savage, Vladimir Kery, Bonnie Richardson, Nafei Xu, Tahmina Mujtaba
Publikováno v:
International Journal of Mass Spectrometry. 238:119-130
Proteomics-based technologies have the potential to accelerate the development of drugs, but such technologies must be well integrated in order to have a positive impact. We describe, herein, a multi-step process for the discovery of protein–protei
Publikováno v:
Biochemistry. 40:10756-10763
The ligand-binding domain (LBD) of the human androgen receptor (hAR LBD), encompassing amino acids (AAs) 647-919, was expressed in Escherichia coli with an N-terminal polyhistidine tag (His(10)-hAR LBD) from a pET-16b vector. The overexpressed protei
Publikováno v:
Biochemical and Biophysical Research Communications. 284:836-844
An N-terminal hexahistidine-tagged full-length human androgen receptor protein (His 6 -hAR) was overexpressed and purified to apparent homogeneity in the presence of dihydrotestosterone (DHT) in our previous studies. In-gel trypsin digestion of the p
Publikováno v:
Analytical Letters. 28:2175-2190
The UV absorption at 200 nm of eleven synthetic peptides, all lacking an aromatic amino acid side chain, was studied. Those peptides were Ala2, Ala3, Ala4, Ala5, Ala6[Hbreve]l. Gly2, Gly3, Gly4, Gly5, SIGSLAK, and PLSRTLSVAAKK. It was determined, usi
Publikováno v:
American Peptide Symposia ISBN: 0792351606
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd39ed968acf2e93b4e25416fa65bfe4
https://doi.org/10.1007/0-306-46862-x_353
https://doi.org/10.1007/0-306-46862-x_353
Autor:
Yuejun Zhen, Kelly Blake, Nafei Xu, John M. Peltier, Robert R. Becklin, Justin Savage, Bonnie Richardson
Publikováno v:
Journal of the American Society for Mass Spectrometry. 15(6)
In this study, a two-dimensional LC-MALDI-TOF/TOF method has been developed for analyzing protein complexes. In our hands, the method has proven to be an excellent strategy for the analysis of protein complexes isolated in pull-down experiments. This
Publikováno v:
Journal of chromatography. B, Biomedical sciences and applications. 695(2)
The mu opioid receptor agonist Tyr- d -Arg-Phe-Lys-Amide ( d - A rg 2 - L ys 4 - D ermorphin 1-4 a mide=DALDA) was infused continuously for 2 h into sheep. The presence of DALDA in ovine plasma was determined by reversed-phase high-performance liquid
Autor:
Jill Soble-Smith, James T. Robertson, Robert R. Becklin, George V. Huffmon, Huey G. Lee, Dominic M. Desiderio, Jih-Lie Tseng
Publikováno v:
Journal of chromatography. B, Biomedical applications. 667(2)
Capillary reversed-phase high-performance liquid chromatography (RP-HPLC) was used to determine acetylmethylprednisolone (A-MP) that had been administered to feline spinal cord tissue. The method used a 300 mm x 0.32 mm I.D. packed capillary octadecy
Autor:
Sudhir Sahasrabudhe, Cornelia Kurschner, Robert E. Hughes, Amit Phansalkar, Linda S. Kaltenbach, Robert R. Becklin, Eliana Romero, Rakesh Chettier, Juan Botas, Lubna Ukani, Russell Bell, Anthony Hurlburt, Cameron Torcassi, Yuejun Zhen, John M. Peltier, James M. Olson, Justin Savage, Cindy Lou Chepanoske, Lisa M. Ellerby, Guang Ho Cha, Andrew D. Strand
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 3, Iss 5, p e82 (2007)
PLoS Genetics, Vol 3, Iss 5, p e82 (2007)
Huntington's disease (HD) is a fatal neurodegenerative condition caused by expansion of the polyglutamine tract in the huntingtin (Htt) protein. Neuronal toxicity in HD is thought to be, at least in part, a consequence of protein interactions involvi