Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Robert R. Annand"'
Autor:
Robert R Annand
Publikováno v:
Methods in Molecular Biology ISBN: 9781071610831
Human-induced pluripotent stem cells (iPSCs) are showing great promise for both disease modeling and regenerative medicine. The choice of reprogramming methods have a significant effect on the outcomes of the experiments. Standard methods, such as Se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54915672041adebd481fa78d12890662
https://doi.org/10.1007/978-1-0716-1084-8_11
https://doi.org/10.1007/978-1-0716-1084-8_11
Autor:
Robert R, Annand
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2239
Human-induced pluripotent stem cells (iPSCs) are showing great promise for both disease modeling and regenerative medicine. The choice of reprogramming methods have a significant effect on the outcomes of the experiments. Standard methods, such as Se
Autor:
David A. Giegel, Cindy A. Sprecher, Walter Kisiel, Robert R. Annand, John A. Mankovich, Jeffrey R. Dahlen, Donald C. Foster, Piet De Dreu, Robert V. Talanian
Publikováno v:
Biochemical Journal. 342:655-665
The regulation of caspases, cysteine proteinases that cleave their substrates after aspartic residues, is poorly understood, even though they are involved in tightly regulated cellular processes. The recently discovered serpin analogue proteinase inh
Publikováno v:
Journal of Molecular Recognition. 10:93-100
Two human and twelve murine monoclonal antibodies directed against the main bee venom allergen phospholipase A2 (PLA) were evaluated for their fine specificity of binding to antigen and their ability to inhibit the enzymatic activity of the antigen.
Publikováno v:
Journal of the American Chemical Society. 115:1088-1094
Nitrogen-15 nuclear magnetic resonance spectroscopy was used to determine the structure of the active-site histidine-70 adduct formed when β-hydroxydecanoyl thiol ester dehydrase from Escherchia coli reacts with the mechanism-based inactivator S-(3-
Publikováno v:
BIOORGANIC & MEDICINAL CHEMISTRY
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
instname
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
instname
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
A QSAR model was developed for predicting intestinal drug permeability, one of the most important parameters when evaluating compounds in drug discovery projects. First, a set of relevant properties for establishing a drug-like chemical space was app
Autor:
Bao Zhu Yu, Farideh Ghomashchi, Ying Lin, Mahendra K. Jain, Michael H. Gelb, Robert R. Annand, Mark S. Hixon
Publikováno v:
Biochemistry. 37(19)
The basis for tight binding of bee venom phospholipase A2 (bvPLA2) to anionic versus zwitterionic phospholipid interfaces is explored by charge reversal mutagenesis of basic residues (lysines/arginines to glutamates) on the putative membrane binding
Autor:
Tariq Ghayur, Molly M. Robertson, Maxine Santoro, Maria Hackett, David A. Giegel, Yun-Wen Peng, Gernot Walter, Matthew J. Brady, Robert R. Annand, Winnie W. Wong, John A. Mankovich
Publikováno v:
The Journal of biological chemistry. 273(21)
Although the available evidence suggests that whereas the caspase family plays a major role in apoptosis, they are not the sole stimulators of death. A random yeast two-hybrid screen of a lymphocyte cDNA library (using caspase-3 as the bait) found an
Autor:
Michael Gmachl, Wei Qiao Chen, Robert R. Annand, Michael H. Gelb, Thomas Dudler, Susheng Wang, Mark Suter, Reto Crameri, Theres Schneider, Robert O. Dempcy
Publikováno v:
Biochimica et biophysica acta. 1165(2)
Bee venom phospholipase A2 (BV-PLA2) is a hydrolytic enzyme that specifically cleaves the sn-2 acyl bond of phospholipids at the lipid/water interface. The same enzyme is also believed to be responsible for some systemic anaphylactic reactions in bee
Publikováno v:
Product R&D. 12:145-149