Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Robert Q. Miao"'
Autor:
Stephanie M. Cossette, Adam J. Gastonguay, Xiaoping Bao, Alexandra Lerch-Gaggl, Ling Zhong, Leanne M. Harmann, Christopher Koceja, Robert Q. Miao, Padmanabhan Vakeel, Changzoon Chun, Keguo Li, Jamie Foeckler, Michelle Bordas, Hartmut Weiler, Jennifer Strande, Sean P. Palecek, Ramani Ramchandran
Publikováno v:
Biology Open, Vol 4, Iss 1, Pp 48-61 (2014)
In this study, we have identified a novel member of the AMPK family, namely Sucrose non-fermenting related kinase (Snrk), that is responsible for maintaining cardiac metabolism in mammals. SNRK is expressed in the heart, and brain, and in cell types
Externí odkaz:
https://doaj.org/article/917d2c284b6c446a82231521f169412d
Autor:
Xiaoyan Bai, Ivan Hernandez-Diaz, Maria Flaquer, Carlo Alberto Ricciardi, Jianting Ke, Fan Fan Hou, Luigi Gnudi, A Hayward, Fulye Argunhan, David A. Long, Jiaqi Pan, Giovanni E. Mann, Robert Q. Miao, Kathryn White, Georgia E Fouli
Publikováno v:
Diabetes. 69(2)
Damage to the vasculature is the primary mechanism driving chronic diabetic microvascular complications such as diabetic nephropathy which manifests as albuminuria. Therefore, treatments that protect the diabetic vasculature have significant therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c00ec56003e019731613cf3dc61758
https://pubmed.ncbi.nlm.nih.gov/31217174
https://pubmed.ncbi.nlm.nih.gov/31217174
Autor:
Wenwen Zhang, Xiaoju Li, Lu-Yuan Li, Wenquan Hu, Miao Yu, Jie Yang, Yan Zhu, Yajun Duan, Chuanrui Ma, Ke Feng, Lipei Liu, Yuanli Chen, Robert Q. Miao, Ying Liu, Jihong Han, Xiaomeng Zhang, Shu Yang, Lei Sun, Xiaoxiao Yang
Publikováno v:
British Journal of Pharmacology. 175:1486-1503
Background and purpose The liver X receptor (LXR) agonist T317 reduces atherosclerosis but induces fatty liver. Metformin activates energy metabolism by activating AMPKα. In this study, we determined if interactions between metformin and T317 could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3ddbe9f8cc6eed77bfac8a04ae893d8
https://doi.org/10.1111/bph.14156
https://doi.org/10.1111/bph.14156
Autor:
Jihong Han, Wenwen Zhang, Rong Xiang, Qixue Wang, Wenquan Hu, Mengyang Liu, Yuanli Chen, Xiaoju Li, Xiaoxiao Yang, Robert Q. Miao, Yajun Duan, David P. Hajjar, Lei Sun, Xingzhe Ma
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35:948-959
Objective— Activation of liver X receptor (LXR) inhibits atherosclerosis but induces hypertriglyceridemia. In vitro, it has been shown that mitogen-activated protein kinase kinase 1/2 (MEK1/2) inhibitor synergizes LXR ligand–induced macrophage AB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fb2512ce8af406ff225d7a7e570b2b4
https://doi.org/10.1161/atvbaha.114.305116
https://doi.org/10.1161/atvbaha.114.305116
Autor:
Baofeng Zhao, Ramani Ramchandran, Paula E. North, George A. Wilkinson, Sreenivasulu Kilari, Nader Rahimi, Indulekha Remadevi, Jing Pan, Robert Q. Miao, Ming You
Publikováno v:
Journal of Biological Chemistry. 288:10265-10274
The endothelial cell-specific chemotaxis receptor (ECSCR) is a cell-surface protein selectively expressed by endothelial cells (ECs), with roles in EC migration, apoptosis and proliferation. Our previous study (Verma, A., Bhattacharya, R., Remadevi,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d89f40884c899701a6b1b1fb7e1335
https://doi.org/10.1074/jbc.m112.413542
https://doi.org/10.1074/jbc.m112.413542
Autor:
Carlos Fernández-Hernando, William C. Sessa, Kenneth D. Harrison, Robert Q. Miao, Yajaira Suárez, Alberto Dávalos
Publikováno v:
Cell Metabolism. 10:208-218
SummaryThe Nogo-B receptor (NgBR) is a recently identified receptor for the N terminus of reticulon 4B/Nogo-B. Other than its role in binding Nogo-B, little is known about the biology of NgBR. To elucidate a basic cellular role for NgBR, we performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aad27cf2cf06fa1b2f93aa0aff60791
https://doi.org/10.1016/j.cmet.2009.07.003
https://doi.org/10.1016/j.cmet.2009.07.003
Autor:
Michelle I. Lin, Robert Q. Miao, Jason Fontana, David Fulton, Kenneth D. Harrison, William C. Sessa
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 28:105-111
Objectives— Heat-shock protein 90 (Hsp90) coordinates the regulation of diverse signaling proteins. We try to develop a new tool to explore the regulatory functions of Hsp90 in endothelial cells (ECs) instead of the existing chemical approaches. Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878275b2ef4fc9a9c106f105fd720d33
https://doi.org/10.1161/atvbaha.107.155499
https://doi.org/10.1161/atvbaha.107.155499
Publikováno v:
American Journal of Physiology-Cell Physiology. 284:C1604-C1613
Kallistatin is a serpin first identified as a specific inhibitor of tissue kallikrein. Our recent studies showed that kallikrein promoted angiogenesis, whereas kallistatin inhibited angiogenesis and tumor growth. This study is aimed to identify the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99dcedbceed68079c15761fe3e20a8a6
https://doi.org/10.1152/ajpcell.00524.2002
https://doi.org/10.1152/ajpcell.00524.2002
Publikováno v:
Blood. 100:3245-3252
Kallistatin is a unique serine proteinase inhibitor (serpin) and a heparin-binding protein. It has been localized in vascular smooth muscle cells and endothelial cells of human blood vessels, suggesting that kallistatin may be involved in the regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaca442022d8a4c958248d30adcb45d6
https://doi.org/10.1182/blood-2002-01-0185
https://doi.org/10.1182/blood-2002-01-0185
Autor:
Indulekha Remadevi, Sreenivas Kilari, George A. Wilkinson, Baofeng Baofeng Zhao, Paula E. North, Ming You, Ramani Ramchandran, Nader Rahimi, Jing Pan, Robert Q. Miao
Publikováno v:
The FASEB Journal. 28
The endothelial cell-specific chemotaxis receptor (ECSCR) is a cell-surface protein selectively expressed by endothelial cells (ECs), with roles in EC migration, apoptosis and proliferation. Our pr...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a853a395158e74d8b7716a5956ee54b
https://doi.org/10.1096/fasebj.28.1_supplement.lb160
https://doi.org/10.1096/fasebj.28.1_supplement.lb160