Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Robert Puskeiler"'
Autor:
Robert Puskeiler, Brian D. Kelley, Annika Kleinjans, Steven J. Meier, Rick St. John, Christian Hakemeyer, Fred Lim, Nathan McKnight, Melody Trexler-Schmidt, Christine Wurth, Frank Zettl
Publikováno v:
Biologicals. 44:306-318
Quality by design (QbD) is a global regulatory initiative with the goal of enhancing pharmaceutical development through the proactive design of pharmaceutical manufacturing process and controls to consistently deliver the intended performance of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84ddf3148a241822ebcccedc5270a2c
https://doi.org/10.1016/j.biologicals.2016.06.004
https://doi.org/10.1016/j.biologicals.2016.06.004
Autor:
Robert Puskeiler, Dirk Weuster-Botz
Publikováno v:
Journal of Biotechnology. 120:430-438
The combined sulfite method is proposed for the measurement of oxygen transfer coefficients, k(L)a, in bio-reactors. The method consists of a steady-state and a dynamic measurement which are carried out under the same experimental conditions and thus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c12f4499d0fec8c877c9ae63a380cd
https://doi.org/10.1016/j.jbiotec.2005.06.016
https://doi.org/10.1016/j.jbiotec.2005.06.016
Autor:
Roger G. Hiller, Julian Catmull, Frank P. Sharples, Robert Puskeiler, David J. Miller, Helen Tweedale
Publikováno v:
Photosynthesis Research. 86:229-240
The coding regions for the N-domain, and full length peridinin-chlorophyll a apoprotein (full length PCP), were expressed in Escherichia coli. The apoproteins formed inclusion bodies from which the peptides could be released by hot buffer. Both the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449fcb879fd095f7f9ed465d17916607
https://doi.org/10.1007/pl00022067
https://doi.org/10.1007/pl00022067
Autor:
Dirk Weuster-Botz, Robert Puskeiler, Klaus Kaufmann, Andreas Kusterer, Gernot T. John, Matthias Arnold
Publikováno v:
Bioprocess and Biosystems Engineering. 28:109-119
Based on electromagnetic simulations as well as on computational fluid dynamics simulations gas-inducing impellers and their magnetic inductive drive were optimized for stirred-tank reactors on a 10 ml-scale arranged in a bioreaction block with 48 bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b2a5667bb5a2dc8babe428aa52ed6b
https://doi.org/10.1007/s00449-005-0011-6
https://doi.org/10.1007/s00449-005-0011-6
Publikováno v:
Biotechnology and Bioengineering. 89:512-523
A novel milliliter-scale bioreactor equipped with a gas-inducing impeller was developed with oxygen transfer coefficients as high as in laboratory and industrial stirred-tank bioreactors. The bioreactor reaches oxygen transfer coefficients of >0.4 s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dbbd9e81cc09f9496471076a59497c3
https://doi.org/10.1002/bit.20352
https://doi.org/10.1002/bit.20352
Autor:
Robert Puskeiler, Dirk Weuster-Botz
Publikováno v:
Chemie Ingenieur Technik. 76:1865-1869
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4de60032e5d74d56b4364384d1fa0fc0
https://doi.org/10.1002/cite.200407026
https://doi.org/10.1002/cite.200407026
Publikováno v:
Cell Engineering ISBN: 9783319103198
Cell culture monitoring is essential for the continuous characterisation of cultivated cells. This helps us to understand each cell line’s growth and metabolism properties and to establish and ensure reproducible cell cultivations. Monitoring not o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::095aba1ded38ddebe163a8c32ce8533c
https://doi.org/10.1007/978-3-319-10320-4_7
https://doi.org/10.1007/978-3-319-10320-4_7
Autor:
Jan Kreuzmann, Heike Schmidt, Stefan Wolf, Christian Hakemeyer, Caroline Schuster, Nicole Bartsch, Robert Puskeiler, Melanie Jacobs, Katharina Didzus
Publikováno v:
BMC Proceedings, Vol 5, Iss Suppl 8, p P12 (2011)
BMC Proceedings
BMC Proceedings
Background The strategy of implementation of the QbD (Quality by design) approach in upstream processing of therapeutic proteins consists of the identification of critical process parameters (CPPs) that have a statistically significant influence on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffbf2cac5ffdfc8b089cf1616db3a901
https://doaj.org/article/d9c74aa7e09b4a20913cd821dd212f58
https://doaj.org/article/d9c74aa7e09b4a20913cd821dd212f58
Publikováno v:
Advances in biochemical engineering/biotechnology. 105
Efficient parallel tools for bioprocess design, consequent application of the concepts for metabolic process analysis as well as innovative downstream processing techniques are enabling technologies for new industrial bioprocesses from an engineering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c408a1c6d0fdad698d73f5a701510629
https://pubmed.ncbi.nlm.nih.gov/17408085
https://pubmed.ncbi.nlm.nih.gov/17408085
Publikováno v:
Advances in Biochemical Engineering/Biotechnology ISBN: 9783540456957
Efficient parallel tools for bioprocess design, consequent application of the concepts for metabolic process analysis as well as innovative downstream processing techniques are enabling technologies for new industrial bioprocesses from an engineering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a10d6e89c040c0fcd8aefb30373829e6
https://doi.org/10.1007/10_2006_034
https://doi.org/10.1007/10_2006_034