Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Robert Porteous"'
Autor:
Jenny Clarkson, Siew Hoong Yip, Robert Porteous, Alexia Kauff, Alison K Heather, Allan E Herbison
Publikováno v:
eLife, Vol 12 (2023)
Evidence suggests that estradiol-sensing preoptic area GABA neurons are involved in the preovulatory surge mechanism necessary for ovulation. In vivo CRISPR-Cas9 editing was used to achieve a 60–70% knockdown in estrogen receptor alpha (ESR1) expre
Externí odkaz:
https://doaj.org/article/fe90a9a69ae24da9aeef3fffb6ac2d50
Autor:
H. James McQuillan, Jenny Clarkson, Alexia Kauff, Su Young Han, Siew Hoong Yip, Isaiah Cheong, Robert Porteous, Alison K. Heather, Allan E. Herbison
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Estrogen secreted by the ovary controls how the brain drives pulsatile reproductive hormone secretion. The authors show that in mice, estrogen receptor alpha within a specific population of hypothalamic kisspeptin neurons is the principal pathway thr
Externí odkaz:
https://doaj.org/article/cf3d7fc05df240f5a328ceea6f85dc31
Autor:
Xinhuai Liu, Shel-Hwa Yeo, H James McQuillan, Michel K Herde, Sabine Hessler, Isaiah Cheong, Robert Porteous, Allan E Herbison
Publikováno v:
eLife, Vol 10 (2021)
The necessity and functional significance of neurotransmitter co-transmission remains unclear. The glutamatergic ‘KNDy’ neurons co-express kisspeptin, neurokinin B (NKB), and dynorphin and exhibit a highly stereotyped synchronized behavior that r
Externí odkaz:
https://doaj.org/article/dd0834127aa343eea0d5fe477907a71f
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
Abstract The roles of kisspeptin signaling outside the hypothalamus in the brain are unknown. We examined here the impact of Kiss1r-deletion on hippocampus-related behaviors of anxiety and spatial learning in adult male mice using two mouse models. I
Externí odkaz:
https://doaj.org/article/78cda37fd14844b8bfc4e7191f312f38
Autor:
David J. Handelsman, Michel K. Herde, David R. Grattan, Eleni C.R. Hackwell, Aaron Singline, Robert Porteous, Allan E. Herbison, Reena Desai, Patricia Haden
Publikováno v:
Endocrinology. 162
The recent use of the tail-tip bleeding approach in mice has enabled researchers to generate detailed pulse and surge profiles of luteinizing hormone (LH) secretion in mice. However, the analysis of pulsatile LH secretion is piecemeal across the fiel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f87ba508b82fc8a0d3b759574182a5c5
https://doi.org/10.1210/endocr/bqab165
https://doi.org/10.1210/endocr/bqab165
Autor:
Gregory T. Bouwer, Greg M. Anderson, Allan E. Herbison, David R. Grattan, Melanie Prescott, Danielle E. Jenkins, Robert Porteous, Karl J. Iremonger, Siew Hoong Yip, Rebecca Campbell, Kelly A. Glendining, Colin H. Brown, Christine L. Jasoni, Zin Khant Aung, Mauro S.B. Silva, Stephen J. Bunn, Betina B. Nair, Rachael A. Augustine
Publikováno v:
Journal of Neuroendocrinology. 33
Chronic stress exerts multiple negative effects on the physiology and health of an individual. In the present study, we examined hypothalamic, pituitary and endocrine responses to 14 days of chronic variable stress (CVS) in male and female C57BL/6J m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595fde4cbe81d6e2038139d3b8a80fd7
https://doi.org/10.1111/jne.12972
https://doi.org/10.1111/jne.12972
Autor:
Siew Hoong Yip, Gregory T. Bouwer, Robert Porteous, David R. Grattan, Zin Khant Aung, Danielle E. Jenkins, Karl J. Iremonger, Kelly A. Glendining, Christine L. Jasoni, Stephen J. Bunn, Colin H. Brown, Melanie Prescott, Greg M. Anderson, Allan E. Herbison, Rachael A. Augustine, Betina B. Nair, Rebecca Campbell, Mauro S.B. Silva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43510017e0d59467e6b61bd2127ee2db
https://doi.org/10.1111/jne.12972/v2/response1
https://doi.org/10.1111/jne.12972/v2/response1
Autor:
Allan E. Herbison, Isaiah Cheong, H. James McQuillan, Sabine Hessler, Robert Porteous, Shel-Hwa Yeo, Michel K. Herde, Xinhuai Liu
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Funder: Health Research Council of New Zealand; FundRef: http://dx.doi.org/10.13039/501100001505
Funder: Wellcome Trust; FundRef: http://dx.doi.org/10.13039/100004440
The necessity and functional significance of neurotransmitter co-transmis
Funder: Wellcome Trust; FundRef: http://dx.doi.org/10.13039/100004440
The necessity and functional significance of neurotransmitter co-transmis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ec10c6d307828b6a77326d55446ad4
Autor:
Xinhuai Liu, Allan E. Herbison, Robert Porteous, Isaiah Cheong, Siew Hoong Yip, Sabine Hessler
Publikováno v:
Endocrinology. 162
Acute stress is a potent suppressor of pulsatile luteinizing hormone (LH) secretion, but the mechanisms through which corticotrophin-releasing hormone (CRH) neurons inhibit gonadotropin-releasing hormone (GnRH) release remain unclear. The activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9714daf35fa0953a3d9210c147acc38a
https://doi.org/10.1210/endocr/bqaa237
https://doi.org/10.1210/endocr/bqaa237