Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Robert Pomponio"'
Autor:
Pierre-Francois Clot, Christine Farenc, Benjamin T. Suratt, Tillmann Krahnke, Agnes Tardat, Peter Florian, Robert Pomponio, Naimish Patel, Maria Wiekowski, Yong Lin, Benjamin Terrier, Heribert Staudinger
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Targeting receptor-interacting serine/threonine protein kinase 1 could mitigate the devastating sequelae of the hyperinflammatory state observed in severe cases of COVID-19. This study explored the immunomodulatory and clinical ef
Externí odkaz:
https://doaj.org/article/4ce4f6b2e2c44d8fa1537ffc9309950d
Autor:
Debbie Robbrecht, Jean‐Jacques Grob, Oliver Bechter, Matteo Simonelli, Bernard Doger, Ivan Borbath, Marcus O. Butler, Tina Cheng, Patricia Martin Romano, Elvire Pons‐Tostivint, Massimo Di Nicola, Giuseppe Curigliano, Min‐Hee Ryu, Alejo Rodriguez‐Vida, Dirk Schadendorf, Elena Garralda, Giovanni Abbadessa, Brigitte Demers, Amele Amrate, Hong Wang, Joon Sang Lee, Robert Pomponio, Rui Wang
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 2, Pp n/a-n/a (2024)
Abstract SAR439459, a ‘second‐generation’ human anti‐transforming growth factor‐beta (TGFβ) monoclonal antibody, inhibits all TGFβ isoforms and improves the antitumor activity of anti‐programmed cell death protein‐1 therapeutics. This
Externí odkaz:
https://doaj.org/article/28412427e6174db093de8737922fa32a
Autor:
Agnes Hincelin‐Mery, Xavier Nicolas, Cathy Cantalloube, Robert Pomponio, Pascale Lewanczyk, Myriam Benamor, Dimitry Ofengeim, Emmanuel Krupka, Jennifer Hsiao‐Nakamoto, Amy Eastenson, Nazem Atassi
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 1, Pp n/a-n/a (2024)
Abstract SAR443820 (DNL788) is a selective, orally bioavailable, brain penetrant inhibitor of receptor‐interacting serine/threonine protein kinase 1 (RIPK1). This phase I first‐in‐human healthy participant study (NCT05795907) was comprised of t
Externí odkaz:
https://doaj.org/article/c0c40af6a8594157bbb4aea061f8bfae
Autor:
Robert Pomponio, Qi Tang, Anthony Mei, Anne Caron, Bema Coulibaly, Joachim Theilhaber, Maximilian Rogers-Grazado, Michele Sanicola-Nadel, Souad Naimi, Reza Olfati-Saber, Cecile Combeau, Jack Pollard, Tun Tun Lin, Rui Wang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 9, Pp 3594-3601 (2022)
Increasing evidence suggests that the presence and spatial localization and distribution pattern of tumor infiltrating lymphocytes (TILs) is associate with response to immunotherapies. Recent studies have identified TGFβ activity and signaling as a
Externí odkaz:
https://doaj.org/article/bde1f3a45ebf44318acb1b184627a242
Autor:
Agnes Hincelin-Mery, Pascale Lewanczyk, Cathy Cantalloube, Xavier Nicolas, Myriam Benamor, Robert Pomponio, Emmanuel Krupka, Dimitry Ofengeim, Amy Eastenson, Li Xiong, Nazem Atassi
Publikováno v:
Thursday, April 27.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2eade97b371f83170a794429ea8a1d0f
https://doi.org/10.1212/wnl.0000000000202201
https://doi.org/10.1212/wnl.0000000000202201
Autor:
Robert, Pomponio, Qi, Tang, Anthony, Mei, Anne, Caron, Bema, Coulibaly, Joachim, Theilhaber, Maximilian, Rogers-Grazado, Michele, Sanicola-Nadel, Souad, Naimi, Reza, Olfati-Saber, Cecile, Combeau, Jack, Pollard, Tun Tun, Lin, Rui, Wang
Publikováno v:
Acta pharmaceutica Sinica. B. 12(9)
Increasing evidence suggests that the presence and spatial localization and distribution pattern of tumor infiltrating lymphocytes (TILs) is associate with response to immunotherapies. Recent studies have identified TGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b4859a952b1d27b52b5d4caa8313940f
https://pubmed.ncbi.nlm.nih.gov/36176910
https://pubmed.ncbi.nlm.nih.gov/36176910
Autor:
Maria Wiekowski, Pierre-Francois Clot, Tillmann Krahnke, Benjamin Terrier, Peter Florian, Agnes Tardat, Benjamin T. Suratt, Yong Lin, Heribert Staudinger, Christine Farenc, Robert Pomponio, Naimish Patel
Publikováno v:
Respiratory infections and bronchiectasis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02cde49a5494e6c8190f1c4347eb1dd9
https://doi.org/10.1183/13993003.congress-2021.pa2363
https://doi.org/10.1183/13993003.congress-2021.pa2363
Autor:
Robert Pomponio, Carrie Hendricks, Sarah Mitchell Bean, Hong Wang, Sergine Brutus, Charles Biddle-Snead, Archit Khosla, Adam Stanford-Moore, Cyrus Hedvat, Qi Tang, Roger Trullo, Brigitte Demers, Rui Wang
Publikováno v:
Cancer Research. 82:5099-5099
Introduction TGFβ is an immunoregulatory cytokine that can function as an oncogenic factor to mediate tumorigenesis, metastasis, and immune escape. Recent studies have shown that TGFβ can drive immune-excluded phenotype in tumor microenvironment (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42b61a34735d4ee18e2d94c2ec8c91cb
https://doi.org/10.1158/1538-7445.am2022-5099
https://doi.org/10.1158/1538-7445.am2022-5099
Publikováno v:
Molecular Genetics and Metabolism. 108:S64
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d1e09a309fe6144e50e914804834be3
https://doi.org/10.1016/j.ymgme.2012.11.164
https://doi.org/10.1016/j.ymgme.2012.11.164