Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Robert Pick"'
Autor:
Louise Madeleine Ince, Coline Barnoud, Lydia Kay Lutes, Robert Pick, Chen Wang, Flore Sinturel, Chien-Sin Chen, Alba de Juan, Jasmin Weber, Stephan J. Holtkamp, Sophia Martina Hergenhan, Jennifer Geddes-McAlister, Stefan Ebner, Paola Fontannaz, Benjamin Meyer, Maria Vono, Stéphane Jemelin, Charna Dibner, Claire-Anne Siegrist, Felix Meissner, Frederik Graw, Christoph Scheiermann
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Circadian rhythms have been shown to influence immune responses, but it is unclear whether this influences responses to vaccines. Here the authors show that dendritic cells migrate in a circadian rhythm meaning that interactions with T cells are alte
Externí odkaz:
https://doaj.org/article/4a62447920cd4f83a5fd19b48d8d06ab
Autor:
Leo Nicolai, Karin Schiefelbein, Silvia Lipsky, Alexander Leunig, Marie Hoffknecht, Kami Pekayvaz, Ben Raude, Charlotte Marx, Andreas Ehrlich, Joachim Pircher, Zhe Zhang, Inas Saleh, Anna-Kristina Marel, Achim Löf, Tobias Petzold, Michael Lorenz, Konstantin Stark, Robert Pick, Gerhild Rosenberger, Ludwig Weckbach, Bernd Uhl, Sheng Xia, Christoph Andreas Reichel, Barbara Walzog, Christian Schulz, Vanessa Zheden, Markus Bender, Rong Li, Steffen Massberg, Florian Gaertner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/ed292487695f4934991736364329901e
Autor:
Leo Nicolai, Karin Schiefelbein, Silvia Lipsky, Alexander Leunig, Marie Hoffknecht, Kami Pekayvaz, Ben Raude, Charlotte Marx, Andreas Ehrlich, Joachim Pircher, Zhe Zhang, Inas Saleh, Anna-Kristina Marel, Achim Löf, Tobias Petzold, Michael Lorenz, Konstantin Stark, Robert Pick, Gerhild Rosenberger, Ludwig Weckbach, Bernd Uhl, Sheng Xia, Christoph Andreas Reichel, Barbara Walzog, Christian Schulz, Vanessa Zheden, Markus Bender, Rong Li, Steffen Massberg, Florian Gaertner
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Breakdown of vascular barriers is a major complication of inflammatory diseases. However, the mechanisms underlying platelet recruitment to inflammatory micro-environments remains unclear. Here, the authors identify haptotaxis as a key effector funct
Externí odkaz:
https://doaj.org/article/4823a6cec2a1460586e33e31ba7a0aef
Autor:
Thomas Bromberger, Sarah Klapproth, Ina Rohwedder, Jasmin Weber, Robert Pick, Laura Mittmann, Soo Jin Min-Weißenhorn, Christoph A. Reichel, Christoph Scheiermann, Markus Sperandio, Markus Moser
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
β2 integrins mediate key processes during leukocyte trafficking. Upon leukocyte activation, the structurally bent β2 integrins change their conformation towards an extended, intermediate and eventually high affinity conformation, which mediate slow
Externí odkaz:
https://doaj.org/article/c3cea8679646465e990db2cdccfaa565
Autor:
Bernd Uhl, Laura AMittmann, Julian Dominik, Roman Hennel, Bojan Smiljanov, Florian Haring, Johanna BSchaubächer, Constanze Braun, Lena Padovan, Robert Pick, Martin Canis, Christian Schulz, Matthias Mack, Ewgenija Gutjahr, Peter Sinn, Jörg Heil, Katja Steiger, Sandip M Kanse, Wilko Weichert, Markus Sperandio, Kirsten Lauber, Fritz Krombach, Christoph A Reichel
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 6, Pp n/a-n/a (2021)
Abstract High intratumoral levels of urokinase‐type plasminogen activator (uPA)‐plasminogen activator inhibitor‐1 (PAI‐1) heteromers predict impaired survival and treatment response in early breast cancer. The pathogenetic role of this protei
Externí odkaz:
https://doaj.org/article/4c70973c2a744ff8b94cdcdb9b282bf8
Autor:
Gabriele Zuchtriegel, Bernd Uhl, Robert Pick, Michaela Ramsauer, Julian Dominik, Laura A. Mittmann, Martin Canis, Sandip Kanse, Markus Sperandio, Fritz Krombach, Christoph A. Reichel
Publikováno v:
Haematologica, Vol 106, Iss 10 (2020)
The recruitment of neutrophils from the microvasculature to the site of injury or infection represents a key event in the inflammatory response. Vitronectin (VN) is a multifunctional macromolecule abundantly present in blood and extracellular matrix.
Externí odkaz:
https://doaj.org/article/8d9ad4479b9e45e684bcfe0a8b6d74ae
Autor:
Ina Rohwedder, Angela R.M. Kurz, Monika Pruenster, Roland Immler, Robert Pick, Tanja Eggersmann, Sarah Klapproth, Jennifer L. Johnson, Sergi Masgrau Alsina, Clifford A. Lowell, Attila Mócsai, Sergio D. Catz, Markus Sperandio
Publikováno v:
Haematologica, Vol 105, Iss 7 (2020)
Leukocyte recruitment into inflamed tissue is highly dependent on the activation and binding of integrins to their respective ligands, followed by the induction of various signaling events within the cell referred to as outside-in signaling. Src fami
Externí odkaz:
https://doaj.org/article/fdb7b307992049d6a38bd8e080a3a16e
Autor:
Federico Andrea Moretti, Sarah Klapproth, Raphael Ruppert, Andreas Margraf, Jasmin Weber, Robert Pick, Christoph Scheiermann, Markus Sperandio, Reinhard Fässler, Markus Moser
Publikováno v:
eLife, Vol 7 (2018)
The role of integrin-mediated adhesion during T cell progenitor homing to and differentiation within the thymus is ill-defined, mainly due to functional overlap. To circumvent compensation, we disrupted the hematopoietic integrin regulator kindlin-3
Externí odkaz:
https://doaj.org/article/f0128f8be844499a97c496d39e30d830
Autor:
Stéphanie Hugues, Melody A. Swartz, Christoph Scheiermann, Robert Pick, Ludovic J. Wrobel, Dale Brighouse, Guillaume Harlé, Julien Angelillo, Juan Dubrot, Laure Garnier, Anastasia O. Gkountidi
Supplementary Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97b74bf408b56577d84cd79640dae10
https://doi.org/10.1158/2326-6066.22543177.v1
https://doi.org/10.1158/2326-6066.22543177.v1
Autor:
Stéphanie Hugues, Melody A. Swartz, Christoph Scheiermann, Robert Pick, Ludovic J. Wrobel, Dale Brighouse, Guillaume Harlé, Julien Angelillo, Juan Dubrot, Laure Garnier, Anastasia O. Gkountidi
Several solid malignancies trigger lymphangiogenesis, facilitating metastasis. Tumor-associated lymphatic vessels significantly contribute to the generation of an immunosuppressive tumor microenvironment (TME). Here, we have investigated the ability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2363ce973488adde34a9b575d30608b9
https://doi.org/10.1158/2326-6066.c.6550168.v1
https://doi.org/10.1158/2326-6066.c.6550168.v1