Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Robert Philibert"'
Autor:
Allan Andersen, Emily Milefchik, Emma Papworth, Brandan Penaluna, Kelsey Dawes, Joanna Moody, Gracie Weeks, Ellyse Froehlich, Kaitlyn deBlois, Jeffrey D Long, Robert Philibert
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
ABSTRACTCurrently, clinicians use their judgement and indices such as the Prediction of Alcohol Withdrawal Syndrome Scale (PAWSS) to determine whether patients are admitted to hospitals for consideration of withdrawal syndrome (AWS). However, only a
Externí odkaz:
https://doaj.org/article/a64aec19b5b6469f9f6cb17181799700
Autor:
Robert Philibert, Timur K. Dogan, Stacey Knight, Ferhaan Ahmad, Stanley Lau, George Miles, Kirk U. Knowlton, Meeshanthini V. Dogan
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 22 (2023)
Background Coronary heart disease (CHD) is the leading cause of death in the world. Unfortunately, many of the key diagnostic tools for CHD are insensitive, invasive, and costly; require significant specialized infrastructure investments; and do not
Externí odkaz:
https://doaj.org/article/bfe7e7f53a5a4220be172f7367450a9f
Autor:
Man-Kit Lei, Frederick X. Gibbons, Meg Gerrard, Steven R.H. Beach, Kelsey Dawes, Robert Philibert
Publikováno v:
Epigenetics, Vol 17, Iss 13, Pp 1991-2005 (2022)
Smoking and Heavy Alcohol Consumption (HAC) are established risk factors for myriad complex disorders of ageing. Yet many prior studies of Epigenetic Ageing (EA) have shown only modest effects of smoking and drinking on accelerated ageing. One potent
Externí odkaz:
https://doaj.org/article/a7a0b4eac8cd4e44b32a60924e727a6f
Publikováno v:
Addiction Neuroscience, Vol 6, Iss , Pp 100079- (2023)
Cigarette smoking has been associated with epigenetic alterations that may be reversible upon cessation. As the most-studied epigenetic modification, DNA methylation is strongly associated with smoking exposure, providing a potential mechanism that l
Externí odkaz:
https://doaj.org/article/5bce0807c75247ef850dcdcbc6064a5b
Autor:
Allan Andersen, Rachel Reimer, Kelsey Dawes, Ashley Becker, Natasha Hutchens, Shelly Miller, Meesha Dogan, Brandon Hundley, James A Mills, Jeffrey D Long, Robert Philibert
Publikováno v:
Epigenetics, Vol 17, Iss 2, Pp 178-190 (2022)
Increasing use of non-combusted forms of nicotine such as e-cigarettes poses important public health questions regarding their specific risks relative to combusted tobacco products such as cigarettes. To fully delineate these risks, improved biomarke
Externí odkaz:
https://doaj.org/article/ea0c7fafefc443139b66c44813b50a2c
Autor:
Kelsey Dawes, Allan Andersen, Rachel Reimer, James A. Mills, Eric Hoffman, Jeffrey D. Long, Shelly Miller, Robert Philibert
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Numerous studies have shown that cg05575921 methylation decreases in response to smoking. However, secondary to methodological issues, the magnitude and dose dependency of that response is as of yet unclear. This lack of certainty is a barri
Externí odkaz:
https://doaj.org/article/f9a2397189974920a5250144371a2f3c
Autor:
Robert Philibert, Jeffrey D. Long, James A. Mills, S. R. H. Beach, Frederick X. Gibbons, Meg Gerrard, Ron Simons, Paulo B. Pinho, Douglas Ingle, Kelsey Dawes, Timur Dogan, Meeshanthini Dogan
Publikováno v:
Epigenetics, Vol 16, Iss 10, Pp 1135-1149 (2021)
Mortality assessments are conducted for both civil and commercial purposes. Recent advances in epigenetics have resulted in DNA methylation tools to assess risk and aid in this task. However, widely available array-based algorithms are not readily tr
Externí odkaz:
https://doaj.org/article/72120a33dd11423ab44ed7d7046c9150
Publikováno v:
Epigenetics, Vol 16, Iss 9, Pp 969-979 (2021)
Currently, the most commonly used biomarker of alcohol consumption patterns is carbohydrate-deficient transferrin (CDT). However, the CDT has limited sensitivity and requires the use of blood. Recently, we have shown that digital DNA methylation tech
Externí odkaz:
https://doaj.org/article/dd07be2bafa84c39a2744a21a1e89e88
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Objective: Evolving patterns of nicotine and cannabis use by adolescents require new tools to understand the changing epidemiology of these substances. Here we describe the use of a novel epigenetic biomarker sensitive to both tobacco and cannabis sm
Externí odkaz:
https://doaj.org/article/a841d931325d4be49f3df6eb9b05999f
Epigenetic Analyses of Alcohol Consumption in Combustible and Non-Combustible Nicotine Product Users
Publikováno v:
Epigenomes, Vol 5, Iss 3, p 18 (2021)
Alcohol and tobacco use are highly comorbid and exacerbate the associated morbidity and mortality of either substance alone. However, the relationship of alcohol consumption to the various forms of nicotine-containing products is not well understood.
Externí odkaz:
https://doaj.org/article/368a1dfd011c4578a921e62e14aa4ea5