Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Robert Parkhill"'
Autor:
Atul Asati, Olga Kachurina, Alex Karol, Vipra Dhir, Michael Nguyen, Robert Parkhill, Diana Kouiavskaia, Konstantin Chumakov, William Warren, Anatoly Kachurin
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0144261 (2016)
Neutralizing antibodies induced by vaccination or natural infection play a critically important role in protection against the viral diseases. In general, neutralization of the viral infection occurs via two major pathways: pre- and post-attachment m
Externí odkaz:
https://doaj.org/article/cceee437d4614e3795699b0b20996615
Autor:
Michael Nguyen, Katherine Fries, Rawia Khoury, Lingyi Zheng, Branda Hu, Stephen W. Hildreth, Robert Parkhill, William Warren
Publikováno v:
SLAS Technology. 21:287-296
The hemagglutination inhibition (HAI) assay quantifies the level of strain-specific influenza virus antibody present in serum and is the standard by which influenza vaccine immunogenicity is measured. The HAI assay endpoint requires real-time monitor
Autor:
Konstantin Chumakov, Atul Asati, Michael Nguyen, Vipra Dhir, Diana Kouiavskaia, Robert Parkhill, William H. Warren, Alex Karol, Anatoly Kachurin, Olga Kachurina
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0144261 (2016)
PLoS ONE
PLoS ONE
Neutralizing antibodies induced by vaccination or natural infection play a critically important role in protection against the viral diseases. In general, neutralization of the viral infection occurs via two major pathways: pre- and post-attachment m
Autor:
Robert Parkhill, Burdin Nicolas, Anthony M. Byers, Olga Kachurina, Charlotte Vernhes, Noëlle Mistretta, Nithya Swaminathan, Tenekua Tapia, William L. Warren, Michael N. Nguyen, Donald Drake, Janice M. Moser, Vaughan Wittman, Tirumalai Kamala, Inderpal Singh, Vipra Dhir, Monique Moreau, Anatoly Kachurin, Jyoti Gangur
Publikováno v:
Disruptive Science and Technology. 1:28-40
Video The development of vaccines and immunotherapeutics is hampered by the lack of appropriate in vitro assays by which to test these compounds against the human immune system. By recognizing the key cellular elements (concentration and types of cel
Autor:
Cecilia O’Brien, Jennifer Brannan, Ana Kuehne, Nicole M. Josleyn, Robert Parkhill, Darin Edwards, John M. Dye
Publikováno v:
The Journal of Immunology. 200:126.32-126.32
Category A agents, such as Ebola virus, pose a great risk to national security because of high rates of transmission and mortality and the gravity of impact to public health. The use of Ebola virus as a bioweapon is a significant concern, and rapid d
Autor:
Nicole M. Josleyn, Ana Kuehne, Cecilia O’Brien, Jennifer Brannan, Darin Edwards, Robert Parkhill, John M. Dye
Publikováno v:
The Journal of Immunology. 200:126.30-126.30
Ebola virus causes a severe and often fatal hemorrhagic fever in people, for which no approved vaccines or therapeutics are available. Disease pathogenesis and countermeasure studies are typically performed using animal models; however, ex vivo model
Autor:
Riyaz Mehta, Guzman Sanchez-Schmitz, Anatoly Kachurin, Louis Poisson, William L. Warren, Heather Fahlenkamp, Eric Mishkin, Tenekua Tapia, Haifeng Song, Vipra Dhir, Del C. Leistritz, Russell Higbee, Anthony M. Byers, Santosh Pawar, Yifan Ma, Inderpal Singh, Luis A. Mosquera, Jyoti Gangur, Mike Nguyen, Olga Kachurina, Janice M. Moser, Vaughan Wittman, Robert Parkhill, Donald Drake, Brian C. Schanen
Publikováno v:
Alternatives to Laboratory Animals. 37:19-27
While the duration and size of human clinical trials may be difficult to reduce, there are several parameters in pre-clinical vaccine development that may be possible to further optimise. By increasing the accuracy of the models used for pre-clinical
Publikováno v:
Advanced Functional Materials. 16:1685-1693
Polymer scaffolds intended to provide a substrate for cell attachment and proliferation benefit if the geometric architecture, mechanical properties, and surface chemistry are controllable within the range applicable for the target tissue. Such scaff
Autor:
Robert Parkhill, Alice L. Stone, Mark W. Simpkins, Cynthia M. Smith, Robert L. Stewart, William L. Warren, Stuart K. Williams, Anatoly Kachurin
Publikováno v:
Tissue Engineering. 10:1566-1576
The primary emphasis of tissue engineering is the design and fabrication of constructs for the replacement of nonfunctional tissue. Because tissue represents a highly organized interplay of cells and extracellular matrix, the fabrication of replaceme
Publikováno v:
Journal of Luminescence. :617-621
Time-resolved measurement of electron temperature was performed through femtosecond studies of highly excited electrons in aluminum alloy, and the process of electron–lattice energy transfer was measured to be 1–3 ps, increasing with the laser fl