Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Robert P. Pierce"'
Autor:
Kathryn A. K. Finton, Peter B. Rupert, Della J. Friend, Ana Dinca, Erica S. Lovelace, Matthew Buerger, Domnita V. Rusnac, Ulysses Foote-McNabb, William Chour, James R. Heath, Jean S. Campbell, Robert H. Pierce, Roland K. Strong
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
MHC class I “single-chain trimer” molecules, coupling MHC heavy chain, β2-microglobulin, and a specific peptide into a single polypeptide chain, are widely used in research. To more fully understand caveats associated with this design that may a
Externí odkaz:
https://doaj.org/article/738bbd7365bf4134a8132bf3cd7b009a
Autor:
Darci Phillips, Magdalena Matusiak, Belén Rivero Gutierrez, Salil S. Bhate, Graham L. Barlow, Sizun Jiang, Janos Demeter, Kimberly S. Smythe, Robert H. Pierce, Steven P. Fling, Nirasha Ramchurren, Martin A. Cheever, Yury Goltsev, Robert B. West, Michael S. Khodadoust, Youn H. Kim, Christian M. Schürch, Garry P. Nolan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
PD-1 blockade is effective for only a subset of patients with cutaneous T cell lymphomas. Here, the authors report a spatial biomarker that uses immune and cancer cell topography to predict response to PD-1 blockade in this disease.
Externí odkaz:
https://doaj.org/article/185b95b3ae0241efb2f75ef0ed8fba8c
Publikováno v:
Antibodies, Vol 12, Iss 3, p 55 (2023)
Immune checkpoints and other immunoregulatory targets can be difficult to precisely target due to expression on non-tumor immune cells critical to maintaining immune homeostasis in healthy tissues. On-target/off-tumor binding of therapeutics results
Externí odkaz:
https://doaj.org/article/0e0955ff91804c98a568f65c79a9c7e1
Autor:
Vladimir Makarov, Paul Nghiem, Jaehyuk Choi, Timothy A Chan, Kimberly S Smythe, Jean S Campbell, Robert H Pierce, Raphael Gottardo, Candice Church, David M Koelle, Thomas Pulliam, Natalie Longino, Song Y Park, Nadeem Riaz, Lichen Jing, Robert Amezquita
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background Merkel cell carcinoma (MCC) often responds to PD-1 pathway blockade, regardless of tumor-viral status (~80% of cases driven by the Merkel cell polyomavirus (MCPyV)). Prior studies have characterized tumor-specific T cell responses to MCPyV
Externí odkaz:
https://doaj.org/article/5ad5aa1d8a2c41f09cc92ec9ecc890fa
Autor:
Seth M Pollack, Robin L Jones, Marissa Vignali, Brett A Schroeder, Shihong Zhang, Jose G Mantilla, Kimberly S Smythe, Jean S Campbell, Robert H Pierce, Lee D Cranmer, Michael J Wagner, Bonnie J LaFleur, Brian C Schulte, Natalie A LaFranzo, Rachel M Gittelman, Kevin C Flanagan, Julie Rytlewski, Laura Riolobos, Teresa S Kim, Eleanor Chen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 8 (2021)
Externí odkaz:
https://doaj.org/article/484b994ebf74450d8db188497c041c18
Autor:
Robin L Jones, Erik A Farrar, Jianhong Cao, Venu G Pillarisetty, Stanley R Riddell, Jean Campbell, Brett A Schroeder, Ralph Graeme Black, Shihong Zhang, Karan Kohli, Robert H Pierce, Lu Yao, Theodore Scott Nowicki, Heather Sloan, Dawn Stief, Lee D Cranmer, Douglas S Hawkins, Edward Y Kim
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Background Synovial sarcoma (SS) and myxoid/round cell liposarcoma (MRCL) are ideal solid tumors for the development of adoptive cellular therapy (ACT) targeting NY-ESO-1, as a high frequency of tumors homogeneously express this cancer-testes antigen
Externí odkaz:
https://doaj.org/article/7b2950dec24549d59f93f70ab1f87df2
Autor:
Michael C Jensen, Venu G Pillarisetty, Katherine J Brempelis, Courtney M Cowan, Shannon A Kreuser, Kevin P Labadie, Brooke M Prieskorn, Nicole A P Lieberman, Chibawanye I Ene, Kara W Moyes, Harrison Chinn, Kole R DeGolier, Lisa R Matsumoto, Sara K Daniel, Jason K Yokoyama, Amira D Davis, Virginia J Hoglund, Kimberly S Smythe, Stephanie D Balcaitis, Richard G Ellenbogen, Jean S Campbell, Robert H Pierce, Eric C Holland, Courtney A Crane
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Though currently approved immunotherapies, including chimeric antigen receptor T cells and checkpoint blockade antibodies, have been successfully used to treat hematological and some solid tumor cancers, many solid tumors remain resistant
Externí odkaz:
https://doaj.org/article/c3322864d2c54a13b3b2a3dea90a8cdb
Autor:
Brett A. Schroeder, Karan Kohli, Ryan B. O’Malley, Theresa S. Kim, Robin L. Jones, Robert H. Pierce, Seth M. Pollack
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Gastrointestinal stromal tumor (GIST) is a devastating disease, especially in the setting of metastasis. The natural progression of GIST has been significantly altered by the development of small molecule tyrosine kinase inhibitors (TKIs), including
Externí odkaz:
https://doaj.org/article/5baee4b461124b9aa4eab407e8e25c19
Autor:
Robert P, Pierce, Bernie R, Eskridge, Brandi, Ross, Margaret A, Day, Brooke, Dean, Jeffery L, Belden
Publikováno v:
Applied Clinical Informatics. 13:1040-1052
Objectives Poor electronic health record (EHR) usability is associated with patient safety concerns, user dissatisfaction, and provider burnout. EHR certification requires vendors to perform user testing. However, there are no such requirements for s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9949ae87376fcbe111529759069906
https://doi.org/10.1055/s-0042-1758222
https://doi.org/10.1055/s-0042-1758222
Autor:
Robert S. Pierce, Brian G. Falzon
Publikováno v:
Engineering, Vol 3, Iss 5, Pp 596-607 (2017)
Increasing demand for weight reduction and greater fuel efficiency continues to spur the use of composite materials in commercial aircraft structures. Subsequently, as composite aerostructures become larger and more complex, traditional autoclave man
Externí odkaz:
https://doaj.org/article/00f1c104be87427aaf619bc2e6186172