Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Robert P. Ostrowski"'
Autor:
Emanuela B. Pucko, Robert P. Ostrowski
Publikováno v:
Acta Poloniae Pharmaceutica, Vol 81, Iss 1, Pp 53-69 (2024)
Protein kinase CK2 has become a target of experimental antiglioma therapies as laboratory data are almost uniformly favorable and the number of synthetized CK2 inhibitors is rapidly growing. The evidence of their use for other brain tumors is on the
Externí odkaz:
https://doaj.org/article/404c1d5c560c48d68d0e9e23132b7d9a
Autor:
Danyang Chen, Jinhua Yang, Robert P. Ostrowski, Yunjie Li, Yuxiong Wang, Zeyu Li, Yong Yang, Shiquan Li, Jieming Li, Simin Li, Yonghui Xiong, Shuisheng Rong, Chao Pan, Zhouping Tang
Publikováno v:
Brain Hemorrhages, Vol 4, Iss 3, Pp 116-121 (2023)
Sixty-three patients admitted to 5 hospitals in 2014–2020 for the treatment of severe hypertensive brainstem hemorrhage by CT-guided and bone marker-oriented transcerebellar aspiration were enrolled in this study. The puncture accuracy, duration of
Externí odkaz:
https://doaj.org/article/2abb2592f8b54054880a08cf2a6b9516
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/26bea8f2863c4a0aa2a1c9a33c098f52
Publikováno v:
Brain Hemorrhages, Vol 3, Iss 2, Pp 98-102 (2022)
Intratumoral hemorrhage (ITH) as a variant of intracranial hemorrhage (ICH) is a known, albeit rare, clinical entity. Hemorrhages within brain neoplasms seem to remain underreported, including angiomatous meningioma and pilocytic astrocytoma as well
Externí odkaz:
https://doaj.org/article/26faca25a6414f4a97590e74377fca7f
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
ObjectivesWe investigated the involvement of the proteasome in the mechanism of preconditioning with hyperbaric oxygen (HBO-PC).MethodsThe experiments were performed on male Wistar rats subjected to a transient global cerebral ischemia of 5 min durat
Externí odkaz:
https://doaj.org/article/3697e14e35fb4661aebf0812d07db726
Autor:
Yuanjun Xin, Jie Chen, Hongxia Zhang, Robert P. Ostrowski, Yidan Liang, Jun Zhao, Xiang Xiang, Fuming Liang, Wenqiao Fu, Hao Huang, Xintong Wu, Jun Su, Jiewen Deng, Zhaohui He
Publikováno v:
Cells, Vol 11, Iss 19, p 2976 (2022)
White matter damage (WMD), one of the research hotspots of subarachnoid hemorrhage (SAH), mainly manifests itself as myelin injury and oligodendrocyte differentiation disorder after SAH, although the specific mechanism remains unclear. Dexamethasone-
Externí odkaz:
https://doaj.org/article/ff88ae0b0007495fb62a442aa9995e4a
Autor:
Emanuela B. Pucko, Robert P. Ostrowski
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 331 (2022)
In gliomas, casein kinase 2 (CK2) plays a dominant role in cell survival and tumour invasiveness and is upregulated in many brain tumours. Among CK2 inhibitors, benzimidazole and isothiourea derivatives hold a dominant position. While targeting gliom
Externí odkaz:
https://doaj.org/article/8c5643cba1204b40a18b563c09ccb135
Publikováno v:
Archives of Medical Science, Vol 13, Iss 5, Pp 1217-1223 (2017)
Hemorrhagic stroke, accounting for 10–30% of stroke cases, carries high rates of morbidity and mortality. This review presents the current knowledge on the efficacy of hyperbaric oxygen (HBO)-based modalities in the preclinical research on hemorrha
Externí odkaz:
https://doaj.org/article/c7434216b27445a08f61d133ca00a33d
Publikováno v:
Neurobiology of Disease, Vol 62, Iss , Pp 365-371 (2014)
Brain inflammation may play an important role in the pathophysiology of early brain injury after subarachnoid hemorrhage (SAH). Our aim was to demonstrate brain inflammation development and to determine whether isoflurane, a clinically available vola
Externí odkaz:
https://doaj.org/article/f1c920e4371f4e21864096a17693f695
Autor:
Jun Mu, Robert P. Ostrowski, Yoshiteru Soejima, William B. Rolland, Paul R. Krafft, Jiping Tang, John H. Zhang
Publikováno v:
Neurobiology of Disease, Vol 51, Iss , Pp 133-143 (2013)
Treatments that could extend the therapeutic window of opportunity for stroke patients are urgently needed. Early administration of hyperbaric oxygen therapy (HBOT) has been proven neuroprotective in the middle cerebral artery occlusion (MCAo) in rod
Externí odkaz:
https://doaj.org/article/d68810bec908495799c810d2b893c921