Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Robert P. Hof"'
Publikováno v:
Transplantation. 78:345-351
Background We recently demonstrated that donor medial cells are replaced by smooth muscle alpha-actin (SMA)-expressing host cells in murine carotid allografts. In this study, we investigated neointimal cell dynamics including effects of cyclosporine
Publikováno v:
Transplantation. 76:1166-1170
Background Apolipoprotein E-deficient (apoE-/-) mice spontaneously develop hypercholesterolemia and atherosclerotic lesions. This may be an appropriate background for the development of graft vessel disease. The authors therefore investigated the eff
Publikováno v:
Transplant Immunology. 9:43-49
Objective: The macrolide immunosuppressant RAD and the immunomodulator FTY720 have distinct mechanisms of action. We investigated the efficacy of RAD (everolimus, certican®) alone or in combination with FTY720 on graft survival (GS) and histology in
Publikováno v:
Transplant Immunology. 8:115-124
Objective: The new immunomodulator 2-amino-2-(2-{4-octylphenyl}ethyl)-1,3-propanediol hydrochloride (FTY720) lowers the peripheral lymphocyte count (PLC) by inducing migration of circulating lymphocytes to secondary lymphoid organs. This effect is do
Publikováno v:
Transplantation. 64:20-27
BACKGROUND: Graft vessel disease is a special form of accelerated arteriosclerosis. Because immunological and nonimmunological factors can contribute to graft vessel disease, we developed a model that enables the study of both factors simultaneously.
Autor:
Richard M. Kellogg, Robert P. Hof
Publikováno v:
Tetrahedron: Asymmetry. 5:565-568
Several racemic 1,2-diols bearing a tertiary benzylic alcohol stereogenic center can be esterified regioselectively by vinyl acetate using lipases and esterases in organic media. With the correct choice of enzyme and if the non-phenyl substituent at
Publikováno v:
Cardiovascular Drugs and Therapy. 8:235-244
The effects of the new inotropic agent, SDZ 218-135 [(+)-(S)-4-[3-(4-diphenyl-methyl-1-piperazinyl)-2-hydroxy-propyl]- 6-(2-hydroxyethyl)-5-methyl-1,2,4-triazolo-[1,5-a]pyrimidin-7(4H)-one], were investigated using in vitro and in vivo techniques. In
Publikováno v:
Cardiovascular Research. 28:215-220
Objective: Both calcium antagonists and angiotensin converting enzyme (ACE) inhibitors are known to diminish the development of intimal thickening after a balloon catheter lesion. It was previously shown that narrowing of carotid artery lumen induced
Publikováno v:
Journal of Cardiovascular Pharmacology. 22:499-505
Tropisetron (ICS 205-930) is a novel drug that blocks serotonin (5-HT3) receptors and, at higher concentrations, potassium channels. Programmed electrical stimulation (PES) and tracer microspheres were used to investigate antiarrhythmic, systemic, an
Autor:
E Robertson, Evenou Jp, Markus Rudin, Stirnimann R, Robert P. Hof, Zierhut W, Zerwes Hg, Novosel D
Publikováno v:
Journal of Cardiovascular Pharmacology. 21:937-946
Structural alterations after myocardial infarction (MI) in rats are usually examined only after death of the experimental animal. Magnetic resonance imaging (MRI) allows repeated and noninvasive measurements of important structural [left ventricular