Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Robert P. Hartshorne"'
Autor:
Robert P. Hartshorne, Dirk J. Snyders, Karen M. Knoth, Steven L. Roberds, Michael M. Tamkun, T. Blair, Paul B. Bennett, Sunny Po
Publikováno v:
Journal of cardiovascular electrophysiology
Cardiovascular K+ Channel Molecular Biology. K+ channels represent the most diverse class of voltage-gated ion channels in terms of function and structure. Voltage-gated K+ channels in the heart establish the resting membrane K permeability, modulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e966b01bc44fbc7d676084baf566b57
https://doi.org/10.1111/j.1540-8167.1993.tb01214.x
https://doi.org/10.1111/j.1540-8167.1993.tb01214.x
Publikováno v:
Archives of Biochemistry and Biophysics. 276:47-54
Two-dimensional probability density analysis of single channel current recordings was applied to two purified channel proteins reconstituted in planar lipid bilayers: Torpedo acetylcholine receptors and voltage-sensitive sodium channels from rat brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd787e5abd8931588fcfdb9d4447c802
https://doi.org/10.1016/0003-9861(90)90008-m
https://doi.org/10.1016/0003-9861(90)90008-m
Publikováno v:
FEBS letters. 295(1-3)
A voltage-sensitive K+ channel previously cloned from rat heart designated RK5 (rat Kv4.2) (Roberds and Tamkun, 1991, Proc. Natl. Acad. Sci. USA 88, 1798–1802) was functionally characterized in the Xenopus oocyte expression system. RK5 is a homolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cdfcc63466b7655982c62b2dc877a13
https://pubmed.ncbi.nlm.nih.gov/1722463
https://pubmed.ncbi.nlm.nih.gov/1722463
Publikováno v:
Toxicon. 20:27-40
Neurotoxins that act at specific receptor sites on voltage-sensitive sodium channels have been used as molecular probes to identify and purify protein components of sodium channels from mammalian brain. Photoreactive derivatives of scorpion toxin hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7247074b9d5e61627c0f39378308df
https://doi.org/10.1016/0041-0101(82)90140-4
https://doi.org/10.1016/0041-0101(82)90140-4
Autor:
Robert P. Hartshorne, William A. Catterall, Bernard U. Keller, J A Talvenheimo, Mauricio Montal
Publikováno v:
Annals of the New York Academy of Sciences. 479:293-305
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d87423aa3e4e7c6da1c112c3e1953568
https://doi.org/10.1111/j.1749-6632.1986.tb15576.x
https://doi.org/10.1111/j.1749-6632.1986.tb15576.x
Publikováno v:
Proceedings of the National Academy of Sciences. 78:4620-4624
The saxitoxin (STX) receptor has been purified 740-fold from rat brain by a combination of ion exchange chromatography, wheat germ agglutinin chromatography, and sedimentation on sucrose gradients to a specific activity of 1488 pmol/mg of protein. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::710d8a1b7803a98d2e51e75e1e6d6cd1
https://doi.org/10.1073/pnas.78.7.4620
https://doi.org/10.1073/pnas.78.7.4620
Autor:
Myrta S. Montal, William A. Catterall, J A Talvenheimo, B U Keller, D. J. Feller, Robert P. Hartshorne, D J Messner
Publikováno v:
IUPHAR 9th International Congress of Pharmacology London 1984 ISBN: 9780333371343
The ionic mechanisms underlying electrical excitability in nerve and other excitable tissues have been defined by use of the voltage clamp method (Hodgkin & Huxley, 1952). In this approach the voltage across the excitable membrane is controlled with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caf7db4c48d222c215c6456130793307
https://doi.org/10.1007/978-1-349-17613-7_26
https://doi.org/10.1007/978-1-349-17613-7_26
Publikováno v:
Ion Channel Reconstitution ISBN: 9781475713633
The voltage-sensitive sodium channel mediates the inward sodium current during the depolarizing phase of an action potential. Because of its central role in impulse conduction, it has been the subject of extensive investigations by electrophysiologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de6c153a1cdaa0fbcda79b78c4a25a76
https://doi.org/10.1007/978-1-4757-1361-9_13
https://doi.org/10.1007/978-1-4757-1361-9_13
The ion conduction and voltage dependence of sodium channels purified from rat brain were investigated in planar lipid bilayers in the presence of batrachotoxin. Single channel currents are clearly resolved. Channel opening is voltage dependent and f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc05e36ab3c9359d3fd5ca1ebbf6953
https://europepmc.org/articles/PMC397008/
https://europepmc.org/articles/PMC397008/