Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Robert P. Dickson"'
Autor:
Christopher W. Seymour, MD, MSc, Kelly Lynn Urbanek, MS, Anna Nakayama, Jason N. Kennedy, MS, Rachel Powell, MD, Renã A.S. Robinson, PhD, Kathryn L. Kapp, BS, Timothy R. Billiar, MD, Yoram Vodovotz, PhD, Stacy L. Gelhaus, PhD, Vaughn S. Cooper, PhD, Lu Tang, PhD, Flo Mayr, MD, Katherine M. Reitz, MD, MSc, Christopher Horvat, MD, Nuala J. Meyer, MD, MS, Robert P. Dickson, Derek Angus, MD, Octavia Peck Palmer, PhD
Publikováno v:
Critical Care Explorations, Vol 5, Iss 11, p e0974 (2023)
BACKGROUND:. Sepsis is a common and deadly syndrome, accounting for more than 11 million deaths annually. To mature a deeper understanding of the host and pathogen mechanisms contributing to poor outcomes in sepsis, and thereby possibly inform new th
Externí odkaz:
https://doaj.org/article/7ed111b6ecb34b9ea933120437ef9700
Autor:
Jack Wadden, Brandon S. Newell, Joshua Bugbee, Vishal John, Amy K. Bruzek, Robert P. Dickson, Carl Koschmann, David Blaauw, Satish Narayanasamy, Reetuparna Das
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
A method for detection of somatic variants is presented for the intraoperative evaluation of tumor mutations in less than 30 min, using rapid DNA extraction, in silico optimized LAMP amplification, and a LAMP product analysis tool: LAMPrey.
Externí odkaz:
https://doaj.org/article/4346e61ed01245dda35275953e143eb0
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
A machine learning-based tool, AMAISE, separates microbial and host sequences in metagenomics data without relying on reference genomes to remove host sequences.
Externí odkaz:
https://doaj.org/article/b6cd4a5150814b0bb86f62d0becb24ed
Autor:
Rishi Chanderraj, Christopher A. Brown, Kevin Hinkle, Nicole Falkowski, Robert J. Woods, Robert P. Dickson
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract Background In ecology, population density is a key feature of community analysis. Yet in studies of the gut microbiome, bacterial density is rarely reported. Studies of hospitalized patients commonly use rectal swabs for microbiome analysis,
Externí odkaz:
https://doaj.org/article/dc3e45a047504c1590f252b6cbfe8876
Autor:
Nan Wu, Piyush Ranjan, Changyu Tao, Chao Liu, Ence Yang, Bei He, John R. Erb-Downward, Shining Bo, Jiajia Zheng, Chenxia Guo, Beibei Liu, Lina Sun, Wei Yan, Meng Wang, Wenting Wang, Jianing Wen, Ping Yang, Lin Yang, Qiaoshan Tian, Robert P. Dickson, Ning Shen
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-14 (2021)
Abstract Background Aetiology detection is crucial in the diagnosis and treatment of ventilator-associated pneumonia (VAP). However, the detection method needs improvement. In this study, we used Nanopore sequencing to build a quick detection protoco
Externí odkaz:
https://doaj.org/article/b472120c8d6343a5846ffcdab381dbcb
Autor:
Yuwei Bao, Jack Wadden, John R. Erb-Downward, Piyush Ranjan, Weichen Zhou, Torrin L. McDonald, Ryan E. Mills, Alan P. Boyle, Robert P. Dickson, David Blaauw, Joshua D. Welch
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-16 (2021)
Abstract We present SquiggleNet, the first deep-learning model that can classify nanopore reads directly from their electrical signals. SquiggleNet operates faster than DNA passes through the pore, allowing real-time classification and read ejection.
Externí odkaz:
https://doaj.org/article/400a7cdd3e9a4dc1a17cb22271f19b24
Autor:
Jennifer M. Baker, Kevin J. Hinkle, Roderick A. McDonald, Christopher A. Brown, Nicole R. Falkowski, Gary B. Huffnagle, Robert P. Dickson
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-14 (2021)
Abstract Background Low-biomass microbiome studies (such as those of the lungs, placenta, and skin) are vulnerable to contamination and sequencing stochasticity, which obscure legitimate microbial signal. While human lung microbiome studies have rigo
Externí odkaz:
https://doaj.org/article/fa66e20a7c3643bea5694f1810dcf9c5
Autor:
Ruchi Sharma, Menglian Zhou, Mohamad Hakam Tiba, Brendan M. McCracken, Robert P. Dickson, Christopher E. Gillies, Michael W. Sjoding, Jean A. Nemzek, Kevin R. Ward, Kathleen A. Stringer, Xudong Fan
Publikováno v:
ERJ Open Research, Vol 8, Iss 1 (2022)
Despite the enormous impact on human health, acute respiratory distress syndrome (ARDS) is poorly defined, and its timely diagnosis is difficult, as is tracking the course of the syndrome. The objective of this pilot study was to explore the utility
Externí odkaz:
https://doaj.org/article/24d4f97b95a0456faa77f4d986eaed62
Autor:
Kale S. Bongers, Roderick A. McDonald, Katherine M. Winner, Nicole R. Falkowski, Christopher A. Brown, Jennifer M. Baker, Kevin J. Hinkle, Daniel J. Fergle, Robert P. Dickson
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
Background The microbiome is an important and increasingly-studied mediator of organismal metabolism, although how the microbiome affects metabolism remains incompletely understood. Many investigators use antibiotics to experimentally perturb the mic
Externí odkaz:
https://doaj.org/article/83d6def757b4418a9c582f63700afd31
Autor:
Marel C. E. van Ruissen, Lieuwe D. Bos, Robert P. Dickson, Arjen M. Dondorp, Constance Schultsz, Marcus J. Schultz
Publikováno v:
Intensive Care Medicine Experimental, Vol 7, Iss S1, Pp 1-12 (2019)
Abstract Objective To describe the possible modes of action of probiotics and provide a systematic review of the current evidence on the efficacy of probiotics to prevent ventilator-associated pneumonia (VAP) in critically ill patients. Methods We co
Externí odkaz:
https://doaj.org/article/24563277ca2a47ab9e5a4bf34d23c8e6