Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Robert P. Delong"'
Publikováno v:
Bioengineering, Vol 10, Iss 5, p 512 (2023)
Conserved omicron RNA (COR) is a 40 base long 99.9% conserved sequence in SARS-CoV-2 Omicron variant, predicted to form a stable stem loop, the targeted cleavage of which can be an ideal next step in controlling the spread of variants. The Cas9 enzym
Externí odkaz:
https://doaj.org/article/1e232f8390ee4fa08c4e11dc0aede5d9
Autor:
Elza Neelima Mathew, Miranda N Hurst, Baolin Wang, Vaibhav Murthy, Yuntao Zhang, Robert K DeLong
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243802 (2020)
Zinc oxide (ZnO) NP is considered as a nanoscale chemotherapeutic. Thus, the drug delivery of this inorganic NP is of considerable importance. Ras mutations are common in cancer and the activation of this signaling pathway is a hallmark in carcinoma,
Externí odkaz:
https://doaj.org/article/23f1b79ca75846a6b66de4cb52395977
Autor:
Hanah F. Huber, Majid Jaberi-Douraki, Sarah DeVader, Cesar Aparicio-Lopez, Juliet Nava-Chavez, Xuan Xu, Nuwan Indika Millagaha Gedara, Natasha N. Gaudreault, Robert K. Delong
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 1012 (2021)
The emergence of SARS-CoV-2 variants is cause for concern, because these may become resistant to current vaccines and antiviral drugs in development. Current drugs target viral proteins, resulting in a critical need for RNA-targeted nanomedicines. To
Externí odkaz:
https://doaj.org/article/83313e956ff0473c9b069ebae336eb1e
Publikováno v:
Nanotechnology, Science and Applications, Vol 2010, Iss default, Pp 53-63 (2010)
Robert K DeLong1, Christopher M Reynolds1, Yaneika Malcolm1, Ashley Schaeffer1, Tiffany Severs2, Adam Wanekaya21Department of Biomedical Science (Cell and Molecular Biology Program), 2Department of Chemistry, Missouri State University, Springfield, M
Externí odkaz:
https://doaj.org/article/3b0bcf9de0ff4e4e8350c35b7b12e9a5
Autor:
Jayden McCall, Joshua J. Smith, Kelsey N. Marquardt, Katelin R. Knight, Hunter Bane, Alice Barber, Robert K. DeLong
Publikováno v:
Nanomaterials, Vol 7, Iss 11, p 378 (2017)
Gene therapy and RNA delivery require a nanoparticle (NP) to stabilize these nucleic acids when administered in vivo. The presence of degradative hydrolytic enzymes within these environments limits the nucleic acids’ pharmacologic activity. This st
Externí odkaz:
https://doaj.org/article/0f8e41d4e8c6400a9703214ba108cb4f
Autor:
Vaibhav Murthy, Robert K. Delong
Publikováno v:
Bioengineering, Vol 4, Iss 1, p 13 (2017)
RNA nanotechnology is attracting a great deal of attention recently. As the multiple roles that RNA plays in molecular biology and physiological regulation become clearer, there are many opportunities for engineering RNA-Nanoparticle Complexes (RNA-N
Externí odkaz:
https://doaj.org/article/ddc22a54aa604f25931ddf88365776c4
Autor:
Robert K. DeLong, Lisa Cillessen, Chris Reynolds, Adam Wanekaya, Tiffany Severs, Kartik Ghosh, Michael Fisher, Stephanie Barber, John Black, Ashley Schaeffer, Kristin J. Flores
Publikováno v:
Journal of Nanotechnology, Vol 2012 (2012)
DNA and RNA micro- and nanoparticles are increasingly being used for gene and siRNA drug delivery and a variety of other applications in bionanotechnology. On the nanoscale, these entities represent unique challenges from a physicochemical characteri
Externí odkaz:
https://doaj.org/article/e26172e1c91543b0946d71b1726179ef
Autor:
Kristin J. Flores, Michael Craig, Adam Wanekaya, Lifeng Dong, Kartik Ghosh, Joshua J. Smith, Robert K. DeLong
Publikováno v:
Journal of Nanotechnology, Vol 2012 (2012)
Since the first generation of DNA vaccines was introduced in 1988, remarkable improvements have been made to improve their efficacy and immunogenicity. Although human clinical trials have shown that delivery of DNA vaccines is well tolerated and safe
Externí odkaz:
https://doaj.org/article/e11876f6c7c7489f90f686c701c78003
Autor:
Dale Rex Coman, Robert P. Delong
Publikováno v:
Cancer. 4:610-618
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a79bc4ca3ea9ba36a6b87cb72d825922
https://doi.org/10.1002/1097-0142(195105)4:3<610::aid-cncr2820040312>3.0.co
https://doi.org/10.1002/1097-0142(195105)4:3<610::aid-cncr2820040312>3.0.co
Publikováno v:
Cancer. 3:718-721
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::979ab9475c5a5b4a88dfac4ef48c1942
https://doi.org/10.1002/1097-0142(1950)3:4<718::aid-cncr2820030416>3.0.co
https://doi.org/10.1002/1097-0142(1950)3:4<718::aid-cncr2820030416>3.0.co