Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Robert P. C. Shiu"'
Publikováno v:
Open Journal of Immunology. :210-217
The Prolactin-inducible-protein (PIP)/Gross Cystic Disease Fluid Protein-15 (GCDFP-15) gene is highly expressed in salivary, lacrimal and sweat glands and the protein abundantly found in the secretions that originate from these glands; saliva, tears
Publikováno v:
DNA and cell biology. 35(10)
The propensity for breast cancers to elicit immune responses in patients is well established. The accumulation of tumor infiltrating lymphocytes within the primary breast tumor has been linked to better prognosis and better response to therapy. The p
Autor:
Anne Blanchard, F. Amara, Yvonne Myal, G.G. Hicks, D. Martin, F.E. Castaneda, Robert P. C. Shiu, Andreea Nistor
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 87:859-872
The human prolactin-inducible protein / gross cystic disease fluid protein-15 (hPIP/GCDFP-15) is a secretory glycoprotein found primarily in apocrine tissues including the breast and salivary glands. With largely unknown functions, PIP has been impli
Autor:
Leigh C. Murphy, Anne BlanchardA. Blanchard, Yvonne Myal, Robert P. C. Shiu, A. Yarmill, Michel ChrétienM. Chrétien, Barbara IwasiowB. Iwasiow, Nabil SeidahN. Seidah, Josef V. SilhaJ.V. Silha, Agnes FresnosaA. Fresnosa
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 87:831-838
Elevated production of proprotein convertases (PCs), proteolytic enzymes that posttranslationally modify the biological activities of diverse groups of cellular proteins, is a common occurrence in human breast carcinomas. A transgenic mouse model was
Publikováno v:
Biochemical Pharmacology. 77:1139-1150
Although the primary response to Adriamycin (doxorubicin) in p53 mutant MDA-MB231 and p53 null MCF-7/E6 breast tumor cells is apoptotic cell death, the residual surviving population appears to be in a state of senescence, based on cell morphology, be
Publikováno v:
Archives of Environmental Contamination and Toxicology. 54:84-91
Metallothioneins (MTs) are low-molecular-weight proteins whose physiologic roles are the regulation of essential metals Cu and Zn, sequestration of heavy metals, and free radical scavenging. Induced production of MTs in a wide variety of organisms ex
Autor:
Santanu Deb, Geula Gibori, G. Gibori, Susan Ferguson-Gottschall, Christian Tessier, Robert P. C. Shiu, Anne Prigent-Tessier
Publikováno v:
Endocrinology. 141:3842-3851
Estradiol is known to play an important role in the growth and differentiation of rat uterine stromal cells into decidual cells. In particular, this hormone with progesterone is necessary for blastocyst implantation and subsequent decidualization in
Autor:
Robert P. C. Shiu, Richard E. Cutler, Phillip A. Fields, Mary Hunzicker-Dunn, May C. Robertson, Evelyn T. Maizels, Carl A. Peters
Publikováno v:
Molecular and Cellular Endocrinology. 162:181-191
Protein kinase C (PKC) delta is dramatically upregulated in the corpus luteum in the second half of pregnancy in the rat. To gain insight into the hormonal regulation of PKC delta expression, studies were undertaken to analyze the regulation of PKC d
Autor:
Evelyn T. Maizels, Melvin S. Soloff, Mary Hunzicker-Dunn, May C. Robertson, Robert P. C. Shiu, Carl A. Peters
Publikováno v:
Molecular Endocrinology. 14:576-590
The ability of PRL or rat placental lactogen (rPL)-1 to induce relaxin mRNA expression was analyzed in a luteinized rat granulosa cell culture model. PRL receptor activation induced relaxin mRNA expression in a concentration- and time-dependent manne
Autor:
J W Clark, Robert P. C. Shiu, Nathalie L. Maitre, Calvin P.H. Vary, F. W. Orr, David J. Cole, L Snell, Peter H. Watson
Publikováno v:
British Journal of Cancer
The prolactin-inducible protein (PIP/GCPD15) is believed to originate from a limited set of tissues, including breast and salivary glands, and has been applied as a clinical marker for the diagnosis of metastatic tumours of unknown origin. We have in