Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Robert P Zinzen"'
Autor:
Juan Manuel Gomez, Hendrik Nolte, Elisabeth Vogelsang, Bipasha Dey, Michiko Takeda, Girolamo Giudice, Miriam Faxel, Theresa Haunold, Alina Cepraga, Robert P Zinzen, Marcus Krüger, Evangelia Petsalaki, Yu-Chiun Wang, Maria Leptin
Publikováno v:
eLife, Vol 13 (2024)
The initially homogeneous epithelium of the early Drosophila embryo differentiates into regional subpopulations with different behaviours and physical properties that are needed for morphogenesis. The factors at top of the genetic hierarchy that cont
Externí odkaz:
https://doaj.org/article/b0c680df25ca4144b7b8c28327ad121a
Autor:
Robert P Zinzen, Dmitri Papatsenko
Publikováno v:
PLoS Computational Biology, Vol 3, Iss 5, p e84 (2007)
Formation of spatial gene expression patterns in development depends on transcriptional responses mediated by gene control regions, enhancers. Here, we explore possible responses of enhancers to overlapping gradients of antagonistic transcriptional r
Externí odkaz:
https://doaj.org/article/67343ee894754980a853617a97aa8937
Autor:
Mahmoud M. Ibrahim, Aslihan Karabacak, Alexander Glahs, Ena Kolundzic, Antje Hirsekorn, Alexa Carda, Baris Tursun, Robert P. Zinzen, Scott A. Lacadie, Uwe Ohler
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Divergent transcription from promoters and enhancers occurs in many species, but it is unclear if it is a general feature of all eukaryotic cis regulatory elements. Here the authors define cis regulatory elements in worms, flies, and human; and ident
Externí odkaz:
https://doaj.org/article/ba6afea8491d4c6b9ffb77e4b92a8370
Autor:
Anna Oliveras Martinez, Cledi Alicia Cerda Jara, Guido Mastrobuoni, Andrew Woehler, Stefan Kempa, Anastasiya Boltengagen, Tale Hessler, Ricardo Wurmus, Alessandra Zappulo, Agnieszka Rybak-Wolf, Lisa Emmenegger, Nikolaus Rajewsky, Ivano Legnini, Robert P. Zinzen
Organoids derived from stem cells become increasingly important to study human development and to model disease. However, methods are needed to control and study spatio-temporal patterns of gene expression in organoids. To this aim, we combined optog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d7ae1b7891b128f8e583e80ea3118c
http://edoc.mdc-berlin.de/21329/1/21329oa.pdf
http://edoc.mdc-berlin.de/21329/1/21329oa.pdf
Autor:
Anastasiya Boltengagen, Nikos Karaiskos, Claudia Kipar, Jonathan Alles, Salah Ayoub, Robert P. Zinzen, Christine Kocks, Nikolaus Rajewsky, Philipp Wahle
Publikováno v:
Science. 358:194-199
3D gene expression blueprint of the fly When looking at populations of cells, features such as cell heterogeneity and localization are masked. However, single-cell sequencing reveals cellular heterogeneity and rare cell types. At the onset of gastrul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67459e0d3b4ca7acdf567760a881a8e6
https://doi.org/10.1126/science.aan3235
https://doi.org/10.1126/science.aan3235
Autor:
Robert P. Zinzen, Irwin Jungreis, Philipp Wahle, Alexandra L. McCorkindale, Sascha Werner, Chinmay J. Shukla, Peter Menzel, Manolis Kellis, Irmtraud M. Meyer, Rafael A. Irizarry, John L. Rinn, Rúben Lopes Pereira Abreu
Publikováno v:
Development (Cambridge, England)
Cell type specification during early nervous system development in Drosophila melanogaster requires precise regulation of gene expression in time and space. Resolving the programs driving neurogenesis has been a major challenge owing to the complexit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce62e578bc3744ec76058c131ececb61
http://europepmc.org/articles/PMC6451322
http://europepmc.org/articles/PMC6451322
Autor:
Robert P. Zinzen, Alexandra L McCorkindale, Irmtraud M. Meyer, Stefan R. Stefanov, Peter Menzel
Publikováno v:
RNA Biology
During Drosophila melanogaster embryogenesis, tight regulation of gene expression in time and space is required for the orderly emergence of specific cell types. While the general importance of microRNAs in regulating eukaryotic gene expression has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a6cb95ce09db782010e243abfb4ac93
Autor:
Juergen A. Knoblich, Thomas Köcher, Robert P. Zinzen, Lisa Landskron, Harald Esterbauer, Elisa Rivelles, François Bonnay, Sunanjay Bajaj, Ana Veloso, Victoria Steinmann, Merve Deniz Abdusselamoglu
Publikováno v:
Cell
Summary Metabolic reprogramming is a key feature of many cancers, but how and when it contributes to tumorigenesis remains unclear. Here we demonstrate that metabolic reprogramming induced by mitochondrial fusion can be rate-limiting for immortalizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c93d2ab56a33c98fbd6826a3c8bd23
https://doi.org/10.1016/j.cell.2020.07.039
https://doi.org/10.1016/j.cell.2020.07.039
Autor:
Antje Hirsekorn, Baris Tursun, Aslihan Karabacak, Alexander Glahs, Scott A. Lacadie, Uwe Ohler, Mahmoud M. Ibrahim, Alexa Carda, Robert P. Zinzen, Ena Kolundzic
Divergent transcription from promoters and enhancers is pervasive in many species, but it remains unclear if it is a general and passive feature of all eukaryotic cis regulatory elements. To address this, we define promoters and enhancers in C. elega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c3ba25cb2b001558b0e8b1ff932f65
http://edoc.mdc-berlin.de/17569/1/17569oa.pdf
http://edoc.mdc-berlin.de/17569/1/17569oa.pdf
Autor:
Luisa Schreyer, Nikos Karaiskos, Anastasiya Boltengagen, Salah Ayoub, Samantha D. Praktiknjo, Pierre-Louis Ruffault, Stefanie Grosswendt, Carmen Birchmeier, Jonathan Alles, Christine Kocks, Nikolaus Rajewsky, Philipp Wahle, Robert P. Zinzen
Publikováno v:
BMC Biology, Vol 15, Iss 1, Pp 1-14 (2017)
BMC Biology
BMC Biology
Background Recent developments in droplet-based microfluidics allow the transcriptional profiling of thousands of individual cells in a quantitative, highly parallel and cost-effective way. A critical, often limiting step is the preparation of cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::944d65be58d8e540b18961537747fdbf
http://edoc.mdc-berlin.de/16377/1/16377oa.pdf
http://edoc.mdc-berlin.de/16377/1/16377oa.pdf