Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Robert P Weinberg"'
Autor:
Pamoda Galhenage, Yunlan Zhou, Erica Perry, Brenda Loc, Kelly Fietz, Sonia Iyer, Ferenc Reinhardt, Tiego Da Silva, Vladimir Botchkarev, Jie Chen, Christopher P. Crum, Robert A. Weinberg, Shailja Pathania
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113144- (2023)
Summary: Clinical and molecular evidence indicates that high-grade serous ovarian cancer (HGSOC) primarily originates from the fallopian tube, not the ovarian surface. However, the reasons for this preference remain unclear. Our study highlights sign
Externí odkaz:
https://doaj.org/article/fdbf18dd16e443c1a8e30ac69230764e
Autor:
Ala Jo, Allen Green, Jamie E. Medina, Sonia Iyer, Anders W. Ohman, Eric T. McCarthy, Ferenc Reinhardt, Thomas Gerton, Daniel Demehin, Ranjan Mishra, David L. Kolin, Hui Zheng, Jinwoo Cheon, Christopher P. Crum, Robert A. Weinberg, Bo R. Rueda, Cesar M. Castro, Daniela M. Dinulescu, Hakho Lee
Publikováno v:
Advanced Science, Vol 10, Iss 27, Pp n/a-n/a (2023)
Abstract Detecting early cancer through liquid biopsy is challenging due to the lack of specific biomarkers for early lesions and potentially low levels of these markers. The current study systematically develops an extracellular‐vesicle (EV)‐bas
Externí odkaz:
https://doaj.org/article/80311c6a1d4e4c65b0abe22c8b14a2e5
Autor:
Vaishnavi V. Phadnis, Jamie Snider, Venkateshwari Varadharajan, Iyappan Ramachandiran, Amy A. Deik, Zon Weng Lai, Tenzin Kunchok, Elinor Ng Eaton, Carolin Sebastiany, Anna Lyakisheva, Kyle D. Vaccaro, Juliet Allen, Zhong Yao, Victoria Wong, Betty Geng, Kipp Weiskopf, Clary B. Clish, J. Mark Brown, Igor Stagljar, Robert A. Weinberg, Whitney S. Henry
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113023- (2023)
Summary: Ferroptosis is a form of regulated cell death with roles in degenerative diseases and cancer. Excessive iron-catalyzed peroxidation of membrane phospholipids, especially those containing the polyunsaturated fatty acid arachidonic acid (AA),
Externí odkaz:
https://doaj.org/article/f1a03612f457448787c70b44eca61b6d
Autor:
Antonio E. Barberio, Sean G. Smith, Ivan S. Pires, Sonia Iyer, Ferenc Reinhardt, Mariane B. Melo, Heikyung Suh, Robert A. Weinberg, Darrell J. Irvine, Paula T. Hammond
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 2, Pp n/a-n/a (2023)
Abstract Ovarian cancer is especially deadly, challenging to treat, and has proven refractory to known immunotherapies. Cytokine therapy is an attractive strategy to drive a proinflammatory immune response in immunologically cold tumors such as many
Externí odkaz:
https://doaj.org/article/da7a5559c1a94ad19eb3527ed8b1cd25
Autor:
Bashar Hamza, Alex B. Miller, Lara Meier, Max Stockslager, Sheng Rong Ng, Emily M. King, Lin Lin, Kelsey L. DeGouveia, Nolawit Mulugeta, Nicholas L. Calistri, Haley Strouf, Christina Bray, Felicia Rodriguez, William A. Freed-Pastor, Christopher R. Chin, Grissel C. Jaramillo, Megan L. Burger, Robert A. Weinberg, Alex K. Shalek, Tyler Jacks, Scott R. Manalis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Current methods for acquiring dissemination kinetics of rare circulating tumor cells (CTCs) that form metastases have several limitations. Here, the authors show an approach for measuring endogenous CTC kinetics by continuously exchanging CTC-contain
Externí odkaz:
https://doaj.org/article/a01832348b58404486e05ba5132c7532
Autor:
Onur Aydin, Austin P. Passaro, Ritu Raman, Samantha E. Spellicy, Robert P. Weinberg, Roger D. Kamm, Matthew Sample, George A. Truskey, Jeremiah Zartman, Roy D. Dar, Sebastian Palacios, Jason Wang, Jesse Tordoff, Nuria Montserrat, Rashid Bashir, M. Taher A. Saif, Ron Weiss
Publikováno v:
APL Bioengineering, Vol 6, Iss 1, Pp 010903-010903-28 (2022)
Remarkable progress in bioengineering over the past two decades has enabled the formulation of fundamental design principles for a variety of medical and non-medical applications. These advancements have laid the foundation for building multicellular
Externí odkaz:
https://doaj.org/article/2a7183c0e02d4877b63bbb39119da369
Autor:
Ji Li, Peter S Choi, Christine L Chaffer, Katherine Labella, Justin H Hwang, Andrew O Giacomelli, Jong Wook Kim, Nina Ilic, John G Doench, Seav Huong Ly, Chao Dai, Kimberly Hagel, Andrew L Hong, Ole Gjoerup, Shom Goel, Jennifer Y Ge, David E Root, Jean J Zhao, Angela N Brooks, Robert A Weinberg, William C Hahn
Publikováno v:
eLife, Vol 7 (2018)
Alternative splicing of mRNA precursors represents a key gene expression regulatory step and permits the generation of distinct protein products with diverse functions. In a genome-scale expression screen for inducers of the epithelial-to-mesenchymal
Externí odkaz:
https://doaj.org/article/065b7c78b0bc49f4914d3e34a00422d9
Autor:
Robert P. Weinberg, Vera V. Koledova, Hyeari Shin, Jennifer H. Park, Yew Ai Tan, Anthony J. Sinskey, Ravigadevi Sambanthamurthi, ChoKyun Rha
Publikováno v:
International Journal of Alzheimer's Disease, Vol 2018 (2018)
Alzheimer’s disease is a severe neurodegenerative disease characterized by the aggregation of amyloid-β peptide (Aβ) into toxic oligomers which activate microglia and astrocytes causing acute neuroinflammation. Multiple studies show that the solu
Externí odkaz:
https://doaj.org/article/d69a3fb697954cda94d50dc4248a3233
Autor:
Juli J. Unternaehrer, Rui Zhao, Kitai Kim, Marcella Cesana, John T. Powers, Sutheera Ratanasirintrawoot, Tamer Onder, Tsukasa Shibue, Robert A. Weinberg, George Q. Daley
Publikováno v:
Stem Cell Reports, Vol 3, Iss 5, Pp 691-698 (2014)
Reprogramming of fibroblasts to induced pluripotent stem cells (iPSCs) entails a mesenchymal to epithelial transition (MET). While attempting to dissect the mechanism of MET during reprogramming, we observed that knockdown (KD) of the epithelial-to-m
Externí odkaz:
https://doaj.org/article/2ceafcf7bcea42f9b4f7de18552eddaf
Autor:
Onur Aydin, Austin P. Passaro, Ritu Raman, Samantha E. Spellicy, Robert P. Weinberg, Roger D. Kamm, Matthew Sample, George A. Truskey, Jeremiah Zartman, Roy D. Dar, Sebastian Palacios, Jason Wang, Jesse Tordoff, Nuria Montserrat, Rashid Bashir, M. Taher A. Saif, Ron Weiss
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Remarkable progress in bioengineering over the past two decades has enabled the formulation of fundamental design principles for a variety of medical and non-medical applications. These advancements have laid the foundation for building multicellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d2ae161a6feb0b749f9a327e32cd64c
https://pubmed.ncbi.nlm.nih.gov/35274072
https://pubmed.ncbi.nlm.nih.gov/35274072