Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Robert P Richter"'
Autor:
Robert P. Richter, James D. Odum, Camilla Margaroli, Jessica C. Cardenas, Lei Zheng, Kaushlendra Tripathi, Zhangjie Wang, Katelyn Arnold, Ralph D. Sanderson, Jian Liu, Jillian R. Richter
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Introduction: Heparan sulfate (HS) in the vascular endothelial glycocalyx (eGC) is a critical regulator of blood vessel homeostasis. Trauma results in HS shedding from the eGC, but the impact of trauma on HS structural modifications that could influe
Externí odkaz:
https://doaj.org/article/9239c9e753ab4de0b3413a2947abf746
Autor:
Michael John Patton, Carlos J. Orihuela, Kevin S. Harrod, Mohammad A. N. Bhuiyan, Paari Dominic, Christopher G. Kevil, Daniel Fort, Vincent X. Liu, Maha Farhat, Jonathan L. Koff, Charitharth V. Lal, Anuj Gaggar, Robert P. Richter, Nathaniel Erdmann, Matthew Might, Amit Gaggar
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-12 (2023)
Abstract Background Recent single-center reports have suggested that community-acquired bacteremic co-infection in the context of Coronavirus disease 2019 (COVID-19) may be an important driver of mortality; however, these reports have not been valida
Externí odkaz:
https://doaj.org/article/08100dfe0b7b44c1ad101bf1bafeb813
Autor:
Lece Webb, Luke Burton, Ananya Manchikalapati, Priya Prabhakaran, Jeremy M. Loberger, Robert P. Richter
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Severe acute respiratory distress syndrome in children, or PARDS, carries a high risk of morbidity and mortality that is not fully explained by PARDS severity alone. Right ventricular (RV) dysfunction can be an insidious and often under-recognized co
Externí odkaz:
https://doaj.org/article/87e910efa553437f933963178f9ad98b
Publikováno v:
Matrix Biology Plus, Vol 16, Iss , Pp 100121- (2022)
The glycocalyx attached to the apical surface of vascular endothelial cells is a rich network of proteoglycans, glycosaminoglycans, and glycoproteins with instrumental roles in vascular homeostasis. Given their molecular complexity and ability to int
Externí odkaz:
https://doaj.org/article/471aa09327b74e69b0988efda436d01f
Autor:
Robert P. Richter, Amit R. Ashtekar, Lei Zheng, Danielle Pretorius, Tripathi Kaushlendra, Ralph D. Sanderson, Amit Gaggar, Jillian R. Richter
Publikováno v:
JCI Insight, Vol 7, Iss 15 (2022)
Angiopoietin-2 (Ang-2) is a key mediator of vascular disease during sepsis, and elevated plasma levels of Ang-2 are associated with organ injury scores and poor clinical outcomes. We have previously observed that biomarkers of endothelial glycocalyx
Externí odkaz:
https://doaj.org/article/09c6efd531964cad857260ed54088102
Autor:
Robert P. Richter, Gregory A. Payne, Namasivayam Ambalavanan, Amit Gaggar, Jillian R. Richter
Publikováno v:
Matrix Biology Plus, Vol 14, Iss , Pp 100106- (2022)
The vascular endothelium is the interface between circulating blood and end organs and thus has a critical role in preserving organ function. The endothelium is lined by a glycan-rich glycocalyx that uniquely contributes to endothelial function throu
Externí odkaz:
https://doaj.org/article/1aeae2cd1a314c989f7309dc5a7429f6
Autor:
Robert P. Richter, MD, Danielle M. Joiner, BS, Russell L. Griffin, PhD, Jan O. Jansen, MBBS, PhD, Jeffrey D. Kerby, MD, PhD, Charles E. Wade, PhD, John B. Holcomb, MD, Jessica C. Cardenas, PhD, Jillian R. Richter, PhD
Publikováno v:
Annals of Surgery Open, Vol 3, Iss 1, p e116 (2022)
Objectives:. Determine associations between biomarkers of endotheliopathy, 24-hour fibrinolysis phenotypes and clinical outcomes after trauma. Background:. The vascular endothelium is a critical regulator of hemostasis and organ function. The relatio
Externí odkaz:
https://doaj.org/article/fc7da8c476d14c23a29a9cf5ccca69b0
Autor:
Jan O. Jansen, Amit R. Ashtekar, Robert P. Richter, Jeffrey D. Kerby, Jillian R. Richter, Lei Zheng, Shannon C Walker
Publikováno v:
Shock
INTRODUCTION Acute traumatic coagulopathy (ATC) is an endogenous impairment in hemostasis that often contributes to early mortality after trauma. Endothelial glycocalyx damage is associated with trauma-induced coagulation abnormalities; however, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97103d3f99eab44b6cc7f339de108d2c
https://doi.org/10.1097/shk.0000000000001867
https://doi.org/10.1097/shk.0000000000001867
Autor:
Jeremy M Loberger, Kristen C Waddell, Priya Prabhakaran, Ryan M Jones, Maggie V Lawrence, Leah A Bittles, Amy M Hill, Shannon E O’Sheal, Andrea W Armstrong, Christy L Thomas, Laura H Daniel, Nancy M Tofil, William C Sasser, Robert P Richter, Chrystal L Rutledge
Publikováno v:
Respiratory care. 67(11)
Recent studies reported that children on mechanical ventilation who were managed with an analgosedation approach and standardized extubation readiness testing experienced better outcomes, including decreased delirium and invasive mechanical ventilati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d088249143ad137cf177fc35c33cd3
https://pubmed.ncbi.nlm.nih.gov/36266058
https://pubmed.ncbi.nlm.nih.gov/36266058
Autor:
Robert P. Richter, Danielle M. Joiner, Russell L. Griffin, Jan O. Jansen, Jeffrey D. Kerby, Charles E. Wade, John B. Holcomb, Jessica C. Cardenas, Jillian R. Richter
Publikováno v:
Ann Surg Open
OBJECTIVES: Determine associations between biomarkers of endotheliopathy, 24-hour fibrinolysis phenotypes and clinical outcomes after trauma. BACKGROUND: The vascular endothelium is a critical regulator of hemostasis and organ function. The relations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f59d74e8852760d7e1d48abcc728e04
https://europepmc.org/articles/PMC9187295/
https://europepmc.org/articles/PMC9187295/
