Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Robert P Doyle"'
Autor:
James E. Blevins, Mackenzie K. Honeycutt, Jared D. Slattery, Matvey Goldberg, June R. Rambousek, Edison Tsui, Andrew D. Dodson, Kyra A. Shelton, Therese S. Salemeh, Clinton T. Elfers, Kylie S. Chichura, Emily F. Ashlaw, Sakeneh Zraika, Robert P. Doyle, Christian L. Roth
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
We recently reported that a novel chimeric peptide (GEP44) targeting both the glucagon-like peptide-1 receptor (GLP-1R) and neuropeptide Y1- and Y2 receptor (Y1R and Y2R) reduced energy intake and body weight (BW) in diet-induced obese (DIO) rats. We
Externí odkaz:
https://doaj.org/article/529ad7d0cfa24b59b26ce81122b9ef1b
Autor:
Kylie S. Chichura, Clinton T. Elfers, Therese S. Salameh, Varun Kamat, Oleg G. Chepurny, Aelish McGivney, Brandon T. Milliken, George G. Holz, Sarah V. Applebey, Matthew R. Hayes, Ian R. Sweet, Christian L. Roth, Robert P. Doyle
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Mechanisms underlying long-term sustained weight loss and glycemic normalization after obesity surgery include changes in gut hormone levels, including glucagon-like peptide 1 (GLP-1) and peptide YY (PYY). We demonstrate that two peptide bia
Externí odkaz:
https://doaj.org/article/dc106d853e6f471fa38cee689f96ea30
Publikováno v:
ACS Omega, Vol 6, Iss 49, Pp 33454-33461 (2021)
Externí odkaz:
https://doaj.org/article/da1fd468765044e7a693b9b4c2ca4719
Publikováno v:
ACS Omega, Vol 6, Iss 44, Pp 29713-29723 (2021)
Externí odkaz:
https://doaj.org/article/457a9ea64286437caf0fac9f66a16a7c
Autor:
Chase H. Smith, Nathan A. Johnson, Clinton R. Robertson, Robert D. Doyle, Charles R. Randklev
Publikováno v:
Ecology and Evolution, Vol 11, Iss 16, Pp 11102-11122 (2021)
Abstract Population genomics has significantly increased our ability to make inferences about microevolutionary processes and demographic histories, which have the potential to improve protection and recovery of imperiled species. Freshwater mussels
Externí odkaz:
https://doaj.org/article/356ab905b05e4391aeb6ee67f6f725e4
Autor:
Benjamin C. Reiner, Richard C. Crist, Tito Borner, Robert P. Doyle, Matthew R. Hayes, Bart C. De Jonghe
Publikováno v:
Molecular Metabolism, Vol 56, Iss , Pp 101422- (2022)
Objective: Growth differentiation factor 15 (GDF15) is known to play a role in feeding, nausea, and body weight, with action through the GFRAL-RET receptor complex in the area postrema (AP) and nucleus tractus solitarius (NTS). To further elucidate t
Externí odkaz:
https://doaj.org/article/6f6cbabc2b6a49a58d1c61626c1bfb87
Publikováno v:
Results in Chemistry, Vol 4, Iss , Pp 100274- (2022)
The reaction of glycylglycine (H2GG) with zinc oxide in a 2:1 ratio in water produced [Zn2(HGG1-)4(H2O)2] in high yield. The compound was characterized by elemental analysis, thermogravimetric analysis/differential scanning calorimetry, and FTIR spec
Externí odkaz:
https://doaj.org/article/cd9e6b406fa94f7f91d0d471ce208fce
Autor:
Tito Borner, Jayme L. Workinger, Ian C. Tinsley, Samantha M. Fortin, Lauren M. Stein, Oleg G. Chepurny, George G. Holz, Aleksandra J. Wierzba, Dorota Gryko, Ebba Nexø, Evan D. Shaulson, Ankur Bamezai, Valentina A. Rodriguez Da Silva, Bart C. De Jonghe, Matthew R. Hayes, Robert P. Doyle
Publikováno v:
Cell Reports, Vol 31, Iss 11, Pp 107768- (2020)
Summary: Glucagon-like peptide-1 receptor (GLP-1R) agonists used to treat type 2 diabetes mellitus often produce nausea, vomiting, and in some patients, undesired anorexia. Notably, these behavioral effects are caused by direct central GLP-1R activat
Externí odkaz:
https://doaj.org/article/e5149ea465c3458cb9a6f4de1b3228fc
Autor:
Jay Tinklepaugh, Britannia M. Smith, Etta Hanlon, Chloe Zubieta, Fadi Bou-Abdallah, Robert P. Doyle
Publikováno v:
ACS Omega, Vol 2, Iss 10, Pp 7141-7145 (2017)
Externí odkaz:
https://doaj.org/article/7b259226a0c34d949f8c5761720d842c
Autor:
Akhila N. W. Kuda-Wedagedara, Jayme L. Workinger, Ebba Nexo, Robert P. Doyle, Nerissa Viola-Villegas
Publikováno v:
ACS Omega, Vol 2, Iss 10, Pp 6314-6320 (2017)
Externí odkaz:
https://doaj.org/article/1ab1d0ad7bb14ae4bf29d0d72985e312