Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Robert P, Mohney"'
Autor:
Makoto Harada, Jonathan Adam, Marcela Covic, Jianhong Ge, Stefan Brandmaier, Caroline Muschet, Jialing Huang, Siyu Han, Martina Rommel, Markus Rotter, Margit Heier, Robert P. Mohney, Jan Krumsiek, Gabi Kastenmüller, Wolfgang Rathmann, Zhongmei Zou, Sven Zukunft, Markus F. Scheerer, Susanne Neschen, Jerzy Adamski, Christian Gieger, Annette Peters, Donna P. Ankerst, Thomas Meitinger, Tanya L. Alderete, Martin Hrabe de Angelis, Karsten Suhre, Rui Wang-Sattler
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Background Metformin and sodium-glucose-cotransporter-2 inhibitors (SGLT2i) are cornerstone therapies for managing hyperglycemia in diabetes. However, their detailed impacts on metabolic processes, particularly within the citric acid (TCA) c
Externí odkaz:
https://doaj.org/article/5843fb532be04b438b4aad8078618b3c
Autor:
Patrick Weinisch, Johannes Raffler, Werner Römisch-Margl, Matthias Arnold, Robert P. Mohney, Manuela J. Rist, Cornelia Prehn, Thomas Skurk, Hans Hauner, Hannelore Daniel, Karsten Suhre, Gabi Kastenmüller
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114416- (2024)
Summary: Metabolism oscillates between catabolic and anabolic states depending on food intake, exercise, or stresses that change a multitude of metabolic pathways simultaneously. We present the HuMet Repository for exploring dynamic metabolic respons
Externí odkaz:
https://doaj.org/article/e3d1619441524c1aa6797b3a00c4a797
Autor:
Cristina Menni, Jialing Zhu, Caroline I Le Roy, Olatz Mompeo, Kristin Young, Casey M. Rebholz, Elizabeth Selvin, Kari E. North, Robert P Mohney, Jordana T Bell, Eric Boerwinkle, Tim D Spector, Massimo Mangino, Bing Yu, Ana M Valdes
Publikováno v:
Gut Microbes, Vol 11, Iss 6, Pp 1632-1642 (2020)
Type 2 diabetes (T2D) is associated with reduced gut microbiome diversity, although the cause is unclear. Metabolites generated by gut microbes also appear to be causative factors in T2D. We therefore searched for serum metabolites predictive of gut
Externí odkaz:
https://doaj.org/article/09df21ff4f3747d3aebe8eb0d2d893b5
Autor:
Alessia Visconti, Caroline I. Le Roy, Fabio Rosa, Niccolò Rossi, Tiphaine C. Martin, Robert P. Mohney, Weizhong Li, Emanuele de Rinaldis, Jordana T. Bell, J. Craig Venter, Karen E. Nelson, Tim D. Spector, Mario Falchi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Here, the authors study the interplay between the microbiome and faecal and blood metabolome, and how the microbiome interacts in the dialogue between these metabolic compartments, identifying a key role for microbial functions and underscoring their
Externí odkaz:
https://doaj.org/article/6e4760dc3fb74abf8d3ad1ef4140fbd0
Autor:
January Weiner, Jeroen Maertzdorf, Jayne S. Sutherland, Fergal J. Duffy, Ethan Thompson, Sara Suliman, Gayle McEwen, Bonnie Thiel, Shreemanta K. Parida, Joanna Zyla, Willem A. Hanekom, Robert P. Mohney, W. Henry Boom, Harriet Mayanja-Kizza, Rawleigh Howe, Hazel M. Dockrell, Tom H. M. Ottenhoff, Thomas J. Scriba, Daniel E. Zak, Gerhard Walzl, Stefan H. E. Kaufmann, The GC6-74 consortium
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
The tuberculosis pandemic requires new methods for diagnosing and containing infections prior to active disease. Here, the authors performed a multi-site observational study within sub-Saharan Africa and present serum and plasma metabolic signatures
Externí odkaz:
https://doaj.org/article/05ed44b4c9294316afa2b3d18f1beb1a
Autor:
Sweety Mathew, Anna Halama, Sara Abdul Kader, Minkyung Choe, Robert P. Mohney, Joel A. Malek, Karsten Suhre
Publikováno v:
Journal of Functional Foods, Vol 49, Iss , Pp 267-276 (2018)
Date fruits are rich in phytochemicals that have anti-oxidative properties and are therefore considered as functional foods. However, it is unclear which part of the date metabolites actually enter the blood stream and remain bioavailable to exert an
Externí odkaz:
https://doaj.org/article/9626d69958d84fa7853399d3c6e20fd1
Autor:
Pirro G. Hysi, Massimo Mangino, Paraskevi Christofidou, Mario Falchi, Edward D. Karoly, NIHR Bioresource Investigators, Robert P. Mohney, Ana M. Valdes, Tim D. Spector, Cristina Menni
Publikováno v:
Metabolites, Vol 12, Iss 1, p 61 (2022)
Metabolites are small products of metabolism that provide a snapshot of the wellbeing of an organism and the mechanisms that control key physiological processes involved in health and disease. Here we report the results of a genome-wide association s
Externí odkaz:
https://doaj.org/article/b4505b4d8e4e49bc8fe4cd8dead44463
Autor:
Noha A. Yousri, Khalid A. Fakhro, Amal Robay, Juan L. Rodriguez-Flores, Robert P. Mohney, Hassina Zeriri, Tala Odeh, Sara Abdul Kader, Eman K. Aldous, Gaurav Thareja, Manish Kumar, Alya Al-Shakaki, Omar M. Chidiac, Yasmin A. Mohamoud, Jason G. Mezey, Joel A. Malek, Ronald G. Crystal, Karsten Suhre
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Blood metabolites are influenced by a combination of genetic and environmental factors. Here, Yousri and colleagues perform a whole-exome sequencing study in combination with a metabolomics analysis to identify metabolic quantitative trait loci in a
Externí odkaz:
https://doaj.org/article/c31de4379d5747af8230fd50df05087b
Autor:
Noha A. Yousri, Karim Bayoumy, Wessam Gad Elhaq, Robert P. Mohney, Samar Al Emadi, Mohammed Hammoudeh, Hussein Halabi, Basel Masri, Humeira Badsha, Imad Uthman, Robert Plenge, Richa Saxena, Karsten Suhre, Thurayya Arayssi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Recent metabolomics studies of Rheumatoid Arthritis (RA) reported few metabolites that were associated with the disease, either due to small cohort sizes or limited coverage of metabolic pathways. Our objective is to identify metabolites ass
Externí odkaz:
https://doaj.org/article/ba383362ef77417ab01af14566d56760
Caloric Restriction Alters Postprandial Responses of Essential Brain Metabolites in Young Adult Mice
Autor:
Lucille M. Yanckello, Lyndsay E. A. Young, Jared D. Hoffman, Robert P. Mohney, Mignon A. Keaton, Erin Abner, Ai-Ling Lin
Publikováno v:
Frontiers in Nutrition, Vol 6 (2019)
Caloric restriction (CR) has been shown to extend longevity and protect brain function in aging. However, the effects of CR in young adult mice remain largely unexplored. In addition to the fundamental, long-term changes, recent studies demonstrate t
Externí odkaz:
https://doaj.org/article/60c0b33376b64bbcb93538a33333c88f