Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Robert Orchard"'
Publikováno v:
bioRxiv
Non-enveloped viruses require cell lysis to release new virions from infected cells, suggesting that these viruses require mechanisms to induce cell death. Noroviruses are one such group of viruses, but a mechanism of norovirus-infection triggered ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6c689d64fb31c00949c2bd96c33b94
https://europepmc.org/articles/PMC10055165/
https://europepmc.org/articles/PMC10055165/
Autor:
Emily A. Rex, Dahee Seo, Sruthi Chappidi, Chelsea Pinkham, Sabrynna Brito Oliveira, Aaron Embry, David Heisler, Yang Liu, Karolin Luger, Neal M. Alto, Flávio Guimarães da Fonseca, Robert Orchard, Dustin Hancks, Don B. Gammon
Publikováno v:
bioRxiv
The FACT complex is an ancient chromatin remodeling factor comprised of Spt16 and SSRP1 subunits that regulates specific eukaryotic gene expression programs. However, whether FACT regulates host immune responses to infection was unclear. Here, we ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7687a2c50bfb670e01549ef937f5251
https://doi.org/10.1101/2023.02.08.527673
https://doi.org/10.1101/2023.02.08.527673
Autor:
Jennifer Martinez, Larissa D. Cunha, Sunmin Park, Mao Yang, Qun Lu, Robert Orchard, Quan-Zhen Li, Mei Yan, Laura Janke, Cliff Guy, Andreas Linkermann, Herbert W. Virgin, Douglas R. Green
Publikováno v:
Nature. 609:640-640
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70cd52b31b8ff653dd759895a8553c38
https://doi.org/10.1038/s41586-022-05201-2
https://doi.org/10.1038/s41586-022-05201-2
Publikováno v:
Genetic and Evolutionary Computation: Medical Applications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4e1571fee167075ab86767f3e58b0cc
https://doi.org/10.1002/9780470973134.ch9
https://doi.org/10.1002/9780470973134.ch9
Autor:
Jennifer, Martinez, Larissa D, Cunha, Sunmin, Park, Mao, Yang, Qun, Lu, Robert, Orchard, Quan-Zhen, Li, Mei, Yan, Laura, Janke, Cliff, Guy, Andreas, Linkermann, Herbert W, Virgin, Douglas R, Green
Publikováno v:
Nature
Defects in clearance of dying cells have been proposed to underlie the pathogenesis of systemic lupus erythematosus (SLE). Mice lacking molecules associated with dying cell clearance develop SLE-like disease, and phagocytes from patients with SLE oft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff160f596a3850d14311fceb5a6acb2c
https://pubmed.ncbi.nlm.nih.gov/36045298
https://pubmed.ncbi.nlm.nih.gov/36045298
Publikováno v:
IJCNN
A neural network classifier is sought. Classical neural network neurons are aggregations of a weight multiplied by an input value and then controlled via an activation function. This paper learns everything within the neuron using a variant of geneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4bcf88ba8537ea7acc3b1b94054e31
https://nrc-publications.canada.ca/eng/view/object/?id=be2de4a7-2607-4098-ac65-58bda4081cdd
https://nrc-publications.canada.ca/eng/view/object/?id=be2de4a7-2607-4098-ac65-58bda4081cdd
Publikováno v:
Neural networks : the official journal of the International Neural Network Society. 22(5-6)
Classical neural networks are composed of neurons whose nature is determined by a certain function (the neuron model), usually pre-specified. In this paper, a type of neural network (NN-GP) is presented in which: (i) each neuron may have its own neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7150de9d20db0fd5362218e71f03812
https://pubmed.ncbi.nlm.nih.gov/19604672
https://pubmed.ncbi.nlm.nih.gov/19604672
Publikováno v:
IJCNN
Computational intelligence and other data mining techniques are used for characterizing regional and time varying climatic variations in Spain in the period 1901-2005. Daily maximum temperature data from 10 climatic stations are analyzed (with and wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1551f5a824b1d14ed2987d6feda34dde
https://nrc-publications.canada.ca/eng/view/object/?id=aea64c25-fd0f-4673-9dbd-7534d1db7a11
https://nrc-publications.canada.ca/eng/view/object/?id=aea64c25-fd0f-4673-9dbd-7534d1db7a11
Publikováno v:
Machine Learning and Data Mining in Pattern Recognition ISBN: 9783540405047
MLDM
MLDM
Automatically authoring or acquiring cases in the case-based reasoning (CBR) systems is recognized as a bottleneck issue that can determine whether a CBR system will be successful or not. In order to reduce human effort required for authoring the cas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e1b4a0eb8a22277fc04e89851d9603f
https://doi.org/10.1007/3-540-45065-3_12
https://doi.org/10.1007/3-540-45065-3_12