Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Robert O. Warwick"'
Autor:
Steve J. Offord, Robert O. Warwick
Publikováno v:
European Journal of Pharmacology. 104:379-382
Ketanserin, a serotonin2 receptor antagonist, evoked a dose-related non-calcium dependent release of tritium from slices of rat hypothalamus preloaded with [3H]serotonin. Concentrations of 1, 5 and 10 microM ketanserin caused a 0.5%, 64% and 110% inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09c41a97c926f37651291f9ce887ca7
https://doi.org/10.1016/0014-2999(84)90417-5
https://doi.org/10.1016/0014-2999(84)90417-5
Autor:
Robert O. Warwick, Bruce A. Donzanti
Publikováno v:
European Journal of Pharmacology. 59:107-110
In vitro effects of d,l-methadone and morphine on [3H]serotonin (3H-5-HT) uptake in rat periaqueductal gray (PAG) slices were investigated. Only methadone had a significant inhibitory effect on 3H-5-HT uptake which was significantly enhanced by nalox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d0346ec343586472c1b5eb5af176a9
https://doi.org/10.1016/0014-2999(79)90030-x
https://doi.org/10.1016/0014-2999(79)90030-x
Publikováno v:
Life Sciences. 37:775-782
Intravenous administration of digitoxigenin (DTXGN) evokes seizure episodes in mice which may be dependent on brain biogenic amines such as serotonin (5-HT). Fasting is known to have effects on both drug toxicity and brain 5-HT synthesis. The purpose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::815678e864bf596aa4558c392da339ce
https://doi.org/10.1016/0024-3205(85)90548-x
https://doi.org/10.1016/0024-3205(85)90548-x
Autor:
R.Craig Schnell, Robert O. Warwick
Publikováno v:
European Journal of Pharmacology. 38:329-335
Experiments were conducted to determine if the acute hypothermia elicited by morphine in the rat resulted from morphine-induced inhibition of serotonin reuptake into hypothalamic nerve-endings. The acute hypothermia elicited by morphine (30 mg/kg, s.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7c078ef929d837637e8cbbe14f36bf
https://doi.org/10.1016/0014-2999(76)90336-8
https://doi.org/10.1016/0014-2999(76)90336-8
Publikováno v:
Pharmacology. 15:415-427
The effect of morphine on uptake of serotonin into hypothalamic synaptosomes was determined following acute and chronic morphine treatment in the rat. The uptake of serotonin was noncompetitively inhibited by in vitro morphine (IC50 = 7 X 10(-4) M) b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d29d6b170bee88da7705ecbbace430a7
https://doi.org/10.1159/000136718
https://doi.org/10.1159/000136718
Autor:
Michael S. Saporito, Robert O. Warwick
Publikováno v:
Life sciences. 45(1)
We investigated the activity of bombesin (BN), neuromedin-C (NM-C) and neuromedin-B (NM-B) on serotonin (5-HT) release and reuptake in rat hypothalamus (HYP) in vitro . BN and NM-C but not NM-B (all 1 μM) decreased K + evoked 3 H-5-HT release from s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c7d8190a864551a98acbbc740497ad
https://pubmed.ncbi.nlm.nih.gov/2545989
https://pubmed.ncbi.nlm.nih.gov/2545989
Autor:
Steve J. Offord, Robert O. Warwick
Publikováno v:
Pharmacology, biochemistry, and behavior. 26(3)
Serotonin (5-HT) activity in vivo and in vitro was evaluated in rats following acute and chronic administration of the antidepressants nialamide (NMD) and clomipramine (CMI). The 5-HT motor syndrome was used as an index of in vivo serotonergic functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f690b5c59f06c019d89d2f0f25763ed
https://pubmed.ncbi.nlm.nih.gov/2437597
https://pubmed.ncbi.nlm.nih.gov/2437597
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Publikováno v:
Pharmacology; 1977, Vol. 15 Issue 5, p415-427, 13p