Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Robert O. Messing"'
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The central amygdala (CeA) contains a diverse population of cells, including multiple subtypes of GABAergic neurons, along with glia and epithelial cells. Specific CeA cell types have been shown to affect alcohol consumption in animal models
Externí odkaz:
https://doaj.org/article/95f0b34f48f645bd9f6ab1971fa8d1c3
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Alcohol use disorder (AUD) is highly prevalent and one of the leading causes of disability in the US and around the world. There are some molecular biomarkers of heavy alcohol use and liver damage which can suggest AUD, but these are lacking in sensi
Externí odkaz:
https://doaj.org/article/d68be69375a94822afbf26733d7c1e1c
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 2 (2022)
Alcohol Use Disorder (AUD) is a chronic, relapsing syndrome diagnosed by a heterogeneous set of behavioral signs and symptoms. There are no laboratory tests that provide direct objective evidence for diagnosis. Microarray and RNA-Seq technologies ena
Externí odkaz:
https://doaj.org/article/e082e1a535da4390b59c3cebf457e826
Autor:
Giordano de Guglielmo, Marsida Kallupi, Matthew B. Pomrenze, Elena Crawford, Sierra Simpson, Paul Schweitzer, George F. Koob, Robert O. Messing, Olivier George
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Withdrawal from alcohol activates neurons in the central amygdala (CeA) and increases craving for alcohol. The authors show that these neurons predominantly express CRF and project to the BNST. Inactivation of this pathway reduces the dependence-rela
Externí odkaz:
https://doaj.org/article/8db57a0776314be7af8485f7e6d97794
Autor:
Matthew B. Pomrenze, Simone M. Giovanetti, Rajani Maiya, Adam G. Gordon, Lauren J. Kreeger, Robert O. Messing
Publikováno v:
Cell Reports, Vol 29, Iss 1, Pp 13-21.e4 (2019)
Summary: Central amygdala (CeA) neurons that produce corticotropin-releasing factor (CRF) regulate anxiety and fear learning. These CeACRF neurons release GABA and several neuropeptides predicted to play important yet opposing roles in these behavior
Externí odkaz:
https://doaj.org/article/caf79e3179684d8d85ebf6a591d21990
Autor:
Matthew B Pomrenze, E Zayra Millan, F. Woodward Hopf, Ronald eKeiflin, Rajani eMaiya, Angelo eBlasio, Jahan eDadgar, Viktor eKharazia, Giordano eDe Guglielmo, Elena eCrawford, Patricia H. Janak, Olivier eGeorge, Kenner C. Rice, Robert O. Messing
Publikováno v:
Frontiers in Neuroscience, Vol 9 (2015)
Corticotrophin-releasing factor (CRF) is a 41 amino acid neuropeptide that coordinates adaptive responses to stress. CRF projections from neurons in the central nucleus of the amygdala (CeA) to the brainstem are of particular interest for their role
Externí odkaz:
https://doaj.org/article/8a11322451a04110bf704ab01cc4fe68
Autor:
Peisen Zhao, Sudip Mondal, Chris Martin, Andrew DuPlissis, Shahab Chizari, Ke-Yue Ma, Rajani Maiya, Robert O. Messing, Ning Jiang, Adela Ben-Yakar
Publikováno v:
Nature Methods. 20:590-599
Autor:
Michael P. Dugan, Laura B. Ferguson, Nicholas T. Hertz, Robert J. Chalkley, Alma L. Burlingame, Kevan M. Shokat, Peter J. Parker, Robert O. Messing
Publikováno v:
Molecular & cellular proteomics : MCP, vol 22, iss 4
Mol Cell Proteomics
Mol Cell Proteomics
Protein kinase C epsilon (PKCε) plays important roles in behavioral responses to alcohol and in anxiety-like behavior in rodents, making it a potential drug target for reducing alcohol consumption and anxiety. Identifying signals downstream of PKCε
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fab9ce87ea8b634bfa042889711baa16
https://escholarship.org/uc/item/5jw1n92s
https://escholarship.org/uc/item/5jw1n92s
Autor:
Bryan Cruz, Ryan Bullard, Valentina Vozella, Vittoria Borgonetti, Paula C. Bianchi, Dean Kirson, Michal Bajo, Robert O. Messing, Eric P. Zorrila, Marisa Roberto
Publikováno v:
Alcohol. 109:84
Publikováno v:
Neuropharmacology. 231:109508