Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Robert O. Kerr"'
Autor:
Elin Rowen, Min-Young Lee, Nikolai A. Podoltsev, Jin-Won Kwon, Muhammad Wasif Saif, Robert O. Kerr, Jaewon Yu, Jose A. Figueroa, Mark S. Rubin
Publikováno v:
Cancer Investigation. 28:186-194
To determine in patients, with locally advanced or metastatic pancreatic cancer (APC), efficacy and safety of treatment with intravenous paclitaxel loaded polymeric micelle (GPM).This was a multicenter, open-label Phase II study. Patients with APC, E
Autor:
Robert O. Kerr, William J. Tester
Publikováno v:
Clinical Drug Investigation. 19:25-32
Objective: To compare pain control, patient preference and tolerability for two extended-release ® capsules (administered once daily) and MS Contin® tablets (administered twice daily), in the treatment of chronic cancer pain.
Autor:
Roberta Bowles, William J. Tester, Peter Hodsman, Carlo Maccarrone, Patrick O'Meara, Alan Broomhead, Robert O. Kerr
Publikováno v:
Journal of Pain and Symptom Management. 14:63-73
Kadian/Kapanol (K) is a capsule formulation of morphine designed for 12- or 24-hourly dosing. This double-blind study compared the efficacy and safety of K every 24 hr to K every 12 hr and MS Contin tablets (MSC) every 12 hr. One hundred fifty-two pa
Autor:
Robert O. Kerr, Jesus G. Berdeja, Philip Kuriakose, Jennifer H Black, Asha Surendranathan, Francesco Turturro, Arthur E. Frankel
Publikováno v:
Blood. 104:4824-4824
Therapeutic options for chronic lymphocytic leukemia (CLL) at relapse are limited because of myelosuppressive toxicity. Denileukin diftitox (ONTAK®, Ligand Pharmaceuticals) is a genetically engineered fusion protein comprising the enzymatically acti
Autor:
Elber S. Camacho, Andres Forero-Torres, Pratik S. Multani, Richard van der Jagt, Jonathan W. Friedberg, K. Sue Robinson, Brent Roeck, Robert O. Kerr, John D. Hainsworth, Philip Cohen
Publikováno v:
Blood. 104:2480-2480
SDX-105 (Treanda™, Bendamustine HCl) is an alkylating agent that may exert its anti-tumor activity via mitotic catastrophe, an apoptosis-independent cell-death pathway, as well as, through apoptosis. Its cytotoxic potency is unattenuated in chemoth
Publikováno v:
European Journal of Cancer. 31:S182
Although oral morphine remains the opioid of choice for the management of moderate to severe cancer pain, controlled-release morphine fonnulations have only enabled dosing every 8 to 12 hours. Kadian™/Kapanol™ (K) is novel polymer-coated morphine
Autor:
Gerald M. Koppes, Robert O. Kerr
Publikováno v:
Military Medicine. 143:285-287
Publikováno v:
Medical and pediatric oncology. 4(2)
Three patients with Hodgkin disease, eight with non-Hodgkin lymphoma, and one with chronic lymphocytic leukemia refractory to conventional combination chemotherapy were treated for remission induction with a new kinetically designed four-drug combina
Publikováno v:
The New England journal of medicine. 287(26)
Antiglobulin testing revealed IgG, C3, C4 and C5 on the erythrocytes in a case of penicillin-induced, immune hemolytic anemia. When no penicillin was in the patient's serum, the survival times of autologous and of normal erythrocytes, measured concom
Publikováno v:
The Journal of Immunology. 107:1209-1210
Summary In four patients with autoimmune hemolytic anemia, antiglobulin testing revealed, in addition to IgG, C3 and C4, erythrocyte-bound C5 and C6. In the presence of fresh serum, Rh-antiserum Ripley also caused non-lytic binding of C3, C4, C5 and