Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Robert O. Bash"'
Autor:
Arlynn F. Mulne, Gail E. Tomlinson, Victor M. Aquino, Daniel C. Bowers, Naomi J. Winick, Heidi J. Haynes, Janna M. Journeycake, Robert O. Bash, Patrick J. Leavey
Publikováno v:
Pediatric Blood & Cancer. 42:93-98
Background. To determine the maximumtolerated duration and dose-limiting toxicity of a daily schedule of orally administered cyclophosphamide and topotecan in pediatric patients with recurrent or refractory malignant solid tumors. Methods. Patients r
Autor:
Eleonora Hansch, Raymond Quigley, Gerald S. Arbus, Jeffrey M. Saland, Patrick J. Leavey, Robert O. Bash
Publikováno v:
Pediatric Nephrology. 17:825-829
The purpose of the present study was to examine the clearance of methotrexate (MTX) by high-flux hemodialysis (HD) in pediatric oncology patients. We present three patients who experienced nephrotoxicity and prolonged exposure to toxic MTX concentrat
Publikováno v:
Leukemia. 14:1215-1224
The identification of prognostic parameters and surrogate markers for defining patient risk has been beneficial in effectively guiding therapy and increasing the survival of leukemia patients. It has been hypothesized that the therapeutic response, a
Autor:
Mary V. Relling, Robert O. Bash, Susana C. Raimondi, Naomi J. Winick, Michael D. Amylon, Barton A. Kamen, Bruce M. Camitta, C. Chen, Jonathan J. Shuster, Michael H. Woo, Carolyn A. Felix, Frederick G. Behm, Ching-Hon Pui
Publikováno v:
Leukemia. 14:232-237
Epipodophyllotoxin-associated secondary myeloid leukemia is a devastating complication of acute lymphoblastic leukemia (ALL) therapy. The risk factors for treatment-related myeloid leukemia remain incompletely defined. Genetic deficiencies in glutath
Publikováno v:
The American Journal of Pathology. 154:1023-1035
The presence of occult disease in cancer patients after therapy is one of the major problems faced by oncologists. For example, although 95% of pediatric T-cell acute lymphoblastic leukemia (T-ALL) patients have a complete therapeutic response to mul
Autor:
William M. Crist, RG Smith, Robert O. Bash, S Hall, Richard Baer, Michael D. Amylon, Charles F. Timmons
Publikováno v:
Blood. 86:666-676
Almost 25% of patients with T-cell acute lymphoblastic leukemia (T-ALL) have tumor-specific rearrangements of the TAL1 gene. Although TAL1 expression has not been observed in normal lymphocytes, TAL1 gene products are readily detected in leukemic cel
Publikováno v:
Cancer. 74:189-196
Background. Standard treatment for fever during periods of chemotherapy-induced neutropenia includes hospitalization and administration of intravenous antibiotics until the patient is afebrile and no longer neutropenic. This study prospectively evalu
Publikováno v:
Clinical Immunology Newsletter. 14:33-37
Autor:
J Pullen, AJ Carroll, Jonathan J. Shuster, Michael D. Amylon, William M. Crist, Robert O. Bash, Michael P. Link, Richard Baer, George R. Buchanan, RG Smith
Publikováno v:
Blood. 81:2110-2117
Alteration of the TAL1 locus is the most common nonrandom genetic defect in childhood T-cell acute lymphoblastic leukemia (T-ALL). To determine if rearrangements of the TAL1 proto-oncogene confer a distinct leukemic phenotype, we studied leukemic per
Publikováno v:
Cancer. 68:940-943
A routine admission chest radiograph (CXR) in pediatric patients with cancer who are admitted to the hospital for fever and neutropenia has been advised because the signs and symptoms of pneumonia may be absent. The authors studied 131 consecutive pa