Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Robert O Baker"'
Autor:
Douglas W. Grosenbach, Trevor Brasel, Andrew G Cawthon, Philip J. Kuehl, Erin S. Reynolds, Dennis E. Hruby, Robert O Baker, Andrew T Russo, Victoria Sugita, Tara Bailey, Krystle N. Agans
Publikováno v:
The Journal of Infectious Diseases. 218:1490-1499
Background Tecovirimat (ST-246) is being developed as an antiviral therapeutic for smallpox for use in the event of an accidental or intentional release. The last reported case of smallpox was 1978 but the potential for use of variola virus for biowa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c44eb1eee7a317b0863bf927427ff4
https://doi.org/10.1093/infdis/jiy326
https://doi.org/10.1093/infdis/jiy326
Autor:
Daniel C. Pevear, Guang Yang, Kem Waller, Erik Declercq, Robert O. Baker, Marc H. Davies, Barone Linda, Erin Touchette, Gerry Rhodes, R. L. Mark Buller, Sanjeev Tohan, John W. Huggins, Kevin F. Jones, Dennis E. Hruby, Thomas R. Bailey, Johan Neyts, Robert Jordan, Christopher J. Burns, Marc S. Collett, Jill Schriewer, Susan Rippen
Publikováno v:
Journal of Virology. 79:13139-13149
ST-246 is a low-molecular-weight compound (molecular weight = 376), that is potent (concentration that inhibited virus replication by 50% = 0.010 μM), selective (concentration of compound that inhibited cell viability by 50% = >40 μM), and active a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc7e6119d794f1a5332430187e6ff79
https://doi.org/10.1128/jvi.79.20.13139-13149.2005
https://doi.org/10.1128/jvi.79.20.13139-13149.2005
Autor:
Eric M. Mucker, John W. Huggins, Rafael Herrera, David A. Kulesh, David A. Norwood, Bonnie M. Loveless, David M. Miller, Robert O. Baker, Susan H. Zwiers, Chris Hartmann, Peter B. Jahrling, Leonard P. Wasieloski, Deanna R. Christensen
Publikováno v:
Journal of Clinical Microbiology. 42:601-609
We designed, optimized, and extensively tested several sensitive and specific real-time PCR assays for rapid detection of both smallpox and pan -orthopox virus DNAs. The assays are based on TaqMan 3′-minor groove binder chemistry and were performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a023a5a6cb736b94552d05c1a5eeb7
https://doi.org/10.1128/jcm.42.2.601-609.2004
https://doi.org/10.1128/jcm.42.2.601-609.2004
Publikováno v:
Journal of Biological Chemistry. 275:30050-30057
A human cellular factor (OF-1) has been previously implicated in replication of herpes simplex virus, type 1. This protein binds to three conserved regions (Boxes I, II, and III) in the viral replication origin and appears to be required for viral DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::792f08d4394385f09cba925774aac00e
https://doi.org/10.1074/jbc.m002154200
https://doi.org/10.1074/jbc.m002154200
Autor:
Robert O. Baker
This chapter hopes to take a few modest steps towards articulating how reading the Bible affects readers in their entire person. It attempts to outline an approach to doing an affective reading in the New Testament. The reader-response theory of Wolf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::763aadf9e963013c3c9144a0e42a875f
https://doi.org/10.1163/9789004258259_008
https://doi.org/10.1163/9789004258259_008
Autor:
Robert O. Baker
Publikováno v:
Journal of Pentecostal Theology. 3:34-48
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da0e3a7b5ae4b426fedd24a5b3809c89
https://doi.org/10.1177/096673699500300704
https://doi.org/10.1177/096673699500300704
Autor:
Thomas R. Bailey, Kathy A. Keith, Daniel C. Pevear, John W. Huggins, Robert O. Baker, Guang Yang, Christopher J. Burns, Marc S. Collett, Sanjeev Tohan, Gerry Rhodes, Dennis Hruby, Earl R. Kern, Elizabeth Opsitnick, Dongcheng Dai, Susan R. Rippin, Robert Jordan
Publikováno v:
Journal of medicinal chemistry. 50(7)
A series of novel, potent orthopoxvirus egress inhibitors was identified during high-throughput screening of the ViroPharma small molecule collection. Using structure--activity relationship information inferred from early hits, several compounds were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70758564356fcdfbecbf414cdd075894
https://pubmed.ncbi.nlm.nih.gov/17335190
https://pubmed.ncbi.nlm.nih.gov/17335190
Publikováno v:
Antiviral research. 55(1)
3-Deazaneplanocin A, an analog of adenosine, is a potent inhibitor of Ebola virus replication. A single dose early in infection prevents illness and death in Ebola virus-infected mice. The ability of this and similar compounds to block both RNA and D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f11c128c2dea2dd2a02152bb5054008
https://pubmed.ncbi.nlm.nih.gov/12076759
https://pubmed.ncbi.nlm.nih.gov/12076759
Autor:
Jennifer D. Hall, Robert O. Baker
Publikováno v:
The Journal of biological chemistry. 273(37)
The D368A mutation within the 3′-5′-exonuclease domain of the herpes simplex type 1 DNA polymerase inactivates this nuclease and severely interferes with virus viability. Compared with the wild type enzyme, the D368A mutant exhibits substantially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6395fc3047422cf71893607b4d3e6965
https://pubmed.ncbi.nlm.nih.gov/9727026
https://pubmed.ncbi.nlm.nih.gov/9727026