Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Robert Nisticò"'
Autor:
Gaia Piccioni, Nunzia Maisto, Asia d’Ettorre, Georgios Strimpakos, Robert Nisticò, Viviana Triaca, Dalila Mango
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Microglia, traditionally regarded as innate immune cells in the brain, drive neuroinflammation and synaptic dysfunctions in the early phases of Alzheimer disease (AD), acting upstream to Aβ accumulation. Colony stimulating factor 1-receptor
Externí odkaz:
https://doaj.org/article/b97ed4eb6cf64d939034c04ea89fbcbf
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 12, Pp 2583-2585 (2024)
Externí odkaz:
https://doaj.org/article/9ed0546adbeb45abb62504b14e549ff8
Autor:
Laura Rinaldi, Rossella Delle Donne, Bruno Catalanotti, Omar Torres-Quesada, Florian Enzler, Federica Moraca, Robert Nisticò, Francesco Chiuso, Sonia Piccinin, Verena Bachmann, Herbert H. Lindner, Corrado Garbi, Antonella Scorziello, Nicola Antonino Russo, Matthis Synofzik, Ulrich Stelzl, Lucio Annunziato, Eduard Stefan, Antonio Feliciello
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/b60ef57fb3a54223b0e982ee57f2c310
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/637bfe7d41c444b9b912641c2fd37ede
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Novel effective therapeutic strategies are needed to treat brain neurodegenerative diseases and to improve the quality of life of patients affected by Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), Amyotrophic La
Externí odkaz:
https://doaj.org/article/24b8600285e949e5b21d47c5e7474e4c
Autor:
Dalila Mango, Robert Nisticò
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 2, Pp 324-324 (2023)
Externí odkaz:
https://doaj.org/article/003e1ff12ab1480fac3bd8a643f57688
Autor:
Dalila Mango, Robert Nisticò
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Acidic pH shift occurs in many physiological neuronal activities such as synaptic transmission and synaptic plasticity but also represents a characteristic feature of many pathological conditions including inflammation and ischemia. Neuroinflammation
Externí odkaz:
https://doaj.org/article/55e6824df7e44236b886f0dab668df7a
Autor:
Laura Rinaldi, Rossella Delle Donne, Bruno Catalanotti, Omar Torres-Quesada, Florian Enzler, Federica Moraca, Robert Nisticò, Francesco Chiuso, Sonia Piccinin, Verena Bachmann, Herbert H Lindner, Corrado Garbi, Antonella Scorziello, Nicola Antonino Russo, Matthis Synofzik, Ulrich Stelzl, Lucio Annunziato, Eduard Stefan, Antonio Feliciello
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Abstract Activation of G-protein coupled receptors elevates cAMP levels promoting dissociation of protein kinase A (PKA) holoenzymes and release of catalytic subunits (PKAc). This results in PKAc-mediated phosphorylation of compartmentalized substrat
Externí odkaz:
https://doaj.org/article/365bbfa6102046adbb84b30bd59fe56c
Autor:
Harald Hampel, Filippo Caraci, A. Claudio Cuello, Giuseppe Caruso, Robert Nisticò, Massimo Corbo, Filippo Baldacci, Nicola Toschi, Francesco Garaci, Patrizia A. Chiesa, Steven R. Verdooner, Leyla Akman-Anderson, Félix Hernández, Jesús Ávila, Enzo Emanuele, Pedro L. Valenzuela, Alejandro Lucía, Mark Watling, Bruno P. Imbimbo, Andrea Vergallo, Simone Lista
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Neuroinflammation commences decades before Alzheimer's disease (AD) clinical onset and represents one of the earliest pathomechanistic alterations throughout the AD continuum. Large-scale genome-wide association studies point out several genetic vari
Externí odkaz:
https://doaj.org/article/d53ee7186b6d45b1a92b5fefb91691d8
Autor:
Marzia Soligo, Sonia Piccinin, Virginia Protto, Francesca Gelfo, Maria Egle De Stefano, Fulvio Florenzano, Erica Berretta, Laura Petrosini, Robert Nisticò, Luigi Manni
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract The muscarinic receptor response to acetylcholine regulates the hippocampal-related learning, memory, neural plasticity and the production and processing of the pro-nerve growth factor (proNGF) by hippocampal cells. The development and progr
Externí odkaz:
https://doaj.org/article/b7ac817b23ce4e5da5be57d43e6f9e1b