Zobrazeno 1 - 10 of 116 pro vyhledávání: '"Robert N. Hughes"'
1
Sex still matters: has the prevalence of male-only studies of drug effects on rodent behaviour changed during the past decade?
Autor: Robert N. Hughes
Publikováno v: Behavioural Pharmacology. 30:95-99
During the past 10 years, for a number of biomedical disciplines, including behavioural pharmacology, there have been appeals to include both sexes in animal studies of processes that are not sex specific. In 2007, a survey of experimental studies of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fcddc882de8cbe98491a692d122a086
https://doi.org/10.1097/fbp.0000000000000410
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2
Effects of olanzapine on anxiety-related behaviour in male and female rats assessed after 21-24 and 42-45 days of chronic treatment
Autor: Robert N. Hughes, Molly R Lockington
Publikováno v: Behavioural pharmacology. 32(3)
Olanzapine can decrease anxiety and impair memory, but there is limited information about length of treatment or sex differences in its effectiveness. Therefore, effects of 21-24 and 41-45 days of treatment and sex differences on anxiety-related beha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e7f6cbf866c7ba430b4ade5e38bb26
https://pubmed.ncbi.nlm.nih.gov/33229894
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3
Increased anxiety and impaired spatial memory in young adult rats following adolescent exposure to methylone
Autor: Jollee J. Daniel, Robert N. Hughes
Publikováno v: Pharmacology Biochemistry and Behavior. :44-49
This study investigated the possibility that treatment of adolescent rats with the substituted cathinone, 3,4-methylenedioxymethcathinone (methylone), might result in heightened anxiety and/or impaired memory during early adulthood, as has been shown
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ad9b883bee79104358c4163c27bec1
https://doi.org/10.1016/j.pbb.2016.05.003
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5
Strain-dependent effects of acute caffeine on anxiety-related behavior in PVG/c, Long–Evans and Wistar rats
Autor: Nicola J. Hancock, Robert N. Hughes
Publikováno v: Pharmacology Biochemistry and Behavior. 140:51-61
To assess the possibility that acute caffeine's behavioral action might depend on rats' strain, effects of 50mg/kg of the drug were observed on activity, anxiety-related behavior and habituation learning in male and female rats from three different s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8aa35c75713dab1bac29939c29d5e3c
https://doi.org/10.1016/j.pbb.2015.11.005
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6
Treatment with 1-benzylpiperazine (BZP) during adolescence of male and female hooded rats exposed to environmental enrichment: Subsequent behavioral outcomes
Autor: Robert N. Hughes, Ellen I. Dixon
Publikováno v: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 73
From 30 days after birth until the completion of the study, male and female rats were caged in same-sexed twos or threes either with (enriched cages, EC) or without several objects for them to explore (standard cages, SC). From 41 to 50 days of age (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca6a921773ca98a8a82a57ed254d3bea
https://pubmed.ncbi.nlm.nih.gov/30590115
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8
Drug-, dose- and sex-dependent effects of chronic fluoxetine, reboxetine and venlafaxine on open-field behavior and spatial memory in rats
Autor: Vanessa C. Gray, Robert N. Hughes
Publikováno v: Behavioural Brain Research. 281:43-54
In an effort to address the need to include both sexes in studies of effects of the SSRI fluoxetine, the NRI reboxetine and the SNRI venlafaxine on anxiety-related behavior and memory along with the use of chronic drug administration, male and female
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b7d61a913c6457ab6c0cc262ddeb41
https://doi.org/10.1016/j.bbr.2014.12.023
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9
Sex-dependent modification by chronic caffeine of acute methamphetamine effects on anxiety-related behavior in rats
Autor: Jennifer J. Hamilton, Robert N. Hughes
Publikováno v: Behavioural brain research. 345
For fourteen days, male and female PVG/c hooded rats were provided continuously with either pure drinking water, or water containing caffeine in a quantity approximating a daily dose of 31.1 mg/kg. Then at intervals of 3 days, they were administered
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224c71b251136ccb4432325db953c201
https://pubmed.ncbi.nlm.nih.gov/29476897
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10
Increased anxiety-related behavior in male and female adult rats following early and late adolescent exposure to 3,4-methylenedioxymethamphetamine (MDMA)
Autor: Olga V. Kolyaduke, Robert N. Hughes
Publikováno v: Pharmacology Biochemistry and Behavior. 103:742-749
Subsequent behavioral effects in adulthood of daily exposure to MDMA during early or late adolescence were assessed in both male and female rats. From either postnatal day (PND) 35 (early adolescence) or PND45 (late adolescence), PVG/c rats of each s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d8503ab80e04bd63c6689ad41ef729
https://doi.org/10.1016/j.pbb.2012.12.004
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