Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Robert N. Cooney"'
Autor:
Tackla Winston, Yuanhui Song, Huaiyu Shi, Junhui Yang, Munther Alsudais, Maria I. Kontaridis, Yaoying Wu, Thomas R. Gaborski, Qinghe Meng, Robert N. Cooney, Zhen Ma
Publikováno v:
Advanced Science, Vol 11, Iss 28, Pp n/a-n/a (2024)
Abstract Over the past decades, mesenchymal stromal cells (MSCs) have been extensively investigated as a potential therapeutic cell source for the treatment of various disorders. Differentiation of MSCs from human induced pluripotent stem cells (iMSC
Externí odkaz:
https://doaj.org/article/c3c1a98291a240ac8fb96bf60b6ff868
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Galantamine, a centrally acting acetylcholinesterase inhibitor, has been shown to attenuate inflammation and insulin resistance in patients with metabolic syndrome. We investigated the effects of galantamine on glycemic control and developme
Externí odkaz:
https://doaj.org/article/6ef35a75ddeb4ddc84095c86550f5495
Autor:
Qinghe Meng, Xinghan Tian, Junwei Li, Napat Pruekprasert, Ravi Dhawan, George G. Holz, Robert N. Cooney
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Diabetic nephropathy (DN) is a serious complicating factor in human type 2 diabetes mellitus (T2DM), and it commonly results in end-stage renal disease (ESRD) that requires kidney dialysis. Here, we report that the α7 nicotinic acetylcholin
Externí odkaz:
https://doaj.org/article/987c01b7582a4d63a37cce4c2b02a8fd
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
IntroductionThe gastrointestinal tract plays a major role in regulating glucose homeostasis and gut endocrine function. The current study examines the effects of Roux-en-Y gastric bypass (RYGB) on intestinal GLP-1, glucose transporter expression and
Externí odkaz:
https://doaj.org/article/6133ba176a1842879aad745eb9f9f0e7
Autor:
Alex Helkin, Sumeet V. Jain, Angelika Gruessner, Maureen Fleming, Leslie Kohman, Michael Costanza, Robert N. Cooney
Publikováno v:
Perioperative Medicine, Vol 6, Iss 1, Pp 1-6 (2017)
Abstract Background The ASA physical classification score has a major impact on the observed/expected (O/E) mortality ratio in the NSQIP General Vascular Mortality Model. The difference in predicted mortality is greatest between ASAs 3 and 4. We hypo
Externí odkaz:
https://doaj.org/article/8035155363584614a5510f2dbb8dc52d
Publikováno v:
Journal of Obesity, Vol 2011 (2011)
Externí odkaz:
https://doaj.org/article/47d00a0be0a546588e5aeb13b6a91731
Autor:
Julia Ma, Xiaojing Wang, Raymond Gu, Dandan Guo, Changying Shi, Michaela Kollisch-Singule, Liye Suo, Juntao Luo, Qinghe Meng, Robert N. Cooney
Publikováno v:
Shock. 59:922-929
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aed21e95d6b769f0fcd83cd3ce2d33af
https://doi.org/10.1097/shk.0000000000002118
https://doi.org/10.1097/shk.0000000000002118
Autor:
Qinghe Meng, Oleg G. Chepurny, Colin A. Leech, Napat Pruekprasert, Megan E. Molnar, James Jason Collier, Robert N. Cooney, George G. Holz
Publikováno v:
Diabetes Obes Metab
AIM: α7nAChR agonist GTS-21 is potentially a new treatment for type 2 diabetes (T2D) owing to its ability to stimulate GLP-1 secretion. This study sought to establish if GTS-21 exerts a blood glucose-lowering action in db/db mice, and to test if thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::688e59c554c6461193dab83539cbaefa
https://doi.org/10.1111/dom.14693
https://doi.org/10.1111/dom.14693
Publikováno v:
Shock. 56:1057-1065
During sepsis the normal induction of circulating insulin-like growth factor-I (IGF-I) by growth hormone (GH) action on liver is attenuated, a phenomenon called hepatic GH resistance. Hepatic GH resistance can be caused by cytokine-mediated activatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b7c43d219a701640838756e71456f97
https://doi.org/10.1097/shk.0000000000001792
https://doi.org/10.1097/shk.0000000000001792
Autor:
Qinghe Meng, Xiaojing Wang, Dandan Guo, Changying Shi, Raymond Gu, Julia Ma, Gary Nieman, Michaela Kollisch-Singule, Juntao Luo, Robert N. Cooney
Publikováno v:
Shock (Augusta, Ga.). 57(5)
Intratracheal (IT) lipopolysaccharide (LPS) causes severe acute lung injury (ALI) and systemic inflammation. CMT-3 has pleiotropic anti-inflammatory effects including matrix metalloproteinase (MMP) inhibition, attenuation of neutrophil (PMN) activati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c482cac8d996de1063bf7679ab05bd4
https://pubmed.ncbi.nlm.nih.gov/35583915
https://pubmed.ncbi.nlm.nih.gov/35583915