Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Robert N Nishimura"'
Autor:
Fei Cao, Caroline Tang, Xiaoyong Chen, Zewei Tu, Ying Jin, Olivia M. Turk, Robert N. Nishimura, Allen Ebens, Valentina Dubljevic, James A. Campbell, Jiangbing Zhou, James E. Hansen
Publikováno v:
ACS Central Science, Vol 10, Iss 8, Pp 1562-1572 (2024)
Externí odkaz:
https://doaj.org/article/c37714a68d904a949ff847e1da1a6595
Autor:
Tariq Bashir, Cheri Cloninger, Nicholas Artinian, Lauren Anderson, Andrew Bernath, Brent Holmes, Angelica Benavides-Serrato, Nesrin Sabha, Robert N Nishimura, Abhijit Guha, Joseph Gera
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47741 (2012)
Hyperactivation of the mTORC2 signaling pathway has been shown to contribute to the oncogenic properties of gliomas. Moreover, overexpression of the mTORC2 regulatory subunit Rictor has been associated with increased proliferation and invasive charac
Externí odkaz:
https://doaj.org/article/721fd34cf976430c8349f3a93c63e338
Autor:
Brent Holmes, Angelica Benavides-Serrato, Jacquelyn T. Saunders, Sunil Kumar, Robert N. Nishimura, Joseph Gera
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 9, Pp 951-965 (2021)
The Hippo and mTOR signaling cascades are major regulators of cell growth and division. Aberrant regulation of these pathways has been demonstrated to contribute to gliomagenesis and result in enhanced glioblastoma proliferation and invasive characte
Externí odkaz:
https://doaj.org/article/b01e8986ccf741549a1fff9a968ce1fb
Autor:
Jacquelyn T. Saunders, Sunil Kumar, Angelica Benavides-Serrato, Brent Holmes, Kennedy E. Benavides, Muhammad T. Bashir, Robert N. Nishimura, Joseph Gera
Publikováno v:
Journal of Neuro-Oncology. 163:207-218
Introduction HGF/c-MET signaling is a significant driver of glioblastoma (GBM) growth and disease progression. Unfortunately, c-MET targeted therapies have been found to be largely ineffective suggesting additional redundant mechanisms of c-MET activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7af1f1b527e20811fcb6f4bcd6e455df
https://doi.org/10.1007/s11060-023-04331-5
https://doi.org/10.1007/s11060-023-04331-5
Autor:
Chris Hino, Grace Chan, Gwen Jordaan, Sophia S. Chang, Jacquelyn T. Saunders, Mohammad T. Bashir, James E. Hansen, Joseph Gera, Richard H. Weisbart, Robert N. Nishimura
Publikováno v:
Cell Stress and Chaperones.
Heat shock proteins (HSPs), especially Hsp70 (HSPA1), have been associated with cellular protection from various cellular stresses including heat, hypoxia-ischemia, neurodegeneration, toxins, and trauma. Endogenous HSPs are often synthesized in direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5088e42a4fd95c0d30dfd168cdfab94
https://doi.org/10.1007/s12192-023-01349-6
https://doi.org/10.1007/s12192-023-01349-6
Autor:
Chris Hino, Grace Chan, Gwen Jordaan, Sophia S Chang, Jacquelyn T Saunders, Mohammad T Bashir, James E Hansen, Joseph Gera, Richard H Weisbart, Robert N Nishimura
Heat shock proteins (HSPs), especially Hsp70 (HSPA1), have been associated with cellular protection from various cellular stresses including heat, hypoxia-ischemia, neurodegeneration, toxins, and trauma. Endogenous HSPs are often synthesized in direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91a5f5c4abf1e10850f4f5e179a746a8
https://doi.org/10.1101/2023.02.22.529417
https://doi.org/10.1101/2023.02.22.529417
Autor:
Xiaoyong Chen, Xiangjun Tang, Benedette J. Cuffari, Caroline Tang, Xingchun Gao, Philip W. Noble, Melissa R. Young, Olivia M. Turk, Anupama Shirali, Joseph Gera, Robert N. Nishimura, Jiangbing Zhou, James E. Hansen
Cytoplasmic DNA triggers a cGAS-mediated signaling cascade that promotes an innate immune response and is potentially actionable in cancer immunotherapy. Here we show that a cytoplasmic-localizing lupus anti-DNA autoantibody activates cGAS and facili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::687060f5a805c416e3b8b25dbe9dcbe9
https://doi.org/10.1101/2023.02.11.527649
https://doi.org/10.1101/2023.02.11.527649
Autor:
Sunil Kumar, Robert N. Nishimura, Jacquelyn T Saunders, Angelica Benavides-Serrato, Brent Holmes, Joseph Gera
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 9, Pp 951-965 (2021)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
The Hippo and mTOR signaling cascades are major regulators of cell growth and division. Aberrant regulation of these pathways has been demonstrated to contribute to gliomagenesis and result in enhanced glioblastoma proliferation and invasive characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93125b3b9c909d064550cda15a19ad9f
https://doi.org/10.1016/j.neo.2021.07.005
https://doi.org/10.1016/j.neo.2021.07.005
Autor:
Angelica Benavides-Serrato, Jacquelyn T. Saunders, Sunil Kumar, Brent Holmes, Kennedy E. Benavides, Muhammad T. Bashir, Robert N. Nishimura, Joseph Gera
Publikováno v:
Cancer Letters. 562:216178
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db70e0ae294e800283f2b8fe19eb2237
https://doi.org/10.1016/j.canlet.2023.216178
https://doi.org/10.1016/j.canlet.2023.216178
Autor:
Sunil Kumar, Jacquelyn T Saunders, Angelica Benavides-Serrato, Brent Holmes, Joseph Gera, Robert N. Nishimura
Publikováno v:
J Neurooncol
INTRODUCTION: Recent studies have suggested that dysregulated Hippo pathway signaling may contribute to glioblastoma proliferation and invasive characteristics. The downstream effector of the pathway, the Yes-associated protein (YAP) oncoprotein, has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc6760bfbaf4c5571c9977c3531abf2
https://doi.org/10.1007/s11060-021-03699-6
https://doi.org/10.1007/s11060-021-03699-6