Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Robert Musiol"'
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Among tyrosine kinase inhibitors, quinazoline-based compounds represent a large and well-known group of multi-target agents. Our previous studies have shown interesting kinases inhibition activity for a series of 4-aminostyrylquinazolines based on th
Externí odkaz:
https://doaj.org/article/41592074e8584c39986e5b1bb5927624
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Abstract A novel pro-dye approach for the acid-selective staining of the subcellular compartments for better permeability and selectivity was applied. The designed sensor has suitable physicochemical properties such as a large Stokes shift and a long
Externí odkaz:
https://doaj.org/article/8c5916d708804c0bbfd70347e85d60a5
Autor:
Barbara Czaplińska, Katarzyna Malarz, Anna Mrozek-Wilczkiewicz, Aneta Slodek, Mateusz Korzec, Robert Musiol
Publikováno v:
Molecules, Vol 25, Iss 11, p 2488 (2020)
A series of novel styrylquinolines with the benzylidene imine moiety were synthesized and spectroscopically characterized for their applicability in cellular staining. The spectroscopic study revealed absorption in the ultraviolet–visible region (3
Externí odkaz:
https://doaj.org/article/53eb89672b6d4fe2b8fd15d19a4bc462
Publikováno v:
Molecules, Vol 25, Iss 2, p 345 (2020)
Styrylquinolines are heterocyclic compounds that are known for their antifungal and antimicrobial activity. Metal complexation through hydroxyl groups has been claimed to be a plausible mechanism of action for these types of compounds. A series of no
Externí odkaz:
https://doaj.org/article/ae3daeb4c9f1402fb057cda48413512e
Autor:
Marta Rejmund, Anna Mrozek-Wilczkiewicz, Katarzyna Malarz, Monika Pyrkosz-Bulska, Kamila Gajcy, Mieczyslaw Sajewicz, Robert Musiol, Jaroslaw Polanski
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0188767 (2018)
A new class of TSCs containing piperazine (piperazinylogs) of Triapine, was designed to fulfill the di-substitution pattern at the TSCs N4 position, which is a crucial prerequisite for the high activity of the previously obtained TSC compounds-DpC an
Externí odkaz:
https://doaj.org/article/ac0a013dbe3f40279c1064ea5199134e
Autor:
Jaroslaw Polanski, Marcela Vejsova, Alicja Ratuszna, Robert Musiol, Katarina Kralova, Matus Pesko, Josef Jampilek, Anna Mrozek-Wilczkiewicz, Maciej Serda
Publikováno v:
Molecules, Vol 17, Iss 11, Pp 13483-13502 (2012)
Two series of thiosemicarbazone-based iron chelators (twenty-seven compounds) were designed and synthesized using a microwave-assisted approach. Quinoline and halogenated phenyl were selected as parent scaffolds on the basis of a similarity search. T
Externí odkaz:
https://doaj.org/article/debc45c39c104f23a3ee1bc74ebddf3a
Autor:
Aidan Coffey, Jim O'Mahony, Marcela Vejsova, Katarina Kralova, James Carroll, Jacek E. Nycz, Matus Pesko, Josef Jampilek, Robert Musiol, Anna Mrozek, Jaroslaw Polanski
Publikováno v:
Molecules, Vol 15, Iss 1, Pp 288-304 (2010)
In this study, a series of fourteen ring-substituted 8-hydroxyquinoline derivatives were prepared. The synthesis procedures are presented. The compounds were analyzed using RP-HPLC to determine lipophilicity. They were tested for their activity relat
Externí odkaz:
https://doaj.org/article/6552a88029994d4281bcafbb6c06677d
Autor:
Jaroslaw Polanski, Jiri Dohnal, Jim O'Mahony, Aidan Coffey, Marcela Vejsova, James Carroll, Katarina Kralova, Matus Pesko, Robert Musiol, Jacek Finster, Josef Jampilek
Publikováno v:
Molecules, Vol 14, Iss 10, Pp 4246-4265 (2009)
In this study, series of ring-substituted 2-styrylquinazolin-4(3H)-one and 4-chloro-2-styrylquinazoline derivatives were prepared. The syntheses of the discussed compounds are presented. The compounds were analyzed by RP-HPLC to determine lipophilici
Externí odkaz:
https://doaj.org/article/8b9a65a6f3614b7fa5de80c0834f6aa5
Autor:
Jiri Dohnal, Jozef Csollei, Jaroslaw Polanski, Dominik Tabak, Halina Niedbala, Violetta Kozik, James Carroll, Jacek Finster, Aidan Coffey, Matus Pesko, Josef Jampilek, Marcela Vejsova, Katarina Kralova, Robert Musiol
Publikováno v:
Molecules, Vol 14, Iss 3, Pp 1145-1159 (2009)
In the study, a series of twelve ring-substituted 4-hydroxy-1H-quinolin-2-one derivatives were prepared. The procedures for synthesis of the compounds are presented. The compounds were analyzed using RP-HPLC to determine lipophilicity and tested for
Externí odkaz:
https://doaj.org/article/79183ca347834afebbcd30818c3cb7fd
Autor:
Marzena Rams-Baron, Mateusz Dulski, Anna Mrozek-Wilczkiewicz, Mateusz Korzec, Wioleta Cieslik, Ewelina Spaczyńska, Piotr Bartczak, Alicja Ratuszna, Jaroslaw Polanski, Robert Musiol
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131210 (2015)
New styrylquinoline derivatives with their photophysical constants are described. The synthesis was achieved via Sonogashira coupling using the newly developed heterogeneous nano-Pd/Cu catalyst system, which provides an efficient synthesis of high pu
Externí odkaz:
https://doaj.org/article/d123d87bdc05428288aa3b2c71725a1a