Zobrazeno 1 - 10
of 1 418
pro vyhledávání: '"Robert Murray"'
Autor:
John Marsden, Mike Kelleher, Eilish Gilvarry, Luke Mitcheson, Jatinder Bisla, Angela Cape, Fiona Cowden, Edward Day, Jonathan Dewhurst, Rachel Evans, Will Hardy, Andrea Hearn, Joanna Kelly, Natalie Lowry, Martin McCusker, Caroline Murphy, Robert Murray, Tracey Myton, Sophie Quarshie, Rob Vanderwaal, April Wareham, Dyfrig Hughes, Zoë Hoare
Publikováno v:
EClinicalMedicine, Vol 66, Iss , Pp 102311- (2023)
Summary: Background: Daily methadone maintenance or buprenorphine treatment is the standard-of-care (SoC) medication for opioid use disorder (OUD). Subcutaneously injected, extended-release buprenorphine (BUP-XR) may be more effective—but there has
Externí odkaz:
https://doaj.org/article/74984ad835324f68b7da701787e3a009
Autor:
John Marsden, Mike Kelleher, Zoë Hoare, Dyfrig Hughes, Jatinder Bisla, Angela Cape, Fiona Cowden, Edward Day, Jonathan Dewhurst, Rachel Evans, Andrea Hearn, Joanna Kelly, Natalie Lowry, Martin McCusker, Caroline Murphy, Robert Murray, Tracey Myton, Sophie Quarshie, Gemma Scott, Sophie Turner, Rob Vanderwaal, April Wareham, Eilish Gilvarry, Luke Mitcheson
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-19 (2022)
Abstract Background Sublingual tablet buprenorphine (BUP-SL) and oral liquid methadone (MET) are the daily, standard-of-care (SOC) opioid agonist treatment medications for opioid use disorder (OUD). A sizable proportion of the OUD treatment populatio
Externí odkaz:
https://doaj.org/article/c1de5f4dc8184921b4e125d09f8a1f10
Autor:
Philip Titcombe, Robert Murray, Matthew Hewitt, Elie Antoun, Cyrus Cooper, Hazel M Inskip, Joanna D Holbrook, Keith M Godfrey, Karen Lillycrop, Mark Hanson, Sheila J Barton
Publikováno v:
Epigenetics, Vol 17, Iss 6, Pp 653-664 (2022)
DNA methylation (DNAm) in mammals is mostly examined within the context of CpG dinucleotides. Non-CpG DNAm is also widespread across the human genome, but the functional relevance, tissue-specific disposition, and inter-individual variability has not
Externí odkaz:
https://doaj.org/article/08c0ed1ceebd437e87b7e6a94af68e3e
Publikováno v:
Frontiers in Nutrition, Vol 9 (2023)
Ensuring healthy lives and promoting wellbeing across the age spectrum are essential to sustainable development. Nutrition is at the heart of the World Health Organization (WHO) Sustainable Development Goals, particularly for Sustainable Development
Externí odkaz:
https://doaj.org/article/5acb8893a19d46be87ec06a333ac1450
Autor:
Sherald Sanchez, Farah Jindani, Jing Shi, Mark van der Maas, Sylvia Hagopian, Robert Murray, Nigel Turner
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Although Internet-based interventions (IBIs) have been around for two decades, uptake has been slow. Increasing the acceptability of IBIs among end users may increase uptake. In this study, we explored the factors that shape accep
Externí odkaz:
https://doaj.org/article/cc199a44b275433fbcfa6dec0ef235ef
Autor:
Seung-hee Lee, Robert Murray Field
Publikováno v:
Nuclear Engineering and Technology, Vol 51, Iss 2, Pp 618-625 (2019)
When newcomer countries consider a nuclear power programme, it is recognized that the most important organizations are the Nuclear Energy Programme Implementing Organization (NEPIO), the regulator, and an operating organization. Concerning the number
Externí odkaz:
https://doaj.org/article/8853ce84b96d4d2d822d41e60f6606be
Autor:
Elie Antoun, Negusse T Kitaba, Philip Titcombe, Kathryn V Dalrymple, Emma S Garratt, Sheila J Barton, Robert Murray, Paul T Seed, Joanna D Holbrook, Michael S Kobor, David Ts Lin, Julia L MacIsaac, Graham C Burdge, Sara L White, Lucilla Poston, Keith M Godfrey, Karen A Lillycrop, UPBEAT Consortium
Publikováno v:
PLoS Medicine, Vol 17, Iss 11, p e1003229 (2020)
BackgroundHigher maternal plasma glucose (PG) concentrations, even below gestational diabetes mellitus (GDM) thresholds, are associated with adverse offspring outcomes, with DNA methylation proposed as a mediating mechanism. Here, we examined the rel
Externí odkaz:
https://doaj.org/article/b2fe24c15dd443af8b059bf9123fd7ff
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 6 (2019)
Externí odkaz:
https://doaj.org/article/41a220aac13e47d890e6d969aece9d85
Autor:
Karen Lillycrop, Robert Murray, Clara Cheong, Ai Ling Teh, Rebecca Clarke-Harris, Sheila Barton, Paula Costello, Emma Garratt, Eloise Cook, Philip Titcombe, Bhuvaneshwari Shunmuganathan, Samantha J. Liew, Yong-Cai Chua, Xinyi Lin, Yonghui Wu, Graham C. Burdge, Cyrus Cooper, Hazel M. Inskip, Neerja Karnani, James C. Hopkins, Caroline E. Childs, Carolina Paras Chavez, Philip C. Calder, Fabian Yap, Yung Seng Lee, Yap Seng Chong, Philip E. Melton, Lawrie Beilin, Rae-Chi Huang, Peter D. Gluckman, Nick Harvey, Mark A. Hanson, Joanna D. Holbrook, Keith M. Godfrey
Publikováno v:
EBioMedicine, Vol 19, Iss C, Pp 60-72 (2017)
Experimental studies show a substantial contribution of early life environment to obesity risk through epigenetic processes. We examined inter-individual DNA methylation differences in human birth tissues associated with child's adiposity. We identif
Externí odkaz:
https://doaj.org/article/b50df7b8db9e47929bab8c7d7eb822c2
Autor:
Sheila J. Barton, Phillip E. Melton, Philip Titcombe, Robert Murray, Sebastian Rauschert, Karen A. Lillycrop, Rae-Chi Huang, Joanna D. Holbrook, Keith M. Godfrey
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Background: Association studies of epigenome-wide DNA methylation and disease can inform biological mechanisms. DNA methylation is often measured in peripheral blood, with heterogeneous cell types with different methylation profiles. Influences such
Externí odkaz:
https://doaj.org/article/2d06ad43744e41b5964d2905ccc7a8e1