Zobrazeno 1 - 10
of 1 211
pro vyhledávání: '"Robert Morris"'
Autor:
Yuanli Zhen, Kai Liu, Lei Shi, Simran Shah, Qin Xu, Haley Ellis, Eranga R. Balasooriya, Johannes Kreuzer, Robert Morris, Albert S. Baldwin, Dejan Juric, Wilhelm Haas, Nabeel Bardeesy
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Genomic alterations that activate Fibroblast Growth Factor Receptor 2 (FGFR2) are common in intrahepatic cholangiocarcinoma (ICC) and confer sensitivity to FGFR inhibition. However, the depth and duration of response is often limited. Here,
Externí odkaz:
https://doaj.org/article/5cd054ddc21245bf928ef895954d9dac
Autor:
Jennifer Stalas, Robert Morris, Kun Bu, Kevin von Bargen, Rebekah Largmann, Kathryn Sanford, Jacob Vandeventer, Weiru Han, Feng Cheng
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e26462- (2024)
Background: Deep vein thrombosis (DVT) has been reported as an adverse event for patients receiving combined oral contraceptives. Norethindrone/ethinyl estradiol (NET/EE) and drospirenone/ethinyl estradiol (DRSP/EE) are two commonly prescribed combin
Externí odkaz:
https://doaj.org/article/e1adfc9f2bab4dfb90cd034ba66e4dbd
Autor:
Markus W. Schweiger, Zohreh Amoozgar, Pierre Repiton, Robert Morris, Semer Maksoud, Michael Hla, Eric Zaniewski, David P. Noske, Wilhelm Haas, Koen Breyne, Bakhos A. Tannous
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108807- (2024)
Summary: Glioblastoma (GBM) is the most aggressive brain tumor, presenting major challenges due to limited treatment options. Standard care includes radiation therapy (RT) to curb tumor growth and alleviate symptoms, but its impact on GBM is limited.
Externí odkaz:
https://doaj.org/article/db23f5ee32a4459ab10e27118100af65
Autor:
Nicholas Adzibolosu, Ayesha B. Alvero, Rouba Ali-Fehmi, Radhika Gogoi, Logan Corey, Roslyn Tedja, Hussein Chehade, Vir Gogoi, Robert Morris, Matthew Anderson, Julie Vitko, Clarissa Lam, Douglas B. Craig, Sorin Draghici, Thomas Rutherford, Gil Mor
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionOvarian cancer recurs in most High Grade Serous Ovarian Cancer (HGSOC) patients, including initial responders, after standard of care. To improve patient survival, we need to identify and understand the factors contributing to early or la
Externí odkaz:
https://doaj.org/article/262a995315a3479982fcdcf6edad0ecd
Autor:
Ye Sheng Phang, Creighton Heaukulani, Wijaya Martanto, Robert Morris, Mian Mian Tong, Roger Ho
Publikováno v:
JMIR Human Factors, Vol 10, p e42167 (2023)
BackgroundThe website mindline.sg is a stress management and coping website that can be accessed anonymously in Singapore for free. Although designed to serve individuals who are well or have mild depression and anxiety symptoms, mindline.sg may pote
Externí odkaz:
https://doaj.org/article/42b11d0b13ec4787b89c90d7575e4976
TGF-β in the microenvironment induces a physiologically occurring immune-suppressive senescent state
Autor:
Satoru Matsuda, Ajinkya Revandkar, Taronish D. Dubash, Arvind Ravi, Ben S. Wittner, Maoxuan Lin, Robert Morris, Risa Burr, Hongshan Guo, Karsen Seeger, Annamaria Szabolcs, Dante Che, Linda Nieman, Gad A. Getz, David T. Ting, Michael S. Lawrence, Justin Gainor, Daniel A. Haber, Shyamala Maheswaran
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112129- (2023)
Summary: TGF-β induces senescence in embryonic tissues. Whether TGF-β in the hypoxic tumor microenvironment (TME) induces senescence in cancer and how the ensuing senescence-associated secretory phenotype (SASP) remodels the cellular TME to influen
Externí odkaz:
https://doaj.org/article/d7cf1d03230041eaa0fc9ddd6ef3a6cf
Autor:
Radhika P. Gogoi, Sandra Galoforo, Alexandra Fox, Colton Morris, Harry Ramos, Vir K. Gogoi, Hussein Chehade, Nicholas K. Adzibolosu, Chenjun Shi, Jitao Zhang, Roslyn Tedja, Robert Morris, Ayesha B. Alvero, Gil Mor
Publikováno v:
Cancers, Vol 15, Iss 19, p 4834 (2023)
Background: Epithelial–mesenchymal transition (EMT) is a biological process where epithelial cells lose their adhesive properties and gain invasive, metastatic, and mesenchymal properties. Maintaining the balance between the epithelial and mesenchy
Externí odkaz:
https://doaj.org/article/6d508c9d3bc642a38e5eb8994e1ad9db
Autor:
Swetha Rajasekaran, Jalal Siddiqui, Jessica Rakijas, Brandon Nicolay, Chenyu Lin, Eshan Khan, Rahi Patel, Robert Morris, Emanuel Wyler, Myriam Boukhali, Jayashree Balasubramanyam, R. Ranjith Kumar, Capucine Van Rechem, Christine Vogel, Sailaja V. Elchuri, Markus Landthaler, Benedikt Obermayer, Wilhelm Haas, Nicholas Dyson, Wayne Miles
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Swetha Rajasekaran et al. integrate transcriptional, proteomic, and metabolomic data to explore how cells adapt to inactivation of RB1, a hallmark of cancer. Combined with their genetic analyses in a Drosophila model, the authors identify key metabol
Externí odkaz:
https://doaj.org/article/c522d3a225e8419ab1ce5e0411f3ed84
Autor:
Amit Roy, Randall J. Brenneman, Jacob Hogan, Justin M. Barnes, Yi Huang, Robert Morris, Sreekrishna Goddu, Michael Altman, Jose Garcia-Ramirez, Harold Li, Jacqueline E. Zoberi, Arnold Bullock, Eric Kim, Zachary Smith, Robert Figenshau, Gerald L. Andriole, Brian C. Baumann, Jeff M. Michalski, Hiram A. Gay
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 29, Iss , Pp 47-53 (2021)
Background: We present the first report comparing early toxicity outcomes with high-dose rate brachytherapy (HDR-BT) boost upfront versus intensity modulated RT (IMRT) upfront combined with androgen deprivation therapy (ADT) as definitive management
Externí odkaz:
https://doaj.org/article/7af1a850b3314a018b5f641b2fc46e0e
Autor:
Helen E. Groves, Jesse Papenburg, Kayur Mehta, Julie A. Bettinger, Manish Sadarangani, Scott A. Halperin, Shaun K. Morris, Christina Bancej, Catherine Burton, Joanne Embree, Cheryl Foo, Natalie Bridger, Robert Morris, Taj Jadavji, Marc Lebel, Nicole Le Saux, Karina A. Top, Ben Tan, Athena McConnell, Rupeena Purewal, Pierre Déry, Roseline Thibeault, Wendy Vaudry, Dat Tran, Laura Sauvé, Dorothy L. Moore, Marie-Astrid Lefebvre
Publikováno v:
The Lancet Regional Health. Americas, Vol 7, Iss , Pp 100132- (2022)
Summary: Background: The COVID-19 pandemic resulted in unprecedented implementation of wide-ranging public health measures globally. During the pandemic, dramatic decreases in seasonal influenza virus detection have been reported worldwide. Informati
Externí odkaz:
https://doaj.org/article/04356b7007db432ead2248a39ff6818c