Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Robert Morey"'
Autor:
Robert Morey, Tony Bui, Virginia Chu Cheung, Chen Dong, Joseph E. Zemke, Daniela Requena, Harneet Arora, Madeline G. Jackson, Donald Pizzo, Thorold W. Theunissen, Mariko Horii
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109569- (2024)
Summary: Preeclampsia (PE) is a hypertensive pregnancy disorder with increased risk of maternal and fetal morbidity and mortality. Abnormal extravillous trophoblast (EVT) development and function is considered to be the underlying cause of PE, but ha
Externí odkaz:
https://doaj.org/article/dd20a5899562403fa7defa0b04b10da9
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113710- (2024)
Summary: Without new transcription, gene expression across the oocyte-to-embryo transition (OET) relies instead on regulation of mRNA poly(A) tails to control translation. However, how tail dynamics shape translation across the OET in mammals remains
Externí odkaz:
https://doaj.org/article/ae91ef958e004aaeb729d2e7fdbc5c4d
Autor:
Jennifer N. Chousal, Robert Morey, Srimeenakshi Srinivasan, Katherine Lee, Wei Zhang, Ana Lisa Yeo, Cuong To, Kyucheol Cho, V. Gabriel Garzo, Mana M. Parast, Louise C. Laurent, Heidi Cook-Andersen
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113701- (2024)
Summary: Human embryo implantation is remarkably inefficient, and implantation failure remains among the greatest obstacles in treating infertility. Gene expression data from human embryos have accumulated rapidly in recent years; however, identifica
Externí odkaz:
https://doaj.org/article/13df70b330c94714a5a518c7f339944c
Autor:
Robert Morey, Omar Farah, Sampada Kallol, Daniela F. Requena, Morgan Meads, Matteo Moretto-Zita, Francesca Soncin, Louise C. Laurent, Mana M. Parast
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/787049014b1b49d99d6eb476d38b04ea
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105469- (2022)
Summary: A detailed understanding of the developmental substates of human pluripotent stem cells (hPSCs) is needed to optimize their use in cell therapy and for modeling early development. Genetic instability and risk of tumorigenicity of primed hPSC
Externí odkaz:
https://doaj.org/article/16400bccaf164f1f86b593afb9730059
Autor:
Mariko Horii, Robert Morey, Tony Bui, Ojeni Touma, Katharine K. Nelson, Hee-Young Cho, Hannah Rishik, Louise C. Laurent, Mana M. Parast
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Preeclampsia (PE) is a pregnancy-specific hypertensive disorder, affecting up to 10% of pregnancies worldwide. The primary etiology is considered to be abnormal development and function of placental cells called trophoblasts. We previously d
Externí odkaz:
https://doaj.org/article/5b11f81d8b0144a4b6f42f04eac8354b
Autor:
Robert Morey, Omar Farah, Sampada Kallol, Daniela F. Requena, Morgan Meads, Matteo Moretto-Zita, Francesca Soncin, Louise C. Laurent, Mana M. Parast
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
During pregnancy, conceptus-derived extravillous trophoblast (EVT) invades the endomyometrium, anchors the placenta to the maternal uterus, and remodels the spiral arteries in order to establish maternal blood supply to the fetoplacental unit. Recent
Externí odkaz:
https://doaj.org/article/63c82b3c6ccf4862baab8aa918ccffb2
Autor:
Ignacio Sancho-Martinez, Emmanuel Nivet, Yun Xia, Tomoaki Hishida, Aitor Aguirre, Alejandro Ocampo, Li Ma, Robert Morey, Marie N. Krause, Andreas Zembrzycki, Olaf Ansorge, Eric Vazquez-Ferrer, Ilir Dubova, Pradeep Reddy, David Lam, Yuriko Hishida, Min-Zu Wu, Concepcion Rodriguez Esteban, Dennis O’Leary, Geoffrey M. Wahl, Inder M. Verma, Louise C. Laurent, Juan Carlos Izpisua Belmonte
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Glioma can originate from the transformation of neural progenitor cells into glioma initiating cells. Here, the authors demonstrate the use of induced pluripotent stem cells as a suitable model for generating neural progenitor cells, which can be sub
Externí odkaz:
https://doaj.org/article/1fb354a0ffc8422d8d9d844eb2315537
Autor:
Rodolfo Gonzalez, Ibon Garitaonandia, Andrew Crain, Maxim Poustovoitov, Tatiana Abramihina, Alexander Noskov, Chuan Jiang, Robert Morey, Louise C. Laurent, John D. Elsworth, Evan Y. Snyder, D. Eugene Redmond, Ruslan Semechkin
Publikováno v:
Cell Transplantation, Vol 24 (2015)
Recent studies indicate that human pluripotent stem cell (PSC)-based therapies hold great promise in Parkinson's disease (PD). Clinical studies have shown that grafted fetal neural tissue can achieve considerable biochemical and clinical improvements
Externí odkaz:
https://doaj.org/article/cf4eef75b0934c0184aea0d846771d42
Autor:
Ibon Garitaonandia, Hadar Amir, Francesca Sesillo Boscolo, Gerald K Wambua, Heather L Schultheisz, Karen Sabatini, Robert Morey, Shannon Waltz, Yu-Chieh Wang, Ha Tran, Trevor R Leonardo, Kristopher Nazor, Ileana Slavin, Candace Lynch, Yingchun Li, Ronald Coleman, Irene Gallego Romero, Gulsah Altun, David Reynolds, Stephen Dalton, Mana Parast, Jeanne F Loring, Louise C Laurent
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118307 (2015)
The self-renewal and differentiation capacities of human pluripotent stem cells (hPSCs) make them a promising source of material for cell transplantation therapy, drug development, and studies of cellular differentiation and development. However, the
Externí odkaz:
https://doaj.org/article/7a2844f2408f4d81be97633913b4efe8