Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Robert Michael Saller"'
Autor:
Michael Schrewe, Matthias Löhr, Oliver V. Fabian, Robert Michael Saller, Eduard Ryschich, Walter Harms, Ralf Jesnowski, Jan Schmidt, Jörg Ringel, Alexander Engel
Publikováno v:
International Journal of Cancer. 113:649-653
Local therapy of pancreatic cancer with microencapsulated CYP2B1-producing cells and ifosfamide showed an effect both on the primary tumor and on distant metastatases. This possibly represents a consequence of the activation of immune response. Other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0147ed68a4c080a1b9ca67b8b31cc76a
https://doi.org/10.1002/ijc.20627
https://doi.org/10.1002/ijc.20627
Autor:
Zbigniew Gradski, Heinrich Prosl, Brian Salmons, Matthias Renner, Robert Michael Saller, Stanisław Winiarczyk, Cornelia Gabler, Barbara Kosztolich, Gerhardt König, Walter H. Günzburg, Johannes Hain
Publikováno v:
Journal of Molecular Medicine. 80:610-614
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de8378ccc32c777a2b598bf786555ca3
https://doi.org/10.1007/s00109-002-0356-0
https://doi.org/10.1007/s00109-002-0356-0
Autor:
Giovanni Esposito, Steffen Mitzner, Stefano Indraccolo, Alberto Amadori, Vincenzo Coppola, Robert Michael Saller, Walter H. Günzburg, Jan Stange, Brian Salmons
Publikováno v:
The Journal of Gene Medicine. 4:150-160
Background Because gene therapy of the future will primarily take an in vivo approach, a number of problems associated with its current implementation exist. Currently, repeated delivery of a vector in vivo is necessary to ensure adequate transfer of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93f34b7d1ea5a65f6ad5c02df93d4d36
https://doi.org/10.1002/jgm.257
https://doi.org/10.1002/jgm.257
Autor:
Thomas Kammertoens, Robert Michael Saller, Klemens Alton, Wolfgang Gelbmann, Brian Salmons, Wolfgang Uckert, Peter Karle, Walter H. Günzburg
Publikováno v:
Cancer Gene Therapy. 7:629-636
The success of chemotherapeutic intervention is limited because the necessary high local drug doses cannot be achieved without systemic toxicity. Application of suicide genes (SGs) and direct conversion of prodrugs (PDs) to toxic metabolites in situ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31ef4e97e349040f0799442bc6465f9
https://doi.org/10.1038/sj.cgt.7700139
https://doi.org/10.1038/sj.cgt.7700139
Autor:
Hartmut Stein, Peter Karle, Horst Nizze, Brian Salmons, Stefan Liebe, Thomas E. Wagner, Matthias Löhr, Walter H. Günzburg, Katrin Püschel, Petra Müller, Kerstin von Rombs, Regina Renz, Ralf Jesnowski, Robert Michael Saller
Publikováno v:
Karolinska Institutet
The prognosis of pancreatic cancer is poor, and current medical treatment is mostly ineffective. The aim of this study was to design a new treatment modality in an animal model system. We describe here a novel treatment strategy employing a mouse mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189ff24e4e248a223225774d253afe26
https://doi.org/10.1111/j.1749-6632.1999.tb09537.x
https://doi.org/10.1111/j.1749-6632.1999.tb09537.x
Autor:
Gerd Grasnick, Horst Dr Dautzenberg, Peter Karle, Matthias Löhr, Mireia Pelegrin, Kerstin von Rombs, Brian Salmons, Robert Michael Saller, Petra Müller, Walter H. Günzburg, Marc Piechaczyk, Ute Schuldt
Publikováno v:
Karolinska Institutet
Microencapsulation, as a tool for immunoisolation for allogenic or xenogenic implants, is a rapidly growing field. However most of the approaches are based on alginate/polylysine capsules, despite this system's obvious disadvantages such as its pyrog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ef198c682939f835698bd980ed8b95
https://doi.org/10.1111/j.1749-6632.1999.tb08493.x
https://doi.org/10.1111/j.1749-6632.1999.tb08493.x
Publikováno v:
Journal of Virology. 72:1699-1703
Mouse mammary tumor virus (MMTV)-based vectors are characterized by low titers. In an effort to transfer MMTV-specific regulation of gene expression to a more efficient murine leukemia virus (MLV) vector, we have replaced the complete 3′ U3 region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8161c613045850be0b8f06d210c493ea
https://doi.org/10.1128/jvi.72.2.1699-1703.1998
https://doi.org/10.1128/jvi.72.2.1699-1703.1998
Autor:
Michael Keese, R Prosst, Jörg W Sturm, S. Samel, M. Hafner, Robert Michael Saller, A Lux, Ralf Jesnowski, Stefan Post, Matthias Löhr
Publikováno v:
Cancer gene therapy. 13(1)
The prognosis of peritoneal spread from gastrointestinal cancer and subsequent malignant ascites is poor, and current medical treatments available are mostly ineffective. Targeted chemotherapy with intraperitoneal prodrug activation may be a benefici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e492ef439e3e1238f64f8ed64541af
https://pubmed.ncbi.nlm.nih.gov/16096652
https://pubmed.ncbi.nlm.nih.gov/16096652
Autor:
Johannes Hain, Matthias Löhr, Brian Salmons, Jörg Ringel, Grit Faulmann, Frank Hummel, Walter H. Günzburg, Robert Michael Saller
Publikováno v:
Cancer chemotherapy and pharmacology. 49
Background. Conventional chemotherapy of pancreatic carcinoma is only marginally effective. This is in part due to the severity of side effects following systemic administration of the cytostatic drug. The aim was to create a therapeutic tool allowin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b2578b547c06fc00cd18b57139f3098
https://pubmed.ncbi.nlm.nih.gov/12042985
https://pubmed.ncbi.nlm.nih.gov/12042985
Autor:
Reiko Wiessner, Karlheinz Hauenstein, Günter Klöppel, Kerstin von Rombs, Ilse Schwendenwein, Matthias Löhr, Robert Michael Saller, Helga Bergmeister, Peter Karle, Walter H. Günzburg, Robert Obermaier, Matthias Renner, A. Probst, Petra Müller, Udo Losert, Horst Nizze, Brian Salmons, Jens-Christian Kröger, Anne Hoffmeyer, Thomas E. Wagner, Zoltan Bago, Stefan Benz
Publikováno v:
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 3(1)
Background: The therapeutic efficacy of intratumoral instillation of genetically engineered, CYP2B1-expressing, microencapsulated cells in combination with ifosfamide had been previously demonstrated in xenografted human pancreatic ductal carcinomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43dfd4ca3efd4d43446c5dd7a80a2fbd
https://pubmed.ncbi.nlm.nih.gov/12649565
https://pubmed.ncbi.nlm.nih.gov/12649565