Výsledky vyhledávání - "Robert McNish"

Capacity for repeatable leukotriene generation after transient stimulation of mast cells and macrophages

Autor: G. Thomas Brock, W. Robert McNISH, Marc Peters-Golden

Publikováno v: Biochemical Journal. 329:519-525

Leukotriene (LT) synthesis is initiated by the enzyme 5-lipoxygenase (5-LO). Prolonged cell stimulation causes the translocation of 5-LO to the nuclear envelope and the synthesis of LT, with subsequent inactivation and persistent membrane association

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e922b334808eb19458ca2559b231038
https://doi.org/10.1042/bj3290519

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Biochemical basis for the low sensitivity of the rat heart to digitalis

Autor: James Chubb, Tai Akera, Satoshi Yamamoto, Theodore M. Brody, Robert McNish

Publikováno v: Naunyn-Schmiedeberg's Archives of Pharmacology. 308:81-88

The concentration of cardiac glycosides to produce positive inotropic effects in the rat heart is markedly higher than that in other species. Such a low digitalis sensitivity of the rat heat is attributed to the low affinity of cardiac Na+, K+-ATPase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204f4c4e96830012efd139f695a6ddd7
https://doi.org/10.1007/bf00499048

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Acute nephrotoxicities and hepatotoxicities of 1,2-dibromo-3-chloropropane and 1,2-dibromoethane in male and female F344 rats

Autor: Jerry B. Hook, Robert McNish, William M. Kluwe

Publikováno v: Toxicology Letters. 8:317-321

Four consecutive intraperitoneal (i.p.) injections with 40 mg/kg of 1,2-dibromo-3-chloropropane (DBCP) reduced the in vitro accumulation of p -aminohippurate (PAH) and tetraethylammonium (TEA) by slices of renal cortex and increased blood urea nitrog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aeb8c0dbd15c2729b95b7fb0038ed3c
https://doi.org/10.1016/0378-4274(81)90120-x

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Depletion by 1,2-dibromoethane, 1,2-dibromo-3-chloropropane, tris(2,3-dibromopropyl)phosphate,and hexachloro-1,3-butadiene of reduced non-protein sulfhydryl groups in target and non-target organs

Autor: Jerry B. Hook, William M. Kluwe, Kenneth G. Smithson, Robert McNish

Publikováno v: Biochemical Pharmacology. 30:2265-2271

the abilities of several aliphatic organohalide compounds to deplete reduced non-protein sulfhydryl (NPS)concentrations in rodent kidney, liver, lung, stomach, and testis were measured. the sites of NPS loss were compared to the sites of tissue injur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2580de838314265b5a9ca85458eabf00
https://doi.org/10.1016/0006-2952(81)90097-6

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