Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Robert McLeod"'
Autor:
Kushal Sejwal, Mohamed Chami, Hervé Rémigy, Renée Vancraenenbroeck, William Sibran, Rosmarie Sütterlin, Paul Baumgartner, Robert McLeod, Marie-Christine Chartier-Harlin, Veerle Baekelandt, Henning Stahlberg, Jean-Marc Taymans
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Leucine-rich repeat kinase 2 (LRRK2) is a large multidomain protein implicated in the pathogenesis of both familial and sporadic Parkinson’s disease (PD), and currently one of the most promising therapeutic targets for drug design in Parki
Externí odkaz:
https://doaj.org/article/b9e5473e709a4a3ca47905077e0c271d
Autor:
Dominic Jauvin, Jessina Chrétien, Sanjay K. Pandey, Laurie Martineau, Lucille Revillod, Guillaume Bassez, Aline Lachon, A. Robert McLeod, Geneviève Gourdon, Thurman M. Wheeler, Charles A. Thornton, C. Frank Bennett, Jack Puymirat
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 465-474 (2017)
Myotonic dystrophy type 1 (DM1), a dominant hereditary muscular dystrophy, is caused by an abnormal expansion of a (CTG)n trinucleotide repeat in the 3′ UTR of the human dystrophia myotonica protein kinase (DMPK) gene. As a consequence, mutant tran
Externí odkaz:
https://doaj.org/article/b019e0b86069472cbd72368b12dffd00
Autor:
Gregory Whiting, Eloise Bihar, Elliot Strand, Catherine Crichton, Megan Renny, Ignacy Bonter, Madhur Atreya, Adrian Gestos, Jim Haseloff, Tai Tran, Robert McLeod
In this work, we present a novel method for integrating printed electronic materials with biocompatible cryogels to form stable, implantable hydrogel-based bioelectronic devices that show stable long-term operation inside plant tissue. The gels can b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::011ffa6b5a8b7917d12911fe5a914df2
https://doi.org/10.21203/rs.3.rs-2753352/v1
https://doi.org/10.21203/rs.3.rs-2753352/v1
Autor:
Udai Banerji, Michelle D. Garrett, Florence I. Raynaud, Karen E. Swales, Sarah Mellor, Gavin Halbert, Stephanie Traub, Paul Jones, Victoria Sanz-Moreno, Oscar Maiques, Roberta Ferraldeschi, Simone Jueliger, Shaun Decordova, Ruth Ruddle, Alvaro H. Ingles Garces, Jessica S. Brown, Joaquin Mateo, Dionysis Papadatos-Pastos, Rajiv Kumar, Robert McLeod
Purpose:AT13148 is an oral AGC kinase inhibitor, which potently inhibits ROCK and AKT kinases. In preclinical models, AT13148 has been shown to have antimetastatic and antiproliferative activity.Patients and Methods:The trial followed a rolling six d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a333c1f82c5ff3931176d17bb6ff2c
https://doi.org/10.1158/1078-0432.c.6529065.v1
https://doi.org/10.1158/1078-0432.c.6529065.v1
Autor:
Udai Banerji, Michelle D. Garrett, Florence I. Raynaud, Karen E. Swales, Sarah Mellor, Gavin Halbert, Stephanie Traub, Paul Jones, Victoria Sanz-Moreno, Oscar Maiques, Roberta Ferraldeschi, Simone Jueliger, Shaun Decordova, Ruth Ruddle, Alvaro H. Ingles Garces, Jessica S. Brown, Joaquin Mateo, Dionysis Papadatos-Pastos, Rajiv Kumar, Robert McLeod
Inclusion/Exclusion Criteria and Pharmacokinetic Analytical Method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5127ad704e76e04993609e6ace90960e
https://doi.org/10.1158/1078-0432.22475382
https://doi.org/10.1158/1078-0432.22475382
Autor:
Udai Banerji, Michelle D. Garrett, Florence I. Raynaud, Karen E. Swales, Sarah Mellor, Gavin Halbert, Stephanie Traub, Paul Jones, Victoria Sanz-Moreno, Oscar Maiques, Roberta Ferraldeschi, Simone Jueliger, Shaun Decordova, Ruth Ruddle, Alvaro H. Ingles Garces, Jessica S. Brown, Joaquin Mateo, Dionysis Papadatos-Pastos, Rajiv Kumar, Robert McLeod
Relationship between dose and AUC/Cmax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680ddacf31e0bd6d533d55ce226c23b9
https://doi.org/10.1158/1078-0432.22475379
https://doi.org/10.1158/1078-0432.22475379
Autor:
Udai Banerji, Michelle D. Garrett, Florence I. Raynaud, Karen E. Swales, Sarah Mellor, Gavin Halbert, Stephanie Traub, Paul Jones, Victoria Sanz-Moreno, Oscar Maiques, Roberta Ferraldeschi, Simone Jueliger, Shaun Decordova, Ruth Ruddle, Alvaro H. Ingles Garces, Jessica S. Brown, Joaquin Mateo, Dionysis Papadatos-Pastos, Rajiv Kumar, Robert McLeod
Demographic Profile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5956b87f62609112cab6983b09499bd
https://doi.org/10.1158/1078-0432.22475376.v1
https://doi.org/10.1158/1078-0432.22475376.v1
Autor:
Jonathon Taylor, Robert McLeod, Giorgos Petrou, Christina Hopfe, Anna Mavrogianni, Raúl Castaño-Rosa, Sofie Pelsmakers, Kevin Lomas
Rising global temperatures and more frequent heatwaves due to climate change have led to a growing body of research and increased policy focus on how to protect against the adverse effects of heat. In cold and temperate Europe, dwellings have traditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c6c45c19956f37966cf08b9f7f9922
https://trepo.tuni.fi/handle/10024/146730
https://trepo.tuni.fi/handle/10024/146730
Publikováno v:
The Journal of Laryngology & Otology. 135:1069-1074
ObjectiveGlobally, South Asia has the highest proportion of disabling hearing loss. There is a paucity of data exploring the associated hearing loss and disability caused by chronic middle-ear disease in South Asia in the setting of surgical outreach
TESTING USER PERCEPTI ONS OF RETROFITTED COVID-19 VENTILATION SYSTEMS IN NATURALLY VENTILATED SPACES
Publikováno v:
Proceedings of BauSim 2022: 9th Conference of IBPSA-Germany and Austria.