Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Robert McCuaig"'
1
Akademický článek
Epigenetic programming of T cells impacts immune reconstitution in hematopoietic stem cell transplant recipients
Autor: Kristine Hardy, Corey Smith, Wen Juan Tu, Robert McCuaig, Archana Panikkar, Vijayendra Dasari, Fan Wu, Siok-Keen Tey, Geoffrey R. Hill, Rajiv Khanna, Sudha Rao
Publikováno v: Blood Advances, Vol 2, Iss 6, Pp 656-668 (2018)
Abstract: Immune reconstitution following hematopoietic stem cell transplantation (HSCT) is critical in preventing harmful sequelae in recipients with cytomegalovirus (CMV) infection. To understand the molecular mechanisms underlying immune reconstit
Externí odkaz: https://doaj.org/article/d79e142e77da433a926ab44506f0c2b4
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2
Akademický článek
Lysine-Specific Histone Demethylase 1A Regulates Macrophage Polarization and Checkpoint Molecules in the Tumor Microenvironment of Triple-Negative Breast Cancer
Autor: Abel H. Y. Tan, WenJuan Tu, Robert McCuaig, Kristine Hardy, Thomasina Donovan, Sofiya Tsimbalyuk, Jade K. Forwood, Sudha Rao
Publikováno v: Frontiers in Immunology, Vol 10 (2019)
Macrophages play an important role in regulating the tumor microenvironment (TME). Here we show that classical (M1) macrophage polarization reduced expression of LSD1, nuclear REST corepressor 1 (CoREST), and the zinc finger protein SNAIL. The LSD1 i
Externí odkaz: https://doaj.org/article/fa58d0cc818e45e3b5c4a9a20e3e4310
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3
Akademický článek
Differential Roles for DUSP Family Members in Epithelial-to-Mesenchymal Transition and Cancer Stem Cell Regulation in Breast Cancer.
Autor: Tara Boulding, Fan Wu, Robert McCuaig, Jennifer Dunn, Christopher R Sutton, Kristine Hardy, Wenjuan Tu, Amanda Bullman, Desmond Yip, Jane E Dahlstrom, Sudha Rao
Publikováno v: PLoS ONE, Vol 11, Iss 2, p e0148065 (2016)
Dual-specificity phosphatases (DUSPs) dephosphorylate threonine/serine and tyrosine residues on their substrates. Here we show that DUSP1, DUSP4, and DUSP6 are involved in epithelial-to-mesenchymal transition (EMT) and breast cancer stem cell (CSC) r
Externí odkaz: https://doaj.org/article/6104772fd8cc4575ae4600f1bfcb5010
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4
Akademický článek
Rhinovirus 3C protease facilitates specific nucleoporin cleavage and mislocalisation of nuclear proteins in infected host cells.
Autor: Erin J Walker, Parisa Younessi, Alex J Fulcher, Robert McCuaig, Belinda J Thomas, Philip G Bardin, David A Jans, Reena Ghildyal
Publikováno v: PLoS ONE, Vol 8, Iss 8, p e71316 (2013)
Human Rhinovirus (HRV) infection results in shut down of essential cellular processes, in part through disruption of nucleocytoplasmic transport by cleavage of the nucleoporin proteins (Nups) that make up the host cell nuclear pore. Although the HRV
Externí odkaz: https://doaj.org/article/627b7df5387e406091a20b34869d192e
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8
Abstract CT567: Comprehensive measures of COVID-19 vaccine efficacy in adolescent cancer patients: Results from SerOzNET
Autor: Eva Segelov, Amy Body, Stuart Turville, Corey Smith, Katie Lineburg, Sudha Rao, Robert McCuaig, Stephen Opat, Zin Niang, Luxi Lal, Vi Luong, Hesham Abdulla, Veronica Aedo Lopez, Bhavna Padhye, Noemi Fuentes Bolanos, Antoinette Anazodo, Raina MacIntyre, Peter Downie, Tracey O'Brien, Elizabeth Ahern
Publikováno v: Cancer Research. 82:CT567-CT567
The authors did not submit an updated abstract. The original abstract should be considered final. Citation Format: Eva Segelov, Amy Body, Stuart Turville, Corey Smith, Katie Lineburg, Sudha Rao, Robert McCuaig, Stephen Opat, Zin Niang, Luxi Lal, Vi L
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ba2ef4ec191f02f5d72098ae8a83f9f
https://doi.org/10.1158/1538-7445.am2022-ct567
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10
Nuclear-Biased DUSP6 Expression is Associated with Cancer Spreading Including Brain Metastasis in Triple-Negative Breast Cancer
Autor: Robert McCuaig, Yoshni Jeelall, Laeeq Malik, Jin Dai, Abel Tan, Christopher R Sutton, Desmond Yip, Fan Wu, Jacob Batham, Elaine G. Bean, Jane E. Dahlstrom, Sudha Rao, Thiru Prasanna
Publikováno v: International Journal of Molecular Sciences
Volume 20
Issue 12
International Journal of Molecular Sciences, Vol 20, Iss 12, p 3080 (2019)
DUSP6 is a dual-specificity phosphatase (DUSP) involved in breast cancer progression, recurrence, and metastasis. DUSP6 is predominantly cytoplasmic in HER2+ primary breast cancer cells, but the expression and subcellular localization of DUSPs, espec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcecb62faa49ab4aaf4f178076bbe6f8
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