Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Robert Massé"'
Autor:
Jan Welink, Brian Booth, Eric Woolf, Marc Lefebvre, Natasha Savoie, Chris Beaver, Steve Lowes, Jason Wakelin-Smith, Eric Ormsby, Mario Rocci, Joleen T. White, Peter van Amsterdam, Joseph C Marini, Louise Mawer, Mohammed Jemal, Christopher P. Evans, Robert Massé, Fabio Garofolo, Surendra Bansal, Patrick Bedford, Arthur Leonardo Lopes de Silva, CT Viswanathan
Publikováno v:
Bioanalysis. 2:1945-1960
The 4th Calibration and Validation Group Workshop on Recent Issues in Regulated Bioanalysis, a 2-day full immersion workshop, was organized by the Calibration and Validation Group. Contract research organizations, pharmaceutical companies and regulat
Autor:
Jacques Prévost, Gilles O'Hara, Jacques Turgeon, Robert Massé, Chantale Simard, Rudolf Guilbaud
Publikováno v:
European Journal of Clinical Pharmacology. 57:229-234
Objective: The objective of our study was to evaluate in humans the drug–drug interaction occurring during the concomitant administration of cisapride and simvastatin, two well-known substrates of CYP3A4. Methods: Eleven healthy men aged between 20
Autor:
Leebert A. Wright, Robert Massé
Publikováno v:
Clinical Biochemistry. 29:321-331
Objectives: This report provides the results of the development and evaluation of definitive isotope dilution/mass spectrometry (ID/MS) methods for the determination of testosterone and 17α-hydroxyprogesterone in human plasma at concentrations rangi
Publikováno v:
Steroids. 57:453-459
Two major unconjugated acidic metabolites of oxymetholone (17 beta-hydroxy-2-hydroxymethylene-17 alpha-methyl-5 alpha-androstan-3-one, 1), namely, 17 beta-hydroxy-17 alpha-methyl-2,3-seco-5 alpha-androstane-2,3-dioic acid (2) and 3 alpha,17 beta-dihy
Publikováno v:
Steroids. 57:306-312
A simple and convenient method has been developed to prepare sulfates of anabolic 17 beta-hydroxy-17 alpha-methyl steroids. The sulfates of methandienone, 17 alpha-methyltestosterone, mestanolone, oxandrolone, and stanozolol were prepared. Different
Autor:
Robert Massé, Honggang Bi
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 42:533-546
The epimerization and dehydration reactions of the 17 beta-hydroxy group of anabolic 17 beta-hydroxy-17 alpha-methyl steroids have been investigated using the pyridinium salts of 17 beta-sulfate derivatives of methandienone 1, methyltestosterone 4, o
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 42:229-242
One of the biotransformation routes of oxymetholone (17 beta-hydroxy-2-hydroxymethylene-17 alpha-methyl-5 alpha-androstan-3-one) in man leads to the formation of 17 beta-hydroxy-17 alpha-methyl-5 alpha-androstan-3-one (mestanolone). To demonstrate th
Autor:
Robert, Massé, Bernard F, Gibbs
Publikováno v:
Methods of biochemical analysis. 45
Publikováno v:
Analytica Chimica Acta. 247:211-221
The metabolism of formebolone in man is described. After Sep-Pak C18 extraction, the free, conjugated and acidic steroids were separated. After enzymatic hydrolysis of the conjugates, the neutral steroids were identified by GC—MS. Two metabolites i