Výsledky vyhledávání - "Robert Margolskee"

Akademický článek

Injury-induced pulmonary tuft cells are heterogenous, arise independent of key Type 2 cytokines, and are dispensable for dysplastic repair

Autor: Justinn Barr, Maria Elena Gentile, Sunyoung Lee, Maya E Kotas, Maria Fernanda de Mello Costa, Nicolas P Holcomb, Abigail Jaquish, Gargi Palashikar, Marcella Soewignjo, Margaret McDaniel, Ichiro Matsumoto, Robert Margolskee, Jakob Von Moltke, Noam A Cohen, Xin Sun, Andrew E Vaughan

Publikováno v: eLife, Vol 11 (2022)

While the lung bears significant regenerative capacity, severe viral pneumonia can chronically impair lung function by triggering dysplastic remodeling. The connection between these enduring changes and chronic disease remains poorly understood. We r

Externí odkaz: https://doaj.org/article/08d5c8bc81ec449093dbff776b23790d

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Panning transfected cells for electrophysiological studies

Autor: Robert Margolskee, McHendry-Rinde B, Horn R

Publikováno v: Scopus-Elsevier
Europe PubMed Central

Panning was used to select co-transfected cells expressing plasmid-encoded ion channels. Adherent cells were cotransfected by the CaPO4 method with a plasmid encoding a cell surface marker (CD8) along with another plasmid encoding an ion channel. At

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::92d91266a763672fb1cdd4838e9c7f53
https://pubmed.ncbi.nlm.nih.gov/7505602

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Gustducin and transducin: a tale of two G proteins

Autor: Mclaughlin, S. K., Mckinnon, P. J., Robichon, A., Spickofsky, N., Robert Margolskee

Publikováno v: Europe PubMed Central
Scopus-Elsevier

In the vertebrate taste cell, heterotrimeric guanine nucleotide-binding proteins (G proteins) are involved in the transduction of both bitter and sweet taste stimulants. The bitter compound denatonium raises the intracellular Ca2+ concentration in ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::35ef8809b3bdc89b27b113dd4c9cd6db
https://pubmed.ncbi.nlm.nih.gov/8168377

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Amplified expression of tumor necrosis factor receptor in cells transfected with Epstein-Barr virus shuttle vector cDNA libraries

Autor: Heller, R. A., Song, K., Villaret, D., Robert Margolskee, Dunne, J., Hayakawa, H., Ringold, G. M.

Publikováno v: Europe PubMed Central
Scopus-Elsevier

As an approach to isolate the cell-surface receptor for tumor necrosis factor (TNF), we have developed transfectants of human B-lymphoblastoid cells (UC cells) that overexpress the TNF receptor. These transfectants were isolated from UC cells transfe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::eafbc99417bb06a62354d2d0cbff6cb8
http://europepmc.org/abstract/med/2156825

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