Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Robert Mans"'
Publikováno v:
Biotechnology for Biofuels and Bioproducts, Vol 16, Iss 1, Pp 1-17 (2023)
Abstract Background Anaerobic Saccharomyces cerevisiae cultures require glycerol formation to re-oxidize NADH formed in biosynthetic processes. Introduction of the Calvin-cycle enzymes phosphoribulokinase (PRK) and ribulose-1,5-bisphosphate carboxyla
Externí odkaz:
https://doaj.org/article/d8519f4b93a14b009e7c897246acb691
Publikováno v:
Biotechnology for Biofuels and Bioproducts, Vol 15, Iss 1, Pp 1-15 (2022)
Abstract Background Saccharomyces cerevisiae is intensively used for industrial ethanol production. Its native fermentation pathway enables a maximum product yield of 2 mol of ethanol per mole of glucose. Based on conservation laws, supply of additio
Externí odkaz:
https://doaj.org/article/88f2635006e6476cb4738c4273198c71
Autor:
Zahabiya Malubhoy, Frederico Mendonça Bahia, Sophie Claire de Valk, Erik de Hulster, Toni Rendulić, Juan Paulo Ragas Ortiz, Joeline Xiberras, Mathias Klein, Robert Mans, Elke Nevoigt
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-15 (2022)
Abstract Background The microbial production of succinic acid (SA) from renewable carbon sources via the reverse TCA (rTCA) pathway is a process potentially accompanied by net-fixation of carbon dioxide (CO2). Among reduced carbon sources, glycerol i
Externí odkaz:
https://doaj.org/article/ef8bb4c8c8a548dea7c793046cedeb49
Autor:
Aafke C.A. van Aalst, Sophie C. de Valk, Walter M. van Gulik, Mickel L.A. Jansen, Jack T. Pronk, Robert Mans
Publikováno v:
Synthetic and Systems Biotechnology, Vol 7, Iss 1, Pp 554-566 (2022)
Product yield on carbohydrate feedstocks is a key performance indicator for industrial ethanol production with the yeast Saccharomyces cerevisiae. This paper reviews pathway engineering strategies for improving ethanol yield on glucose and/or sucrose
Externí odkaz:
https://doaj.org/article/4028fff629bf44c2b97cdda63b541213
Autor:
Cláudia Barata-Antunes, Rosana Alves, Gabriel Talaia, Margarida Casal, Hernâni Gerós, Robert Mans, Sandra Paiva
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 1713-1737 (2021)
Plasma membrane transporters play pivotal roles in the import of nutrients, including sugars, amino acids, nucleobases, carboxylic acids, and metal ions, that surround fungal cells. The selective removal of these transporters by endocytosis is one of
Externí odkaz:
https://doaj.org/article/1e68f8d1252b4574905da416905df48e
Autor:
Sophie Claire de Valk, Robert Mans
Publikováno v:
Journal of Fungi, Vol 8, Iss 4, p 358 (2022)
A major challenge in the research of transport proteins is to understand how single amino acid residues contribute to their structure and biological function. Amino acid substitutions that result in a selective advantage in adaptive laboratory evolut
Externí odkaz:
https://doaj.org/article/df660acf1ce04c33be367fb830113be2
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Previously, our lab replaced the endogenous FAD-dependent pathway for glycerol catabolism in S. cerevisiae by the synthetic NAD-dependent dihydroxyacetone (DHA) pathway. The respective modifications allow the full exploitation of glycerol’s higher
Externí odkaz:
https://doaj.org/article/3962a4a6f1e247c48f9cbc8d0cc7decd
In anaerobicSaccharomyces cerevisiaecultures, NADH-cofactor balancing by glycerol formation constrains ethanol yields. Introduction of an acetate-to-ethanol reduction pathway based on heterologous acetylating acetaldehyde dehydrogenase (A-ALD) can re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c69e7193987d2a8347ffa9047a7e8d58
https://doi.org/10.1101/2023.05.21.541164
https://doi.org/10.1101/2023.05.21.541164
Autor:
Harshil Dharamdasani Detaram, MBBS, MPhil, Phuong H.D. Nguyen, MBBS, Veronica C. Wong, MBBS, FRACP, FAANMS, Han Loh, MBBS, FRANZCR, FAANMS, Robert Mansberg, MBBS, FRACP, FAANMS
Publikováno v:
Radiology Case Reports, Vol 19, Iss 10, Pp 4517-4521 (2024)
A 77-year-old man with a history of left nephrectomy for renal cell carcinoma and partial hepatectomy for cholangiocarcinoma underwent 18F-FDG PET/CT for assessment of an irregular lung lesion. FDG-PET demonstrated development of an intensely avid sp
Externí odkaz:
https://doaj.org/article/f3d2a3cf55a542c3a249a79538f29086
Autor:
Tsu-Yi Su, Julia Hauenstein, Ece Somuncular, Özge Dumral, Elory Leonard, Charlotte Gustafsson, Efthymios Tzortzis, Aurora Forlani, Anne-Sofie Johansson, Hong Qian, Robert Månsson, Sidinh Luc
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Age is a risk factor for hematologic malignancies. Attributes of the aging hematopoietic system include increased myelopoiesis, impaired adaptive immunity, and a functional decline of the hematopoietic stem cells (HSCs) that maintain hematop
Externí odkaz:
https://doaj.org/article/ce8fe9bb60494b84ad3652fa933d6098