Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Robert Mack Riggs"'
Autor:
Peter A. Crooks, Robert Mack Riggs, K. M. Chang, J. M. Greene, J. D. Debethizy, William S. Caldwell, Bhatti Balwinder Singh, M. S. Uhrig, Gary D. Byrd
Publikováno v:
Chemical Research in Toxicology. 5:280-285
Recent studies in our laboratories have confirmed that a major unidentified metabolite of nicotine in smokers' urine was susceptible to enzymatic degradation by beta-glucuronidase to afford (S)-(-)-cotinine. In order to establish the identity of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aea6013f56cfa4d07fe3160fca5444e
https://doi.org/10.1021/tx00026a021
https://doi.org/10.1021/tx00026a021
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(7)
The purpose of this study was to synthesize and study the in vitro enzymatic and non-enzymatic hydrolysis of indomethacin–TEG ester and amide prodrugs. It was found that the ester conjugate 10 was comparatively stable between pH 3 and 6 (half-life
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1babe9123f8ce404cbd5a36eb6313c22
https://pubmed.ncbi.nlm.nih.gov/16439128
https://pubmed.ncbi.nlm.nih.gov/16439128
Autor:
Robert Mack Riggs, William S. Caldwell, Peter A. Crooks, M. S. Uhrig, Gary D. Byrd, J. D. Debethizy, Alain Ravard
Publikováno v:
Biological mass spectrometry. 23(2)
A thermospray liquid chromatographic/mass spectrometric method has been developed for direct determination of cotinine-N-glucuronide in the urine of smokers. Quantification was performed using methyl-d3-cotinine-N-glucuronide as internal standard and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82df61cd640b13d7a841e9a27104f9ed
https://pubmed.ncbi.nlm.nih.gov/8123688
https://pubmed.ncbi.nlm.nih.gov/8123688
Publikováno v:
The Journal of Organic Chemistry. 44:1746-1747
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fe7fe0120be0f36922f3fcee2d0820e
https://doi.org/10.1021/jo01324a048
https://doi.org/10.1021/jo01324a048