Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Robert M. Verdijk"'
Autor:
Josephine Q.N. Nguyen, MD, Wojtek Drabarek, MD, PhD, Jolanda Vaarwater, BS, Serdar Yavuzyigitoglu, MD, PhD, Robert M. Verdijk, MD, PhD, Dion Paridaens, MD, PhD, Nicole C. Naus, MD, PhD, Annelies de Klein, PhD, Erwin Brosens, PhD, Emine Kiliç, MD, PhD, Emine Kilic, Annelies de Klein, Erwin Brosens, Nicole C. Naus, Dion Paridaens, Serdar Yavuzyigitoglu, Wojtek Drabarek, Josephine Q.N. Nguyen, Jolanda Vaarwater, Robert M. Verdijk
Publikováno v:
Ophthalmology Science, Vol 4, Iss 2, Pp 100413- (2024)
Purpose: Gain of chromosome 8q has been associated with poor prognosis in uveal melanoma (UM), and an increase in the absolute number of 8q-copies correlated with an even shorter survival. Splicing factor 3b subunit 1 (SF3B1)-mutated (SF3B1MUT) tumor
Externí odkaz:
https://doaj.org/article/934cfbc783cf4851b533eb756d1dfc3c
Autor:
Robert M. Verdijk
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 6896 (2024)
The goal of this Special Issue is to provide comprehensive molecular biological data that aims to elucidate the molecular and epigenetic mechanisms operable in diseases of the ocular adnexa [...]
Externí odkaz:
https://doaj.org/article/00bfcf5a54b340a08fffe289bf9ba78c
Autor:
Maria Chiara Gelmi, MD, Annemijn P.A. Wierenga, MD, Wilma G.M. Kroes, MSc, Sjoerd G. van Duinen, MD, PhD, Jessica S. Karuntu, MD, Marina Marinkovic, MD, Jaco C. Bleeker, MD, Gregorius P.M. Luyten, MD, PhD, T.H. Khanh Vu, MD, PhD, Robert M. Verdijk, MD, PhD, Martine J. Jager, MD, PhD
Publikováno v:
Ophthalmology Science, Vol 3, Iss 3, Pp 100297- (2023)
Purpose: Heavy pigmentation is known to be a prognostic risk factor in uveal melanoma (UM). We analyzed whether genetic tumor parameters were associated with tumor pigmentation and whether pigmentation should be included in prognostic tests. Design:
Externí odkaz:
https://doaj.org/article/07475fd972c34e2ca066b7680ff4d681
Autor:
Wilmar Ghuijs, Paul G. Kemps, Marta E. Capala, Robert M. Verdijk, Astrid G. S. van Halteren, Robert J. P. van der Wal, Jan A. M. van Laar
Publikováno v:
Radiation Oncology, Vol 17, Iss 1, Pp 1-6 (2022)
Abstract Background Langerhans cell histiocytosis (LCH) is a rare haematological neoplasm characterized by the accumulation of CD1a+, CD207/Langerin+ histiocytes within inflammatory lesions. LCH can involve any organ, but osteolytic bone lesions are
Externí odkaz:
https://doaj.org/article/2a1e48c1278d484c9f48c5c4430ffc82
Autor:
Saskia H. M. van Romunde, Daphne P. C. Vergouwen, Daniela Iacovello, Dave L. Roelen, Robert M. Verdijk, Josianne C. E. M. ten Berge, Grazia Pertile, Marco W. J. Schreurs, Jan C. van Meurs
Publikováno v:
Journal of Ophthalmic Inflammation and Infection, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Purpose Five patients who underwent uncomplicated retinal pigment epithelium (RPE)-choroid transplantation for neovascular age-related macular degeneration developed a destructive inflammatory reaction causing subretinal fluid accumulation a
Externí odkaz:
https://doaj.org/article/c0f2e10b1c0a4c55b8aac00827160632
Autor:
Floris V.W.J. van Zijl, MD, Peter C.J. de Laat, MD, PhD, Robert M. Verdijk, MD, PhD, Andries P. Nagtegaal, MD, PhD, Frank R. Datema, MD, PhD
Publikováno v:
JAAD Case Reports, Vol 26, Iss , Pp 45-48 (2022)
Externí odkaz:
https://doaj.org/article/91115865d6a543ed97c344df4dfd2738
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 29, Iss , Pp 101730- (2023)
A 66-year-old woman presented to a tertiary referral centre with a diagnosis of limbal stem cell deficiency secondary to multiple treatments for primary acquired melanosis (PAM) by her referring ophthalmologists. She was known with primary acquired m
Externí odkaz:
https://doaj.org/article/1425725de43b41ac93afd9b4a365107f
Autor:
Kyra N. Smit, Ruben Boers, Jolanda Vaarwater, Joachim Boers, Tom Brands, Hanneke Mensink, Robert M. Verdijk, Wilfred F. J. van IJcken, Joost Gribnau, Annelies de Klein, Emine Kilic
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Uveal melanoma (UM) is an aggressive intra-ocular cancer with a strong tendency to metastasize. Metastatic UM is associated with mutations in BAP1 and SF3B1, however only little is known about the epigenetic modifications that arise in metas
Externí odkaz:
https://doaj.org/article/917f2aa09fc549bf8c581c8646258bb0
Autor:
Suzanna L. Roohé, Ivan M. Gan, Kim van der Weerd, Boaz Lopuhaä, Robert M. Verdijk, Dion Paridaens
Publikováno v:
Case Reports in Ophthalmology, Vol 12, Iss 3, Pp 870-874 (2021)
Orbital metastasis may be the initial manifestation of a malignancy of unknown origin. The primary locations of orbital metastasis are usually the lung, prostate, gastrointestinal tract, skin, kidney, eye, or thyroid gland. Metastasis of gastric carc
Externí odkaz:
https://doaj.org/article/c147a58266f34ff3abc99bda74ecfd09
Autor:
Jolique A. van Ipenburg, Quincy C. C. van den Bosch, Dion Paridaens, Hendrikus J. Dubbink, Emine Kiliç, Nicole Naus, Robert M. Verdijk
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12988 (2023)
Metastatic disease is linked to TERT promoter mutations in conjunctival melanomas (CM). Both TERT promoter and ATRX mutations are associated with faulty telomere maintenance. This study aimed to determine the prognostic value of ATRX loss in conjunct
Externí odkaz:
https://doaj.org/article/895e9835444b4bb29ca29a4d6add6c6a