Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Robert M. Petitt"'
Publikováno v:
Leukemia Research. 29:481-491
Appropriate treatment for nonreactive thrombocytosis resulting from a myeloproliferative disorder (MPD) is surrounded by controversy. Although few doubt the association of thrombocytosis with increased risk for life-threatening events such as thrombo
Publikováno v:
Seminars in Thrombosis and Hemostasis. 23:379-383
Anagrelide is an oral imidazoquinazoline agent with an anti-cyclic AMP phosphodiesterase activity and inhibits platelet aggregation in both humans and animals. In addition, it has in humans a species-specific platelet-lowering activity observed at do
Publikováno v:
Mayo Clinic Proceedings. 66:602-607
We studied the prognostic value of computed tomography (CT) of the brain for neurologic morbidity in patients with thrombotic thrombocytopenic purpura. On review of Mayo Clinic records for 1975 through 1985, we found 32 patients with thrombotic throm
Publikováno v:
Mayo Clinic Proceedings. 66:287-299
Chromosome studies were done in 104 patients with various stages of polycythemia vera (PV): 10 had leukemia-myelodysplastic syndrome, 28 had post-PV with myeloid metaplasia (PPVMM), 12 had PV with myelofibrosis, and 54 had PV. Chromosome studies were
Autor:
Patricia J.M. Best, Robert M. Petitt
Publikováno v:
Mayo Clinic proceedings. 73(10)
The association of multiple cutaneous cancers and long-term use of hydroxyurea is now being recognized. In this article, we describe the development of multiple skin tumors in two patients who were receiving hydroxyurea therapy. These cases illustrat
Autor:
Robert M. Petitt, Lee A. Forstrom, Murray N. Silverstein, Jerzy S. Tarach, Lawrence A. Solberg, Ayalew Tefferi, Karl J. Oles
Publikováno v:
British journal of haematology. 99(1)
Anagrelide, an inhibitor of platelet aggregation, decreases the number of platelets in normal subjects and in patients with myeloproliferative disorders. We describe studies aimed at discovering the general mechanism(s) by which anagrelide acts. We e
Autor:
Ayalew Tefferi, James D. Hoyer, Robert M. Petitt, Virgil F. Fairbanks, Murray N. Silverstein, George G. Klee, Gregory A. Wiseman
Publikováno v:
Blood cells, moleculesdiseases. 22(2)
Comparison of results of red cell mass (RCM) measurement by 51Cr and 125I methods in 119 patients showed virtual equivalence. Both methods have an acceptable coefficient of variation (CV) that is < 5%. The 125I method is simpler and much less expensi
Publikováno v:
Mayo Clinic proceedings. 66(2)
Essential thrombocythemia is typically a disorder of adults in the sixth or seventh decade of life and is characterized by frequent thrombohemorrhagic complications. In young patients, the optimal management of complications is controversial. We stud
Autor:
Robert M. Petitt
Publikováno v:
Blood. 106:4957-4957
Essential thrombocythemia (ET) is a myeloproliferative disorder (MPD) associated with thrombohemorrhagic complications. The disease uncommonly progresses to myelofibrosis or acute leukemia; the risk of transformation may be increased by cytoreductive
Publikováno v:
Annals of Internal Medicine. 129:252