Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Robert M. Moore"'
Publikováno v:
Case Reports in Nephrology, Vol 2015 (2015)
Forniceal rupture is a rare event in pregnancy. We report a case of a 26-year-old primigravid woman who experienced a forniceal rupture at 23 weeks of gestation with no inciting cause except for pregnancy. Pregnancy is associated with ureteral compre
Externí odkaz:
https://doaj.org/article/c21e7bfe53aa4baa8bc5937f7b49cca0
Autor:
Robert M. Moore, Yogangi Malhotra, Daniel M. Lasser, Tianying Li, Clementine Knight, Judith Chervenak, Hugo O. Teo
Publikováno v:
American Journal of Perinatology. 38:1236-1243
Objective This study aimed to determine if laboratory inflammatory markers can predict critical disease in symptomatic COVID-19 pregnant women. Study Design Multicenter, retrospective cohort study of all pregnant women presenting to New York City Hea
Publikováno v:
Obstetrics and Gynecology Clinics of North America. 47:523-544
Using a novel in vitro model system combining biochemical/histologic with bioengineering approaches has provided significant insights into the physiology of fetal membrane weakening and rupture along with potential mechanistic reasons for lack of eff
Publikováno v:
Placenta. 97:79-88
Introduction We use an in-vitro human fetal membrane (FM) explant-based model to study inflammation-induced FM weakening, a prerequisite for PPROM. In this system, GMCSF is a critical intermediate, both necessary and sufficient for TNFα and thrombin
Autor:
Frederick Schatz, Kellie Larsen, Robert M. Moore, Rachel G. Sinkey, Deepak Kumar, Charles J. Lockwood, Sefa Arlier, Asli Ozmen, Nihan Semerci, Xiaofang Guo, Ozlem Guzeloglu-Kayisli, John J. Moore, Chinedu Nwabuobi, Umit A. Kayisli, Lynn F. Buckwalder
Publikováno v:
The American Journal of Pathology. 190:388-399
Preterm premature rupture of membranes (PPROM) and thrombin generation by decidual cell–expressed tissue factor often accompany abruptions. Underlying mechanisms remain unclear. We hypothesized that thrombin-induced colony-stimulating factor-2 (CSF
Autor:
Brian M. Mercer, Robert M. Moore, Joseph M. Mansour, Anudeepa Sharma, Deepak Kumar, Aditi Deshmukh, John J. Moore
Publikováno v:
Placenta. 89
Introduction We have previously demonstrated two associations of PPROM, (1) inflammation/infection (modeled by tumor necrosis factor (TNF)) and (2) decidual bleeding (modeled by thrombin), both decrease fetal membrane (FM) rupture strength in-vitro.
Autor:
Vladimir Bokun, Carrie C. Smallcombe, Frank Esper, Terri J. Harford, Robert M. Moore, John J. Moore, Fariba Rezaee, G. Piedimonte
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0225767 (2019)
PLoS ONE
PLoS ONE
BackgroundRespiratory syncytial virus (RSV) is capable of transient viremia and extrapulmonary dissemination. Recently, this virus has been identified in fetal cord blood, suggesting the possibility of in utero acquisition in humans. Here, we assess
Autor:
Joseph M. Mansour, Brian M. Mercer, Deepak Kumar, Raymond W. Redline, John J. Moore, Robert M. Moore
Publikováno v:
Placenta. 42:59-73
Rupture of the fetal membranes (FM) is precipitated by stretch forces acting upon biochemically mediated, pre-weakened tissue. Term FM develop a para-cervical weak zone, characterized by collagen remodeling and apoptosis, within which FM rupture is t
Autor:
Bradley Stetzer, Robert M. Moore, John J. Moore, A. Strohl, S. Tamarkin, Deepak Kumar, Erinn M. Joyce, P. Diaz, Michael S. Sacks
Publikováno v:
Placenta. 38:57-66
Introduction Fetal membranes (FM) usually fail prior to delivery during term labor, but occasionally fail at preterm gestation, precipitating preterm birth. To understand the FM biomechanical properties underlying these events, study of the baseline