Zobrazeno 1 - 10
of 1 572
pro vyhledávání: '"Robert M. Hoffman"'
Autor:
Chunlin Lin, Penghang Lin, Huayan Lin, Hengxin Yao, Songyi Liu, Ruofan He, Hui Chen, Zuhong Teng, Robert M. Hoffman, Jianxin Ye, Guangwei Zhu
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-16 (2023)
Abstract Colorectal cancer (CRC) is a formidable disease due to the intricate mechanisms that drive its proliferation and metastasis. Despite significant progress in cancer research, the integration of these mechanisms that influence cancer cell beha
Externí odkaz:
https://doaj.org/article/60672eb4ed3f487e8c81589a0ef27c76
Autor:
Nanako Takaoka, Michiko Yamane, Ayami Hasegawa, Koya Obara, Kyoumi Shirai, Ryoichi Aki, Hiroyasu Hatakeyama, Yuko Hamada, Nobuko Arakawa, Manabu Tanaka, Robert M. Hoffman, Yasuyuki Amoh
Publikováno v:
PLoS ONE, Vol 19, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/11c57011c8714e53a7156e8220d43520
Autor:
Yanyu Jiang, Zhimei Tang, Xiaogang Zhu, Biying Xiao, Hechuan Tian, Xingxing Lei, Huan Peng, Jun Qin, Yanmei Zhang, Robert M. Hoffman, Xiaorong Hu, Qiu Chen, Guang Ji, Lijun Jia
Publikováno v:
MedComm, Vol 4, Iss 6, Pp n/a-n/a (2023)
Abstract Fasting has been grown in popularity with multiple potential benefits. However, very few studies dynamically monitor physiological and pathological changes during long‐term fasting using noninvasive methods. In the present study, we recrui
Externí odkaz:
https://doaj.org/article/cebe02e949d24cd8a1ee34245b4c5cca
Autor:
Michael A. Turner, Kristin E. Cox, Shanglei Liu, Nicholas Neel, Siamak Amirfakhri, Hiroto Nishino, Mojgan Hosseini, Joshua A. Alcantara, Amer Ali Abd El-Hafeez, Thinzar M. Lwin, Kavita Mallya, Joseph R. Pisegna, Satish K. Singh, Pradipta Ghosh, Robert M. Hoffman, Surinder K. Batra, Michael Bouvet
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 4, Pp 3347-3358 (2023)
Poor visualization of polyps can limit colorectal cancer screening. Fluorescent antibodies to mucin5AC (MUC5AC), a glycoprotein upregulated in adenomas and colorectal cancer, could improve screening colonoscopy polyp detection rate. Adenomatous polyp
Externí odkaz:
https://doaj.org/article/0a7999883a40427280a4ee5a75ae457b
Autor:
Penghang Lin, Chunlin Lin, Ruofan He, Hui Chen, Zuhong Teng, Hengxin Yao, Songyi Liu, Robert M. Hoffman, Jianxin Ye, Guangwei Zhu
Publikováno v:
Cell Death and Disease, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Colorectal cancer cannot be completely cured at present, and it is still an important clinical medical problem. TRAF6 is highly expressed in many malignant tumors. However, the role of TRAF6 in colorectal cancer is still controversial, mainl
Externí odkaz:
https://doaj.org/article/25234541ad1c49eebfe133f7b33b12e3
Autor:
Koya Obara, Jose Reynoso, Yuko Hamada, Yusuke Aoki, Yutaro Kubota, Noriyuki Masaki, Yasuyuki Amoh, Robert M. Hoffman
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Stimulation of hair growth in hair loss has been a difficult goal to achieve. Hair follicle-associated pluripotent (HAP) stem cells express nestin and have been shown to differentiate to multiple cell types including keratinocytes, neurons,
Externí odkaz:
https://doaj.org/article/99609dc74f7f42f284f939019321b60a
Autor:
Paulina Marona, Judyta Górka, Oliwia Kwapisz, Jolanta Jura, Janusz Rys, Robert M. Hoffman, Katarzyna Miekus
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-17 (2022)
Abstract Tyrosine kinase inhibitors (TKIs) are the most commonly used targeted therapeutics in clear-cell renal cell carcinoma (ccRCC); however, drug resistance limits their utility and can lead to tumor “flare-up” and progression. In this study,
Externí odkaz:
https://doaj.org/article/b9b7dba8693f4e029e928c26b9639543
Autor:
Shuaishuai Ni, Qian Liu, Xin Chen, Lele Ding, Lili Cai, Fei Mao, Donglei Shi, Robert M. Hoffman, Jian Li, Lijun Jia
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/53198fa59feb42b3a13be40d57100d84
Autor:
Kristin E. Cox, Shanglei Liu, Robert M. Hoffman, Surinder K. Batra, Punita Dhawan, Michael Bouvet
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 272 (2024)
Claudins (CLDN1–CLDN24) are a family of tight junction proteins whose dysregulation has been implicated in tumorigeneses of many cancer types. In colorectal cancer (CRC), CLDN1, CLDN2, CLDN4, and CLDN18 have been shown to either be upregulated or a
Externí odkaz:
https://doaj.org/article/8514284706d44dee8d5093f86f953c83
Autor:
Jingrong Xian, Shiwen Wang, Yanyu Jiang, Lihui Li, Lili Cai, Ping Chen, Yue Liu, Xiaofei Zeng, Guoan Chen, Chen Ding, Robert M. Hoffman, Lijun Jia, Hu Zhao, Yanmei Zhang
Publikováno v:
Cancer Biology & Medicine, Vol 19, Iss 4, Pp 504-517 (2022)
Objective: The hyperactivated neddylation pathway plays an important role in tumorigenesis and is emerging as a promising anticancer target. We aimed to study whether NEDD8 (neural precursor cell expressed, developmentally down-regulated 8) might ser
Externí odkaz:
https://doaj.org/article/2e86f6805a4d485ea2910e9d04d34ec4