Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Robert M. Gemmill"'
Autor:
Rajeev Dhupar, Amy A. Powers, Seth H. Eisenberg, Robert M. Gemmill, Charles E. Bardawil, Hannah M. Udoh, Andrea Cubitt, Leslie A. Nangle, Adam C. Soloff
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 5, p 1446 (2024)
Immunity has evolved to balance the destructive nature of inflammation with wound healing to overcome trauma, infection, environmental insults, and rogue malignant cells. The inflammatory response is marked by overlapping phases of initiation, resolu
Externí odkaz:
https://doaj.org/article/f21b7f0599ea4845814d8e2fdd524a4d
Autor:
Rajeev Dhupar, Katherine E. Jones, Amy A. Powers, Seth H. Eisenberg, Kai Ding, Fangyuan Chen, Cecile Nasarre, Zhanpeng Cen, Yi-Nan Gong, Amanda C. LaRue, Elizabeth S. Yeh, James D. Luketich, Adrian V. Lee, Steffi Oesterreich, Michael T. Lotze, Robert M. Gemmill, Adam C. Soloff
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tumor-associated macrophages (TAMs) exert profound influence over breast cancer progression, promoting immunosuppression, angiogenesis, and metastasis. Neuropilin-2 (NRP2), consisting of the NRP2a and NRP2b isoforms, is a co-receptor for heparin-bind
Externí odkaz:
https://doaj.org/article/827b40d579f747be836c2d0874271b4e
Autor:
Muhammad Zaeem Noman, Kris Van Moer, Vanessa Marani, Robert M. Gemmill, Léon-Charles Tranchevent, Francisco Azuaje, Arnaud Muller, Salem Chouaib, Jean Paul Thiery, Guy Berchem, Bassam Janji
Publikováno v:
OncoImmunology, Vol 7, Iss 4 (2018)
We report that CD47 was upregulated in different EMT-activated human breast cancer cells versus epithelial MCF7 cells. Overexpression of SNAI1 or ZEB1 in epithelial MCF7 cells activated EMT and upregulated CD47 while siRNA-mediated targeting of SNAI1
Externí odkaz:
https://doaj.org/article/34235163a76541859218b72351edc35f
Autor:
Jonathan Clarhaut, Robert M. Gemmill, Vincent A. Potiron, Slimane Ait-Si-Ali, Jean Imbert, Harry A. Drabkin, Joëlle Roche
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 2, Pp 157-166 (2009)
SEMA3F is a secreted semaphorin with potent antitumor activity, which is frequently downregulated in lung cancer. In cancer cell lines, SEMA3F overexpression decreases hypoxia-induced factor 1α protein and vascular endothelial growth factor mRNA, an
Externí odkaz:
https://doaj.org/article/594d5153996440ceb867f9f8340dd8c8
Autor:
Sophie Kusy, Patrick Nasarre, Daniel Chan, Vincent Potiron, David Meyronet, Robert M. Gemmill, Bruno Constantin, Harry A. Drabkin, Joëlle Roche
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 5, Pp 457-465 (2005)
Loss of the 3p21.3-encoded semaphorins, SEMA3B and SEMA3F is implicated in lung cancer development. Although both antagonize VEGF binding/response to neuropilin (NRP) receptors, in lung cancer lines,SEMA3F is predominantly expressed and preferentiall
Externí odkaz:
https://doaj.org/article/f2df5a74439e46a79d33cca7710ade01
Publikováno v:
Cancers, Vol 9, Iss 7, p 72 (2017)
Lung cancer is the leading cause of cancer deaths worldwide. It is an aggressive and devastating cancer because of metastasis triggered by enhanced migration and invasion, and resistance to cytotoxic chemotherapy. The epithelial to mesenchymal transi
Externí odkaz:
https://doaj.org/article/a5515e20d2694ff586a7186f1c7534f2
Autor:
Robert M. Gemmill, Harry A. Drabkin, Joan E. Hooper, Michael Rudolph, Anne Brauweiler, Jason P. Lee
Supplementary Data from The TRC8 Ubiquitin Ligase Is Sterol Regulated and Interacts with Lipid and Protein Biosynthetic Pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3aa0dce9b46c2158429f7ca204c0d8
https://doi.org/10.1158/1541-7786.22519312.v1
https://doi.org/10.1158/1541-7786.22519312.v1
Autor:
Harry A. Drabkin, Joëlle Roche, Robert M. Gemmill, Hellmut G. Augustin, Jonathan A. Clarhaut, Patrick Nasarre, Girish Sharma, Vincent A. Potiron
Loss of SEMA3F occurs frequently in lung cancer and correlates with advanced stage of disease. We previously reported that SEMA3F blocked tumor formation by H157 lung cancer cells in a rat orthotopic model. This was associated with loss of activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baf750543b7e966eba2df6c595219940
https://doi.org/10.1158/0008-5472.c.6496748
https://doi.org/10.1158/0008-5472.c.6496748
Autor:
Harry A. Drabkin, Philip H. Howe, Alessandro Lagana, Elizabeth Garrett-Mayer, Christopher Korch, Anna E. Barón, Xian Lu, Joëlle Roche, Vincent A. Potiron, Robert M. Gemmill, Patrick Nasarre
PDF file - 97K, shRNA target sequences (S1); Primers used for quantitative RT-PCR (S2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b796a908396b778be9807651414138a
https://doi.org/10.1158/0008-5472.22396707.v1
https://doi.org/10.1158/0008-5472.22396707.v1
Autor:
Harry A. Drabkin, Philip H. Howe, Alessandro Lagana, Elizabeth Garrett-Mayer, Christopher Korch, Anna E. Barón, Xian Lu, Joëlle Roche, Vincent A. Potiron, Robert M. Gemmill, Patrick Nasarre
PDF file - 70K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33add2cdbbb699a778ef87a4d61a8079
https://doi.org/10.1158/0008-5472.22396710
https://doi.org/10.1158/0008-5472.22396710